Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Bradley Austin"'
Autor:
Mona Hersi, Andrew Beck, Candyce Hamel, Leila Esmaeilisaraji, Kusala Pussegoda, Bradley Austin, Nadera Ahmadzai, Misty Pratt, Micere Thuku, Fatemeh Yazdi, Alexandria Bennett, Nicole Shaver, Niyati Vyas, Becky Skidmore, Brian Hutton, Douglas Manuel, Matt Morrow, Smita Pakhale, Justin Presseau, Beverley J. Shea, Julian Little, David Moher, Adrienne Stevens
Publikováno v:
Systematic Reviews, Vol 13, Iss 1, Pp 1-33 (2024)
Abstract Background This overview of reviews aims to identify evidence on the benefits (i.e. tobacco use abstinence and reduction in smoking frequency) and harms (i.e. possible adverse events/outcomes) of smoking cessation interventions among adults
Externí odkaz:
https://doaj.org/article/593731ea210c4df5a6fd69f6a2789d39
Autor:
Stephen Boulton, Joanna Poutou, Rida Gill, Nouf Alluqmani, Xiaohong He, Ragunath Singaravelu, Mathieu J.F. Crupi, Julia Petryk, Bradley Austin, Leonard Angka, Zaid Taha, Iris Teo, Siddarth Singh, Rameen Jamil, Ricardo Marius, Nikolas Martin, Taylor Jamieson, Taha Azad, Jean-Simon Diallo, Carolina S. Ilkow, John C. Bell
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 31, Iss , Pp 101110- (2023)
SARS-CoV-2, the etiological agent behind the coronavirus disease 2019 (COVID-19) pandemic, has continued to mutate and create new variants with increased resistance against the WHO-approved spike-based vaccines. With a significant portion of the worl
Externí odkaz:
https://doaj.org/article/3db94dba202d4816898f54399e85392a
Autor:
John Bell, Sydney Vallati, Mathieu Crupi, Zaid Taha, Julia Petryk, Bradley Austin, Victoria Gilchrist, Nouf Alluqmani, Stephen Boulton
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/38904a624b764fcb97f7da0b1cd48d90
Autor:
Abera Surendran, Monire Jamalkhah, Joanna Poutou, Rayanna Birtch, Christine Lawson, Jaahnavi Dave, Mathieu J. F. Crupi, Justin Mayer, Victoria Taylor, Julia Petryk, Christiano Tanese de Souza, Neil Moodie, Jacob Lecompte Billingsley, Bradley Austin, Nicole Cormack, Natalie Blamey, Reza Rezaei, Curtis W. McCloskey, Emily E. F. Fekete, Harsimrat K. Birdi, Serge Neault, Taylor R. Jamieson, Brenna Wylie, Sarah Tucker, Taha Azad, Barbara Vanderhyden, Lee-Hwa Tai, John C. Bell, Carolina S. Ilkow
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionAdipocytes in the tumour microenvironment are highly dynamic cells that have an established role in tumour progression, but their impact on anti-cancer therapy resistance is becoming increasingly difficult to overlook.MethodsWe investigat
Externí odkaz:
https://doaj.org/article/6f4b17f759de414f8da10ac2aa3a216f
Autor:
Marie-Eve Wedge, Victoria A. Jennings, Mathieu J. F. Crupi, Joanna Poutou, Taylor Jamieson, Adrian Pelin, Giuseppe Pugliese, Christiano Tanese de Souza, Julia Petryk, Brian J. Laight, Meaghan Boileau, Zaid Taha, Nouf Alluqmani, Hayley E. McKay, Larissa Pikor, Sarwat Tahsin Khan, Taha Azad, Reza Rezaei, Bradley Austin, Xiaohong He, David Mansfield, Elaine Rose, Emily E. F. Brown, Natalie Crawford, Almohanad Alkayyal, Abera Surendran, Ragunath Singaravelu, Dominic G. Roy, Gemma Migneco, Benjamin McSweeney, Mary Lynn Cottee, Egon J. Jacobus, Brian A. Keller, Takafumi N. Yamaguchi, Paul C. Boutros, Michele Geoffrion, Katey J. Rayner, Avijit Chatterjee, Rebecca C. Auer, Jean-Simon Diallo, Derrick Gibbings, Benjamin R. tenOever, Alan Melcher, John C. Bell, Carolina S. Ilkow
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
RNA-based viruses can be engineered to express artificial microRNAs (amiRNAs). Here, the authors identify a candidate amiRNA that confers a replicative advantage to oncolytic viruses, enhancing their anticancer potency, and show that intercellular tr
Externí odkaz:
https://doaj.org/article/4c63ee51ae0d403a99532dab542cb349
Autor:
Jack T. Whelan, Ragunath Singaravelu, Fuan Wang, Adrian Pelin, Levi A. Tamming, Giuseppe Pugliese, Nikolas T. Martin, Mathieu J. F. Crupi, Julia Petryk, Bradley Austin, Xiaohong He, Ricardo Marius, Jessie Duong, Carter Jones, Emily E. F. Fekete, Nouf Alluqmani, Andrew Chen, Stephen Boulton, Michael S. Huh, Matt Y. Tang, Zaid Taha, Elena Scut, Jean-Simon Diallo, Taha Azad, Brian D. Lichty, Carolina S. Ilkow, John C. Bell
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Poxvirus vectors represent versatile modalities for engineering novel vaccines and cancer immunotherapies. In addition to their oncolytic capacity and immunogenic influence, they can be readily engineered to express multiple large transgenes. However
Externí odkaz:
https://doaj.org/article/f7cfd3f77d384dec8678da5baade9481
Autor:
Mathieu J. F. Crupi, Zaid Taha, Thijs J. A. Janssen, Julia Petryk, Stephen Boulton, Nouf Alluqmani, Anna Jirovec, Omar Kassas, Sarwat T. Khan, Sydney Vallati, Emily Lee, Ben Zhen Huang, Michael Huh, Larissa Pikor, Xiaohong He, Ricardo Marius, Bradley Austin, Jessie Duong, Adrian Pelin, Serge Neault, Taha Azad, Caroline J. Breitbach, David F. Stojdl, Michael F. Burgess, Scott McComb, Rebecca Auer, Jean-Simon Diallo, Carolina S. Ilkow, John Cameron Bell
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Colorectal cancer is the third most diagnosed cancer and the second leading cause of cancer mortality worldwide, highlighting an urgent need for new therapeutic options and combination strategies for patients. The orchestration of potent T cell respo
Externí odkaz:
https://doaj.org/article/29d21675c815413ebbf0f96fc31a0567
Autor:
Nikolas T. Martin, Mathieu J. F. Crupi, Zaid Taha, Joanna Poutou, Jack T. Whelan, Sydney Vallati, Julia Petryk, Ricardo Marius, Bradley Austin, Taha Azad, Mason Boulanger, Tamara Burgess, Ilson Sanders, Camille Victoor, Bryan C. Dickinson, Jean-Simon Diallo, Carolina S. Ilkow, John C. Bell
Publikováno v:
Pharmaceuticals, Vol 16, Iss 5, p 709 (2023)
The approval of different cytokines as anti-neoplastic agents has been challenged by dose-limiting toxicities. Although reducing dose levels affords improved tolerability, efficacy is precluded at these suboptimal doses. Strategies combining cytokine
Externí odkaz:
https://doaj.org/article/390661383464430eafc22cdd62a9b18f
Autor:
Danielle Rice, Kimberly Corace, Dianna Wolfe, Leila Esmaeilisaraji, Alan Michaud, Alicia Grima, Bradley Austin, Reuben Douma, Pauline Barbeau, Claire Butler, Melanie Willows, Patricia A Poulin, Beth A Sproule, Amy Porath, Gary Garber, Sheena Taha, Gord Garner, Becky Skidmore, David Moher, Kednapa Thavorn, Brian Hutton
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0244401 (2020)
BackgroundGuidelines recommend that individuals with opioid use disorder (OUD) receive pharmacological and psychosocial interventions; however, the most appropriate psychosocial intervention is not known. In collaboration with people with lived exper
Externí odkaz:
https://doaj.org/article/e6d86b4f8218476d8c52dee8b1f0289a
Autor:
Emily E. F. Brown, Reza Rezaei, Taylor R. Jamieson, Jaahnavi Dave, Nikolas T. Martin, Ragunath Singaravelu, Mathieu J. F. Crupi, Stephen Boulton, Sarah Tucker, Jessie Duong, Joanna Poutou, Adrian Pelin, Hamed Yasavoli-Sharahi, Zaid Taha, Rozanne Arulanandam, Abera Surendran, Mina Ghahremani, Bradley Austin, Chantal Matar, Jean-Simon Diallo, John C. Bell, Carolina S. Ilkow, Taha Azad
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5, p 2268 (2021)
Despite sequence similarity to SARS-CoV-1, SARS-CoV-2 has demonstrated greater widespread virulence and unique challenges to researchers aiming to study its pathogenicity in humans. The interaction of the viral receptor binding domain (RBD) with its
Externí odkaz:
https://doaj.org/article/59fc22ade87647bda7775d3c06fcf384