Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Bradley J. Merrill"'
Autor:
Boksik Cha, Xin Geng, Md. Riaj Mahamud, Jenny Y. Zhang, Lijuan Chen, Wantae Kim, Eek-hoon Jho, Yeunhee Kim, Dongwon Choi, J. Brandon Dixon, Hong Chen, Young-Kwon Hong, Lorin Olson, Tae Hoon Kim, Bradley J. Merrill, Michael J. Davis, R. Sathish Srinivasan
Publikováno v:
Cell Reports, Vol 25, Iss 3, Pp 571-584.e5 (2018)
Summary: Wnt/β-catenin signaling is necessary for lymphatic vascular development. Oscillatory shear stress (OSS) enhances Wnt/β-catenin signaling in cultured lymphatic endothelial cells (LECs) to induce expression of the lymphedema-associated trans
Externí odkaz:
https://doaj.org/article/673fed9597e44ed68a6c8a45caf4c9d9
Autor:
Brian R. Shy, Chun-I. Wu, Galina F. Khramtsova, Jenny Y. Zhang, Olufunmilayo I. Olopade, Kathleen H. Goss, Bradley J. Merrill
Publikováno v:
Cell Reports, Vol 4, Iss 1, Pp 1-9 (2013)
Wnt/β-catenin signal transduction requires direct binding of β-catenin to Tcf/Lef proteins, an event that is classically associated with stimulating transcription by recruiting coactivators. This molecular cascade plays critical roles throughout em
Externí odkaz:
https://doaj.org/article/b5db10c59d86481b8ddf08ecb102f81a
Publikováno v:
Cell Reports, Vol 3, Iss 6, Pp 2113-2126 (2013)
Wnt signaling is intrinsic to mouse embryonic stem cell self-renewal. Therefore, it is surprising that reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) is not strongly enhanced by Wnt signaling. Here, we demonstrate that activ
Externí odkaz:
https://doaj.org/article/3b09acecabd7405e8969e6a4921fd5f3
Autor:
Dragana Kopanja, Vaibhav Chand, Eilidh O'Brien, Nishit K. Mukhopadhyay, Maria P. Zappia, Abul B.M.M.K. Islam, Maxim V. Frolov, Bradley J. Merrill, Pradip Raychaudhuri
Publikováno v:
Cancer Res
The transcription factor Forkhead box M1 (FoxM1) is overexpressed in breast cancers and correlates with poor prognosis. Mechanistically, FoxM1 associates with CBP to activate transcription and with Rb to repress transcription. Although the activating
Autor:
Pradip Raychaudhuri, Bradley J. Merrill, Maxim V. Frolov, Abul B.M.M.K. Islam, Maria P. Zappia, Nishit K. Mukhopadhyay, Eilidh O'Brien, Vaibhav Chand, Dragana Kopanja
Supplementary Data from Transcriptional Repression by FoxM1 Suppresses Tumor Differentiation and Promotes Metastasis of Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70e1208e3f55b2637eb1da0bcadf5af8
https://doi.org/10.1158/0008-5472.22431851
https://doi.org/10.1158/0008-5472.22431851
Autor:
Pradip Raychaudhuri, Grace Guzman, Srilata Bagchi, Bradley J. Merrill, Damiano Fantini, Shuo Huang
Deregulation of the Wnt/β-catenin signaling pathway drives the development of colorectal cancer, but understanding of this pathway remains incomplete. Here, we report that the damage-specific DNA-binding protein DDB2 is critical for β-catenin–med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::659f19aa2f75bef3486c98fc4bcfeb18
https://doi.org/10.1158/0008-5472.c.6509541.v1
https://doi.org/10.1158/0008-5472.c.6509541.v1
Autor:
Pradip Raychaudhuri, Grace Guzman, Srilata Bagchi, Bradley J. Merrill, Damiano Fantini, Shuo Huang
Table S1: Sequences of DsiRNA; Table S2: Primers for ChIP assays; Table S3: Primers for gene expression assays; Table S4: Correlation analysis of DDB2 and RNF43 expression in patient colonic samples; Table S5:Primers and probes for 3C assay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::584954599e9a68b723181726003da1f7
https://doi.org/10.1158/0008-5472.22416387.v1
https://doi.org/10.1158/0008-5472.22416387.v1
Autor:
Pradip Raychaudhuri, Grace Guzman, Srilata Bagchi, Bradley J. Merrill, Damiano Fantini, Shuo Huang
Figure S6: Association of DDB2, TCF4 and β-catenin on Rnf43 upstream region and intron regions.Figure S7: EZH2 and PAF are required for Rnf43 expression.Figure S8: DDB2 is required for the RNF43-mediated sequestration of TCF4 to the nuclear membrane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e328dbb2a393aea803daf1735ab8668e
https://doi.org/10.1158/0008-5472.22416393.v1
https://doi.org/10.1158/0008-5472.22416393.v1
Autor:
Pradip Raychaudhuri, Grace Guzman, Srilata Bagchi, Bradley J. Merrill, Damiano Fantini, Shuo Huang
Supplementary methods of Protein Extraction, Immunoblotting and Co-immunoprecipitations, Chromatin Conformation Capture Assay, Immunofluorescent Staining and Whole Exome Sequencing (WES)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27acd9e25fd65c244bd3981d45932a06
https://doi.org/10.1158/0008-5472.22416390.v1
https://doi.org/10.1158/0008-5472.22416390.v1
Autor:
Pradip Raychaudhuri, Bradley J. Merrill, Maxim V. Frolov, Abul B.M.M.K. Islam, Maria P. Zappia, Nishit K. Mukhopadhyay, Eilidh O'Brien, Vaibhav Chand, Dragana Kopanja
The transcription factor Forkhead box M1 (FoxM1) is overexpressed in breast cancers and correlates with poor prognosis. Mechanistically, FoxM1 associates with CBP to activate transcription and with Rb to repress transcription. Although the activating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a61a78742b415dd8733828de4f57e910
https://doi.org/10.1158/0008-5472.c.6514013.v1
https://doi.org/10.1158/0008-5472.c.6514013.v1