Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Bradley J. Maroni"'
Autor:
Youssef M.K. Farag, Kimberly A. Walters, Gabriel Bako, Wolfgang C. Winkelmayer, Kai-Uwe Eckardt, Prabir Roy-Chaudhury, Dennis Vargo, Rajiv Agarwal, Amit Sharma, Mark J. Sarnak, Kunihiro Matsushita, Mark J. Koury, Bruce Spinowitz, Glenn M. Chertow, Wenli Luo, Patrick S. Parfrey, Zeeshan Khawaja, Susan Arnold, Eldrin F. Lewis, Steven K. Burke, Fausto P. Castillo, Alan G. Jardine, Carol Tseng, Bradley J. Maroni, Pablo E. Pergola, Peter A. McCullough, Janet Wittes, Tim Lin, Geoffrey A. Block, James A. Tumlin
Publikováno v:
New England Journal of Medicine. 384:1589-1600
Background Vadadustat is an oral hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitor, a class of drugs that stabilize HIF and stimulate erythropoietin and red-cell production. Meth...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cda62662ef8b66cfe5e7e3470e6d14fd
https://doi.org/10.1056/nejmoa2035938
https://doi.org/10.1056/nejmoa2035938
Autor:
Kimberly A. Walters, Kai-Uwe Eckardt, Zeeshan Khawaja, Mark J. Sarnak, Janet Wittes, Eldrin F. Lewis, Rafal Zwiech, James A. Tumlin, Geoffrey A. Block, Youssef M.K. Farag, Mark J. Koury, Ahmed Awad, Wolfgang C. Winkelmayer, Alan G. Jardine, Dennis Vargo, Bradley J. Maroni, Kunihiro Matsushita, Bruce Spinowitz, Ahmad Aswad, Steven Fishbane, Pablo E. Pergola, Glenn M. Chertow, Wenli Luo, Patrick S. Parfrey, Marcelo R. Bacci, Harold Hubert, Rajiv Agarwal, Peter A. McCullough
Publikováno v:
The New England journal of medicine. 384(17)
Vadadustat is an oral hypoxia-inducible factor prolyl hydroxylase inhibitor, a class of compounds that stimulate endogenous erythropoietin production.We conducted two randomized, open-label, noninferiority phase 3 trials to evaluate the safety and ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::681b9d955a815fcaa6d486042c8af843
https://pubmed.ncbi.nlm.nih.gov/34644481
https://pubmed.ncbi.nlm.nih.gov/34644481
Autor:
Amit Sharma, Emil M. deGoma, Pablo E. Pergola, Geoffrey A. Block, Volker H. Haase, Glenn M. Chertow, Peter A. McCullough, Bradley J. Maroni, Zeeshan Khawaja
Publikováno v:
Nephrology Dialysis Transplantation
Background Vadadustat, an inhibitor of hypoxia-inducible factor prolyl-4-hydroxylase domain dioxygenases, is an oral investigational agent in development for the treatment of anemia secondary to chronic kidney disease. Methods In this open-label Phas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b0ea035de2ab1a1f3c6bb185f667f69
https://doi.org/10.1093/ndt/gfy055
https://doi.org/10.1093/ndt/gfy055
Publikováno v:
Clinical Nephrology
Background: Given regulatory and reimbursement changes in anemia management, we examined hemoglobin variability in a contemporary cohort of maintenance hemodialysis patients. Materials and methods: The study population included > 200,000 hemodialysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bce6d7fbec8c6ac2b1e9c774f0f72a8
https://doi.org/10.5414/cn109031
https://doi.org/10.5414/cn109031
Publikováno v:
American Journal of Nephrology. 45:380-388
Background: Therapeutic options for the treatment of anemia secondary to chronic kidney disease (CKD) remain limited. Vadadustat (AKB-6548) is an oral hypoxia-inducible factor prolyl-hydroxylase domain (HIF-PHD) inhibitor that is being investigated f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42c8b360eed4f08c867131bc114661db
https://doi.org/10.1159/000464476
https://doi.org/10.1159/000464476
Autor:
Bradley J. Maroni, Raimund Hirschberg
Publikováno v:
Seminars in Dialysis. 10:74-81
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9fd13615cdaf1bb7a313d1d6638c41a
https://doi.org/10.1111/j.1525-139x.1997.tb00859.x
https://doi.org/10.1111/j.1525-139x.1997.tb00859.x
Autor:
David Harris, I. E. Priel, Bradley J. Maroni, Mark S. Paller, H. E. Eliahou, Nina E. Tolkoff-Rubin, Andre A. Kaplan
Publikováno v:
Seminars in Dialysis. 7:103-116
Summary With the recent progress in molecular and cellular biology, the 1990s present a unique opportunity for understanding the cellular or humoral factors responsible for accelerated catabolism in ARF. This author believes that a greater priority s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::186b45e0bdb4bcbffa87854a5ed1ce4a
https://doi.org/10.1111/j.1525-139x.1994.tb00818.x
https://doi.org/10.1111/j.1525-139x.1994.tb00818.x
Autor:
John W. Kusek, June Leung, David B. Cockram, Diane Poole, Lata Paranandi, Bradley J. Maroni, Johanna T. Dwyer, Rhoda Makoff, Jerrilynn D. Burrowes, Michael V. Rocco
Publikováno v:
American Journal of Kidney Diseases. 39:245-256
The nutritional status of the first 1,000 patients randomized into the Hemodialysis (HEMO) Study was analyzed at baseline when they received their typical dialysis dose (equilibrated Kt/V = 1.30 +/- 0.22) and dialysis membrane. This is the largest st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ac91a82e1ccf2388e60c19e9c7b80ab
https://doi.org/10.1053/ajkd.2002.30543
https://doi.org/10.1053/ajkd.2002.30543
Autor:
William E. Mitch, Bradley J. Maroni
Publikováno v:
American Journal of Kidney Diseases. 33:176-179
There is abundant evidence that patients with chronic renal failure (CRF), including those treated by hemodialysis or peritoneal dialysis, have evidence of malnutrition with decreased body weight and subnormal values of serum proteins (suggesting a l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1550bdd2020a804ff07700b00f08ab2e
https://doi.org/10.1016/s0272-6386(99)70279-9
https://doi.org/10.1016/s0272-6386(99)70279-9
Autor:
Bradley J. Maroni, William E. Mitch
Publikováno v:
Mineral and Electrolyte Metabolism. 24:285-289
Low-protein diets ameliorate uremic symptoms and some of its metabolic complications. These diets can be used successfully to treat patients with chronic renal failure (CRF) because they are able to activate normal compensatory responses when protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::936ffa6aad24bf569c9ab4d8422e1d4b
https://doi.org/10.1159/000057383
https://doi.org/10.1159/000057383