Structural Study of GCDFP-15/gp17 in Disease versus Physiological Conditions Using a Proteomic Approach

Autor: John Guardiola, Peter Tornatore, Brian M. Martin, Emilia Caputo, Ramy Moharram, Bradley J. Thatcher, Alessandra Camarca

Publikováno v: Biochemistry (Easton) 42 (2003): 6169–6178. doi:10.1021/bi034038a
info:cnr-pdr/source/autori:Caputo E, Camarca A, Moharram R, Tornatore P, Thatcher B, Guardiola J and Martin BM/titolo:Structural study of GCDFP-15%2Fgp17 in disease versus physiological conditions using a proteomic approach/doi:10.1021%2Fbi034038a/rivista:Biochemistry (Easton)/anno:2003/pagina_da:6169/pagina_a:6178/intervallo_pagine:6169–6178/volume:42

Gross cystic disease fluid protein (GCDFP-15), also known as prolactin-inducible protein (PIP), is a specific breast tumor marker. GCDFP-15/PIP is also identified as gp17 and/or seminal actin-binding protein (SABP) from seminal vesicles and as extrap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2580eb1c62cd731de0d0a5ac47d0c3ba
https://doi.org/10.1021/bi034038a

Glutamate dehydrogenase from liver of euthermic and hibernating Richardson's ground squirrels: Evidence for two distinct enzyme forms

Autor: Bradley J Thatcher, Kenneth B Storey

Publikováno v: Biochemistry and Cell Biology. 79:11-19

Glutamate dehydrogenase (GDH) was purified to homogeneity from the liver of euthermic (37°C body temperature) and hibernating (torpid, 5°C body temperature) Richardson's ground squirrels (Spermophilus richardsonii). SDS-PAGE yielded a subunit molec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5ef1cd6fc63c168585878999641650d4
https://doi.org/10.1139/o00-086

Acetylation of Novel Sites in the Nucleosomal Binding Domain of Chromosomal Protein HMG-14 by p300 Alters Its Interaction with Nucleosomes

Autor: Julio E. Herrera, Michael Bustin, Bradley J. Thatcher, Alex Vassilev, Yoshihiro Nakatani, Michael Bergel, Brian Martin, Marta Prymakowska-Bosak

Publikováno v: Journal of Biological Chemistry. 275:11514-11520

The reversible acetylation of histones is associated with structural alterations in the chromatin fiber that affect various DNA-related activities. Here we show that the histone acetyltransferase p300 specifically acetylates HMG-14, a nonhistone stru

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6771026401a341723af2446e0a872ef8
https://doi.org/10.1074/jbc.275.15.11514

Biomarker discovery

Autor: Emilia Caputo, Bradley J. Thatcher

Publisher Summary Biomarkers are tools for the diagnosis, monitoring of therapy, and screening for a number of diseases. Biomarkers can also be used to detect disease risk factors allowing the physician to recommend or prescribe more intensive monito

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b1a8359bb649bdb00edcdb1e1e9bba1b
https://doi.org/10.1016/b978-044451980-1.50024-0

The characterization and purification of a human transcription factor modulating the glutathione peroxidase gene in response to oxygen tension

Autor: Frank, Merante, Svetlana M, Altamentova, Donald A G, Mickle, Richard D, Weisel, Bradley J, Thatcher, Brian M, Martin, John G, Marshall, Laura C, Tumiati, Douglas B, Cowan, Ren-Ke, Li

Publikováno v: Molecular and cellular biochemistry. 229(1-2)

An oxygen responsive transcription factor regulating human glutathione peroxidase gene (GPx) through two oxygen responsive elements (ORE I and ORE2) has been purified and characterized by sequence-specific DNA affinity chromatography. The DNA binding

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d56e62c98ae93c6a1cfc644d96eb1cdc
https://pubmed.ncbi.nlm.nih.gov/11936849