Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Bradley J. Berger"'
Autor:
Gloria S. Sivko, Lisa MacDonald, Marianne M. Stanford, Michelle Wright Valderas, Leeladhar Sammatur, Jon O. Rayner, Bradley J. Berger, Genevieve Weir, Rajkannan Rajagopalan
Publikováno v:
npj Vaccines, Vol 4, Iss 1, Pp 1-9 (2019)
NPJ Vaccines
NPJ Vaccines
Anthrax is a serious biological threat caused by pulmonary exposure to aerosolized spores of Bacillus anthracis. Biothrax® (anthrax vaccine adsorbed (AVA)) is the only Food and Drug Administration-licensed vaccine and requires five administrations o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d3af29454d87e7a4569d6f34d161bbc
http://link.springer.com/article/10.1038/s41541-019-0102-z
http://link.springer.com/article/10.1038/s41541-019-0102-z
Autor:
Nicole D. Barabé, Bradley J. Berger, Scott Jager, Robert T. Poirier, William E. Lee, John W. Cherwonogrodzky, Michelle L. Grigat
A subunit vaccine candidate was produced from Brucella suis 145 (biovar 4; expressing both the A antigen of Brucella abortus and the M antigen of Brucella melitensis ). The preparation consisted mostly of polysaccharide (PS; >90% [wt/wt]; both cell-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05cea98c8ae2a779a426c023af6c915d
https://europepmc.org/articles/PMC4248776/
https://europepmc.org/articles/PMC4248776/
Publikováno v:
Journal of Bacteriology. 185:2418-2431
The conversion of ketomethiobutyrate to methionine has been previously examined in a number of organisms, wherein the aminotransferases responsible for the reaction have been found to be members of the Ia subfamily (L. C. Berger, J. Wilson, P. Wood,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7b15956e82772a8f1f11af8a0843a18
https://doi.org/10.1128/jb.185.8.2418-2431.2003
https://doi.org/10.1128/jb.185.8.2418-2431.2003
Publikováno v:
Molecular and Biochemical Parasitology. 118:1-10
The ornithine aminotransferase from Plasmodium falciparum 3D7 was cloned, functionally expressed, and characterized. The gene exists as a single copy in the malarial genome and is located on chromosomes 6/7/8. The deduced amino acid sequence was foun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1756e1f466fa75792089d83c85ddad5
https://doi.org/10.1016/s0166-6851(01)00357-7
https://doi.org/10.1016/s0166-6851(01)00357-7
Publikováno v:
FEMS Microbiology Letters. 165:305-312
Methionine consumed during the synthesis of polyamines can be recycled in most organisms by a unique pathway wherein the final step is the transaminative conversion of alpha-ketomethiobutyrate to methionine (KMAT activity). In the trypanosomatid Crit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b4fcfaf5587d869fb950c7210dfefb9
https://doi.org/10.1111/j.1574-6968.1998.tb13162.x
https://doi.org/10.1111/j.1574-6968.1998.tb13162.x
Autor:
Kevin J. Tracey, Peter C. Ulrich, Xini Zhang, Bradley J. Berger, Marina Bianchi, Carla Cerami
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 675:71-75
A high-performance liquid chromatographic method has been developed for a series of aromatic guanylhydrazones that have demonstrated therapeutic potential as anti-inflammatory agents. The compounds were separated using octadecyl or diisopropyloctyl r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d5a225d7cb7ea6ca93d4f330e4eadd6
https://doi.org/10.1016/0378-4347(95)00346-0
https://doi.org/10.1016/0378-4347(95)00346-0
Publikováno v:
Clinical Pharmacokinetics. 22:163-168
Of the existing techniques, HPLC analysis of pentamidine allows for the most sensitive and rapid screening of clinical samples. However, it is important to test several extraction and chromatographic procedures to determine which system works consist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4afcf72ceb38c880713155d2025dd199
https://doi.org/10.2165/00003088-199222030-00001
https://doi.org/10.2165/00003088-199222030-00001
Autor:
Bradley J. Berger
Publikováno v:
Antimicrobial Agents and Chemotherapy. 44:2540-2542
Twenty-three aminooxy compounds have been examined for their ability to inhibit the growth of the malaria parasite Plasmodium falciparum in vitro. Eight of these compounds were found to have 50% inhibitory concentrations less than 10 μM, with the be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9409fa13d9a79fc2fee2a301999abf6
https://doi.org/10.1128/aac.44.9.2540-2542.2000
https://doi.org/10.1128/aac.44.9.2540-2542.2000
Autor:
Naili Liu, Sorrnchai Looareesuwan, Christine L. Flatt, Bradley J. Berger, Holly L. Hoang, Laura Montes, Bryan G. Yipp, May Ho, Kristine Lee, Tara MacRae, Stephen M. Robbins
Publikováno v:
Infection and immunity. 73(12)
The adhesion of Plasmodium falciparum -infected erythrocytes (IRBCs) to human dermal microvascular endothelial cells (HDMECs) under flow conditions is regulated by a Src family kinase- and alkaline phosphatase (AP)-dependent mechanism. In this study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::679ef43edf68e87057df40be5ef30582
https://pubmed.ncbi.nlm.nih.gov/16299313
https://pubmed.ncbi.nlm.nih.gov/16299313
Autor:
Murray G. Hamilton, Cory Vair, Kendal Weatherby, Pierre Lecavalier, Bradley J. Berger, Paul M. Lundy, Corey Davidson, Ira Hill
Publikováno v:
Toxicology. 208(3)
Anesthetized pigs were injected i.m. with 500 mg HI-6 dichloride (HI-6 2Cl) (1-[[[4-(aminocarbonyl)-pyridinio]methoxy]methyl]-2[(hydroxyimino)methyl]pyridinium dichloride; CAS 34433-31-3)) or the molar equivalent of HI-6 dimethanesulphonate (HI-6 DMS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa31a98900ca06f66d853a5ebe6001e3
https://pubmed.ncbi.nlm.nih.gov/15695025
https://pubmed.ncbi.nlm.nih.gov/15695025