Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Bradley Brasher"'
Autor:
David S. Hewings, Johanna Heideker, Taylur P. Ma, Andrew P. AhYoung, Farid El Oualid, Alessia Amore, Gregory T. Costakes, Daniel Kirchhofer, Bradley Brasher, Thomas Pillow, Nataliya Popovych, Till Maurer, Carsten Schwerdtfeger, William F. Forrest, Kebing Yu, John Flygare, Matthew Bogyo, Ingrid E. Wertz
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Deubiquitinases are proteases that cleave after the C-terminus of ubiquitin to hydrolyze ubiquitin chains and cleave ubiquitin from substrates. Here the authors describe a reactive-site-centric chemoproteomics approach to studying deubiquitinase acti
Externí odkaz:
https://doaj.org/article/a36fd9ead45149f0b851c7d214b80597
Autor:
Barbara Wojciechowski, Ralph Ward, Paul Bradley Brasher, Christopher G. Slatore, Gerard A. Silvestri, Mulugeta Gebregziabher, Nichole T. Tanner
Publikováno v:
Chest. 158:1742-1752
Background Adherence to annual low-dose CT was 95% in the National Lung Screening Trial and must be replicated to achieve mortality benefit from screening. Research Question How do we determine adherence rates within the Veterans Affairs Lung Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcded574b3ca1e21a9f7be7040c1249f
https://doi.org/10.1016/j.chest.2020.04.063
https://doi.org/10.1016/j.chest.2020.04.063
Publikováno v:
Clinical Lung Cancer. 21:e89-e98
Introduction The field of biomarker development is evolving to assist in determining benign from malignant pulmonary nodules. Although a prospective clinical utility would best to show how a biomarker affects patient treatment and outcomes, we sought
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4d324d05532df24b0763765708a762b
https://doi.org/10.1016/j.cllc.2019.05.004
https://doi.org/10.1016/j.cllc.2019.05.004
Proteomics of broad deubiquitylase inhibition unmasks redundant enzyme function to reveal substrates
Autor:
Randall W. King, Joel M. Chick, Bradley Brasher, Steven P. Gygi, Joao A. Paulo, Valentina Rossio
Deubiquitylating enzymes (DUBs) counteract ubiquitylation to control stability or activity of substrates. Identification of DUB substrates is challenging because multiple DUBs act on the same substrates, thwarting genetic approaches. Here, we circumv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c15379efdb06e01209912531db6c7236
https://doi.org/10.1101/844811
https://doi.org/10.1101/844811
Autor:
Rahul G. Argula, Amit Chopra, Sidharth Navin Jogani, Adam Austin, John T. Huggins, Paul Bradley Brasher
Publikováno v:
The American journal of the medical sciences. 354(1)
Urinothorax is an uncommon thoracic complication of genitourinary (GU) tract disease, which is most frequently caused by obstructive uropathy, but may also occur as a result of iatrogenic or traumatic GU injury. It is underrecognized because of a per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a7906dc0e6dc1f8181da1781eef23d0
https://pubmed.ncbi.nlm.nih.gov/28755732
https://pubmed.ncbi.nlm.nih.gov/28755732
Publikováno v:
Chest. 154:636A-637A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a048e9cd9bcb67e01e60976353c0aaeb
https://doi.org/10.1016/j.chest.2018.08.576
https://doi.org/10.1016/j.chest.2018.08.576
Publikováno v:
Biochemistry. 46(35)
Factor XIII can be activated proteolytically by thrombin cleavage of the activation peptide or non-proteolytically by exposure to 50 mM Ca2+. The resultant transglutaminase cross-links Q and K residues within the noncovalently associated fibrin clot.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a51122773f299ff1833dff30ebbbfd70
https://pubmed.ncbi.nlm.nih.gov/17691819
https://pubmed.ncbi.nlm.nih.gov/17691819