Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Bradley G. Magor"'
Autor:
Heather Fifield, Maribel Berru, Justin J. King, Stephanie C. Tucker, Matthew Quinlan, Alex M. Dancyger, Holly L. Saunders, Bradley G. Magor, Mani Larijani, Alberto Martin
Publikováno v:
The FASEB Journal. 26:1517-1525
Activation-induced cytidine deaminase (AID) mediates antibody diversification by deaminating deoxycytidines to deoxyuridine within immunoglobulin genes. However, it also generates genome-wide DNA lesions, leading to transformation. Though the biochem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38e3ff85c7fa553d8d7cd60acc9c408c
https://doi.org/10.1096/fj.11-198135
https://doi.org/10.1096/fj.11-198135
Publikováno v:
Immunology Today. 20:13-17
Based on comparisons of the structure and transcriptional regulation of the IgH locus in mammals and a bony fish, Brad Magor and colleagues present a hypothesis in which enhancer evolution was the driving force in (and a prerequisite for) the develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15838c5211443fb306397ae1d40f108c
https://doi.org/10.1016/s0167-5699(98)01380-2
https://doi.org/10.1016/s0167-5699(98)01380-2
Characterization of Oct2 from the Channel Catfish: Functional Preference for a Variant Octamer Motif
Autor:
David A. Ross, Bradley G. Magor, Darlene L. Middleton, Melanie R. Wilson, Norman W. Miller, L. William Clem, Gregory W. Warr
Publikováno v:
The Journal of Immunology. 160:3874-3882
The Ig heavy chain enhancer of the channel catfish (Ictalurus punctatus) has an unusual position and structure, being found in the 3′ region of the μ gene and containing eight functional octamer motifs of consensus (ATGCAAAT) and variant sequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c4d7a6233c71b40e62466b4dead85bf
https://doi.org/10.4049/jimmunol.160.8.3874
https://doi.org/10.4049/jimmunol.160.8.3874
Publikováno v:
Immunogenetics. 51(8-9)
The organization of immunoglobulin heavy (H) chain genes in teleosts resembles that of mammals and amphibians, whereas light (L) chain genes are arranged in multiple clusters of variable (VL), joining (JL), and constant (CL) region segments. Sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd172cec5c0adc7a0a4b378046457782
https://pubmed.ncbi.nlm.nih.gov/10941836
https://pubmed.ncbi.nlm.nih.gov/10941836
Autor:
Darlene A. Middleton, Gregory W. Warr, Melanie Wilson, Michelle Lyles, Barry E. Ledford, Bradley G. Magor, L. William Clem, David Ross, Norman W. Miller
Publikováno v:
Developmental and comparative immunology. 23(3)
The DNA-binding (POU) domain of the catfish Oct2 transcription factor was shown, by electromobility shift assays and surface plasmon resonance techniques, to have an affinity for the consensus octamer motif (ATGCAAAT) that was slightly higher than it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cba45bd6fa4e51d42a3124421c191e8
https://pubmed.ncbi.nlm.nih.gov/10402207
https://pubmed.ncbi.nlm.nih.gov/10402207
Publikováno v:
Immunogenetics. 46(3)
bstract The transcriptional enhancer (Eμ3′) within the Ig heavy chain (IgH) locus of the channel catfish differs from those found in mammalian IgH loci in both its location and structure. However, upon transfection into fish or mouse lymphocytes,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21972eba8d2def1e372cb05d25984c8e
https://pubmed.ncbi.nlm.nih.gov/9211744
https://pubmed.ncbi.nlm.nih.gov/9211744
Autor:
Darlene L. Middleton, David Ross, Norman W. Miller, L. William Clem, Gregory W. Warr, Bradley G. Magor, Melanie Wilson
Publikováno v:
Developmental & Comparative Immunology. 21:95
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a620a432fdf4c3d40aeb0808acb48bc7
https://doi.org/10.1016/s0145-305x(97)88527-8
https://doi.org/10.1016/s0145-305x(97)88527-8