Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Bradleigh E. Navalsky"'
Autor:
Kyle B. Matchett, Terence R.J. Lappin, Tejvir S. Khurana, Melanie J. Percy, Abigail W. Bigham, Bradleigh E. Navalsky, Daisheng Song, Reinhold J. Medina, James S. O. McCullagh, Wei Guan, Cassandra Ingersoll, John Walsby-Tickle, Frank S. Lee, Emanuele Loro, Lydia Eeles, Tao Wang
Publikováno v:
Proc Natl Acad Sci U S A
Tibetans have adapted to the chronic hypoxia of high altitude and display a distinctive suite of physiologic adaptations, including augmented hypoxic ventilatory response and resistance to pulmonary hypertension. Genome-wide studies have consistently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e597d2d2c1f5d5e61d23745b86ae830
https://europepmc.org/articles/PMC7275716/
https://europepmc.org/articles/PMC7275716/
Autor:
Alexander P.A. Stegmann, Bradleigh E. Navalsky, Albertine E. Donker, Richard van Wijk, Kai Peng, Wei Guan, Frank S. Lee, Daisheng Song, Margje Sinnema, Johanna W. H. Janssen
Publikováno v:
Blood, 132(13), 1455-1458. The American Society of Hematology
TO THE EDITOR: Mutations in the EGLN1 (also known as PHD2 ) gene are associated with erythrocytosis.[1][1] The encoded protein, PHD2, is a central cellular oxygen sensor that hydroxylates the α subunit of the hypoxia inducible factor (HIF) transcrip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6efc2cb3dc3ce2381c0455a0c385ae0a
https://doi.org/10.1182/blood-2018-06-854711
https://doi.org/10.1182/blood-2018-06-854711
Autor:
Marian Bergkamp, Patrick R. Arsenault, Paul M. Lieberman, Andrew M. Ravaschiere, Daisheng Song, Bradleigh E. Navalsky, Frank S. Lee
Publikováno v:
ChemBioChem. 17:2316-2323
The prolyl hydroxylase domain (PHD) protein:hypoxia inducible factor (HIF) pathway is the main pathway by which changes in oxygen concentration are transduced to changes in gene expression. In mammals, there are three PHD paralogues, and PHD2 has eme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a797f934be38adb0e1ef207a8bd39b8c
https://doi.org/10.1002/cbic.201600493
https://doi.org/10.1002/cbic.201600493
Publikováno v:
Conservation Genetics; Aug2022, Vol. 23 Issue 4, p853-858, 6p
Identification of Small-Molecule PHD2 Zinc Finger Inhibitors that Activate Hypoxia Inducible Factor.
Autor:
Arsenault, Patrick R., Song, Daisheng, Bergkamp, Marian, Ravaschiere, Andrew M., Navalsky, Bradleigh E., Lieberman, Paul M., Lee, Frank S.
Publikováno v:
ChemBioChem; 12/14/2016, Vol. 17 Issue 24, p2316-2323, 8p