Zobrazeno 1 - 10
of 233
pro vyhledávání: '"Bradley A, Maron"'
Autor:
Lu Pan, Paolo Parini, Roman Tremmel, Joseph Loscalzo, Volker M. Lauschke, Bradley A. Maron, Paola Paci, Ingemar Ernberg, Nguan Soon Tan, Zehuan Liao, Weiyao Yin, Sundararaman Rengarajan, Xuexin Li, The SCA Consortium
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-21 (2024)
Abstract Single-cell sequencing datasets are key in biology and medicine for unraveling insights into heterogeneous cell populations with unprecedented resolution. Here, we construct a single-cell multi-omics map of human tissues through in-depth cha
Externí odkaz:
https://doaj.org/article/bfac2c6a06f6422a8ceb3444a8f601fb
Autor:
Bradley A. Maron, Rui-Sheng Wang, Sergei Shevtsov, Stavros G. Drakos, Elena Arons, Omar Wever-Pinzon, Gordon S. Huggins, Andriy O. Samokhin, William M. Oldham, Yasmine Aguib, Magdi H. Yacoub, Ethan J. Rowin, Barry J. Maron, Martin S. Maron, Joseph Loscalzo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-4 (2024)
Externí odkaz:
https://doaj.org/article/50603cd66e7949c081913418f58fccd7
Iatrogenic esophageal dysmotility as a barrier to transplantation in pulmonary arterial hypertension
Autor:
Michael S. Miller, Shelsey W. Johnson, Alexander R. Opotowsky, Michael J. Landzberg, Nirmal S. Sharma, Hilary J. Goldberg, Alexandra K. Wong, Alison S. Witkin, Josanna Rodriguez-Lopez, Ronald H. Goldstein, Bradley A. Maron, Bradley M. Wertheim
Publikováno v:
JHLT Open, Vol 5, Iss , Pp 100098- (2024)
Esophageal dysmotility is identified as a contraindication to lung transplantation at some centers due to increased risks of acute rejection, pulmonary infection, and chronic lung allograft dysfunction. Phosphodiesterase-type 5 inhibitors (PDE5i) are
Externí odkaz:
https://doaj.org/article/4145d27170eb4e76b982c3e6fb360f36
Autor:
Shelsey W. Johnson, Rui-Sheng Wang, Michael R. Winter, Kari R. Gillmeyer, Katarina Zeder, Elizabeth S. Klings, Ronald H. Goldstein, Renda Soylemez Wiener, Bradley A. Maron
Publikováno v:
ERJ Open Research, Vol 10, Iss 3 (2024)
Background Clinical trials repurposing pulmonary arterial hypertension (PAH) therapies to patients with lung disease- or hypoxia-pulmonary hypertension (PH) (classified as World Health Organization Group 3 PH) have failed to show a consistent benefit
Externí odkaz:
https://doaj.org/article/19d8d7068a8744eb8e1d67da7977ec40
Autor:
Allan Lawrie, Kelly Chin, Yiu‐Lian Fong, Cynthia Gargano, Xavier Gitton, Cheng He, David G. Kiely, Li Zhou, Lihan Zhou, Bradley A. Maron, Debbie Quinn, Stephan Rosenkranz, Dimitri Stamatiadis, Mark Toshner, Martin R. Wilkins, Luke Howard, Ioana R. Preston
Publikováno v:
Pulmonary Circulation, Vol 14, Iss 2, Pp n/a-n/a (2024)
Abstract A blood test identifying patients at increased risk of pulmonary hypertension (PH) could streamline the investigative pathway. The prospective, multicenter CIPHER study aimed to develop a microRNA‐based signature for detecting PH in breath
Externí odkaz:
https://doaj.org/article/b8ab45400a204fd294105f2eb5f0f631
Autor:
Arun Jose, Natalia Rahman, Alexander R. Opotowsky, Thomas J. Glorioso, Stephen W. Waldo, Katarina Zeder, Arnold Seto, Jean M. Elwing, Francis X. McCormack, Bradley A. Maron
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 8 (2024)
Background Portopulmonary hypertension (PoPH), associated with increased mortality, can limit treatment options for liver diseases. Data on the continuum of clinical risk related to cardiopulmonary hemodynamics in PoPH are lacking. Methods and Result
Externí odkaz:
https://doaj.org/article/1ce38369721842aea7debe9d8e7b5a8f
Autor:
George A. Alba, Iris Y. Zhou, Molly Mascia, Michael Magaletta, Jehan W. Alladina, Francesca L. Giacona, Leo C. Ginns, Peter Caravan, Bradley A. Maron, Sydney B. Montesi
Publikováno v:
Pulmonary Circulation, Vol 14, Iss 1, Pp n/a-n/a (2024)
Abstract Compared to healthy volunteers, participants with post‐acute sequelae of SARS‐CoV‐2 infection (PASC) demonstrated increased plasma levels of the prothrombotic protein NEDD9, which associated inversely with indices of pulmonary vascular
Externí odkaz:
https://doaj.org/article/12422b0881fd4dc08ae772bf641eb802
Autor:
Bradley A. Maron
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 8 (2023)
The definition of pulmonary hypertension (PH) has changed recently based, in part, on contemporary outcome data and to focus on early disease detection. Now, PH includes patients with mean pulmonary artery pressure >20 mm Hg measured by right heart c
Externí odkaz:
https://doaj.org/article/5c61b8e0225d4aa28d2102ba261643be
Autor:
Jingyi Gong, Renata R.T. Castro, Jesse P. Caron, Camden P. Bay, Jon Hainer, Alexander R. Opotowsky, Mandeep R. Mehra, Bradley A. Maron, Marcelo F. Di Carli, John D. Groarke, Anju Nohria
Publikováno v:
ESC Heart Failure, Vol 9, Iss 1, Pp 293-302 (2022)
Abstract Aims The minute ventilation–carbon dioxide production relationship (VE/VCO2 slope) is widely used for prognostication in heart failure (HF) with reduced left ventricular ejection fraction (LVEF). This study explored the prognostic value of
Externí odkaz:
https://doaj.org/article/16c37a3e15ac43a79a3af53a5092e9a3
Autor:
Bradley M. Wertheim, Rui-Sheng Wang, Christelle Guillermier, Christiane V.R. Hütter, William M. Oldham, Jörg Menche, Matthew L. Steinhauser, Bradley A. Maron
Publikováno v:
JCI Insight, Vol 8, Iss 4 (2023)
In pulmonary arterial hypertension (PAH), inflammation promotes a fibroproliferative pulmonary vasculopathy. Reductionist studies emphasizing single biochemical reactions suggest a shift toward glycolytic metabolism in PAH; however, key questions rem
Externí odkaz:
https://doaj.org/article/3241f24b97504570a5420e07c730d523