Výsledky vyhledávání - "Bradley J. Kozel"

Chemical rescue of ΔF508-CFTR in C127 epithelial cells reverses aberrant extracellular pH acidification to wild-type alkalization as monitored by microphysiometry

Autor: Andrew J. Van Alst, Douglas B. Luckie, Robert D. Flood, Marija K. Massey, Aashish A. Shah, Vishal Malhotra, Bradley J. Kozel

Publikováno v: Biochemical and biophysical research communications. 451(4)

Cystic fibrosis (CF) is caused by mutations in the gene for CFTR, a cAMP-activated anion channel expressed in apical membranes of wet epithelia. Since CFTR is permeable to HCO3(-), and may regulate bicarbonate exchangers, it is not surprising evidenc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b26dae1ba38ab2f472ed2662056019a
https://pubmed.ncbi.nlm.nih.gov/25130467

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