Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Bradley C. Logsdon"'
Autor:
Gheorghe Proteasa, Bradley C. Logsdon, Jay I. Koepke, Stanley R. Terlecky, Thomas C. Merigan, Mark A. Winters, Ladislau C. Kovari, Philip D. Martin, Zdzislaw Wawrzak, John F. Vickrey
Publikováno v:
Journal of Virology. 78:3123-3132
The goal of this study was to use X-ray crystallography to investigate the structural basis of resistance to human immunodeficiency virus type 1 (HIV-1) protease inhibitors. We overexpressed, purified, and crystallized a multidrug-resistant (MDR) HIV
Autor:
Robert A. Jacobson, Robert J. Angelici, Ilia A. Guzei, Michael A. Reynolds, Bradley C. Logsdon, Leonard M. Thomas
Publikováno v:
Organometallics. 18:4075-4081
Ultraviolet photolysis of hexanes solutions containing the complexes M(CO){sub 6} (M = Cr, Mo, W) or CpMn(CO){sub 3}(Cp = {eta}{sup 5}{minus}C{sub 5}H{sub 5}) and excess thiophene (T*)(T* = 2,5-dimethylthiophene (2,5-Me{sub 2}T), benzothiophene (BT),
Autor:
Gheorghe Proteasa, Mark A. Winters, Bradley C. Logsdon, John F. Vickrey, Thomas C. Merigan, Ladislau C. Kovari, Sarah Palmer
Publikováno v:
Protein expression and purification. 28(1)
High-resolution X-ray crystallographic structures of HIV-1 protease clinical variants complexed with licensed inhibitors are essential to understanding the fundamental cause of protease drug resistance. There is a need for structures of naturally evo