Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Bradley D. Winters"'
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract Principal neurons (PNs) of the lateral superior olive nucleus (LSO) in the brainstem of mammals compare information between the two ears and enable sound localization on the horizontal plane. The classical view of the LSO is that it extracts
Externí odkaz:
https://doaj.org/article/59d31bdfd8af4fb489cbc3026d659ad9
Publikováno v:
J Comp Neurol
Sound localization critically relies on brainstem neurons that compare information from the two ears. The conventional role of the lateral superior olive (LSO) is extraction of intensity differences; however, it is increasingly clear that relative ti
Autor:
Mingyan Zhu, Gary A. Wayman, Soren Impey, Crystal Dillon, Talley J. Lambert, Gulcan Semra Sahin, Suzanne M. Appleyard, Hiroko Shiina, Matasha Dhar, Bradley D. Winters
Publikováno v:
Mol Cell Neurosci
Normal development of neuronal connections in the hippocampus requires neurotrophic signals, including the cytokine leptin. During neonatal development, leptin induces formation and maturation of dendritic spines, the main sites of glutamatergic syna
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 37(12)
The principal neurons of the medial superior olive (MSO) encode cues for horizontal sound localization through comparisons of the relative timing of EPSPs. To understand how the timing and amplitude of EPSPs are maintained during propagation in the d
Autor:
Alok De, Éva Szentirmai, Christopher J. Davis, Ping Taishi, James M. Clinton, Bradley D. Winters, James M. Krueger, Mark R. Zielinski
Publikováno v:
Journal of Applied Physiology. 109:1318-1327
Sleep is dependent upon prior brain activities, e.g., after prolonged wakefulness sleep rebound occurs. These effects are mediated, in part, by humoral sleep regulatory substances such as cytokines. However, the property of wakefulness activity that
Autor:
Nace L. Golding, Bradley D. Winters
Publikováno v:
Neuron. 98:166-178.e2
Summary Utilization of timing-based sound localization cues by neurons in the medial superior olive (MSO) depends critically on glycinergic inhibitory inputs. After hearing onset, the strength and subcellular location of these inhibitory inputs are d
Autor:
Yanhua H. Huang, Bradley D. Winters, Masago Ishikawa, Mami Otaka, Oliver M. Schlüter, Anthony A. Grace, Yan Dong, Peter A. Neumann
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 33(16)
As a classic neuromodulator, dopamine has long been thought to modulate, rather than trigger, synaptic plasticity. In contrast, our present results demonstrate that within the parallel projections of dopaminergic and GABAergic terminals from the vent
Autor:
James M. Krueger, Yanhua H. Huang, Juliane M. Krüger, Bradley D. Winters, Krzysztof Czaja, Yan Dong, Oliver M. Schlüter, Masago Ishikawa, Zachary R. Gallaher, Xiaojie Huang
Endocannabinoid signaling critically regulates emotional and motivational states via activation of cannabinoid receptor 1 (CB1) in the brain. The nucleus accumbens (NAc) functions to gate emotional and motivational responses. Although expression of C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d54a2e2bb3dad0ddb403b8d02f7fb18f
https://europepmc.org/articles/PMC3479600/
https://europepmc.org/articles/PMC3479600/
Autor:
James M. Krueger, James M. Clinton, Kathryn A. Jewett, Bradley D. Winters, Christopher J. Davis, Ping Taishi, Mark R. Zielinski
Publikováno v:
Progress in brain research. 193
Cytokines such as tumor necrosis factor alpha (TNFα) and interleukin-1 beta (IL1β) play a role in sleep regulation in health and disease. TNFα or IL1β injection enhances non-rapid eye movement sleep. Inhibition of TNFα or IL1β reduces spontaneo