Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Bradford Siegele"'
Autor:
Daniel Martin, Maria S. Degese, Lynn Vitale-Cross, Ramiro Iglesias-Bartolome, Juan Luis Callejas Valera, Zhiyong Wang, Xiaodong Feng, Huwate Yeerna, Vachan Vadmal, Toshiro Moroishi, Rick F. Thorne, Moraima Zaida, Bradford Siegele, Sok C. Cheong, Alfredo A. Molinolo, Yardena Samuels, Pablo Tamayo, Kun Liang Guan, Scott M. Lippman, J. Guy Lyons, J. Silvio Gutkind
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Dysregulation of the Hippo signaling is a frequent event in human malignancies, but the molecular mechanisms remain unclear. Here the authors show that in head and neck squamous carcinoma, FAT1 interacts with the Hippo signaling complex, resulting in
Externí odkaz:
https://doaj.org/article/1b930320d9074414b8a21037b5706075
Autor:
Justin A Bishop, Lester D R Thompson, Bradford Siegele, Jeffrey Gagan, Mena Mansour, Rebecca D Chernock, Lisa M Rooper
Publikováno v:
Histopathology. 82:305-313
Mucoepidermoid carcinoma (MEC) is historically defined by a mix of squamoid, intermediate, and mucous cells, but we have recently encountered several cases lacking immunoreactivity for squamous markers p40, p63, and CK5/6 despite MAML2 fusions. This
Publikováno v:
Pediatric Blood & Cancer. 69
Autor:
Gabriel Ramos‐Gonzalez, Robert Crum, Alec Allain, Timna Agur, Laura O’Melia, Steven Staffa, Sandra K. Burchett, Bradford Siegele, Olga Weinberg, Nancy M. Rodig, Rima Fawaz, Tajinder P Singh, Dawn A. Freiberger, Heung Bae Kim
Publikováno v:
Pediatric Transplantation. 26
This study aimed to characterize features present at the time of diagnosis and describe outcomes in patients with post-transplant lymphoproliferative disorder (PTLD) following pediatric solid organ transplantation.We performed a retrospective review
Autor:
Grzegorz Nalepa, Etan Orgel, Richard H. Ho, Matthew J. Oberley, Mark D. Fleming, Yves D. Pastore, Courtney D. DiNardo, Joseph Rosenthal, M. Tarek Elghetany, Akiko Shimamura, Maggie Malsch, Bradford Siegele, Ashley Galvin, Michelle Manalang, Elissa Furutani, Iftikhar Hanif, James A. Connelly, Jordan Henry Larson, Nicole Karras, Lauri Burroughs, Edie Weller, Farid Boulad, Kasiani C. Myers, Blanche P. Alter, Carlos E. Bueso-Ramos, Maxim Norkin, Valérie Arsenault, Taizo A. Nakano, Kelly Walkovich, Lisa J. McReynolds, Stella M. Davies, Paul Castillo
Publikováno v:
Lancet Haematol
Summary Background Data to inform surveillance and treatment for leukaemia predisposition syndromes are scarce and recommendations are largely based on expert opinion. This study aimed to investigate the clinical features and outcomes of patients wit
Autor:
Brett M. Stevens, Mark D. Ewalt, Diana Abbott, Daniel A. Pollyea, Stephanie Chase, Jennifer Tobin, Molly Nakic, Chelsey Boggs, Jeffrey Schowinsky, Bradford Siegele, Steven R. Schuster, Jonathan A. Gutman, Keri Halsema, Enkhtsetseg Purev, Lindsey Lyle, Jeff Kaiser, Clayton A. Smith, Amanda Winters, Julie Rosser, Craig T. Jordan, Vishal Rana
Publikováno v:
Blood Advances. 3:2911-2919
Venetoclax is approved for older untreated acute myeloid leukemia (AML) patients. Venetoclax was available prior to approval off-label. We assessed our single-institution off-label experience with venetoclax/azacitidine, comparing outcomes with a cli
Publikováno v:
JPGN Reports. 3:e232
Publikováno v:
New England Journal of Medicine. 379:1072-1081
A Man with Epistaxis, Pain and Erythema of the Forearm, and Pancytopenia A 39-year-old man presented with epistaxis, pain and erythema of the arm, and pancytopenia, with neutropenia and monocytopen...
Autor:
Bradford Siegele, Yardena Samuels, J. Guy Lyons, J. Silvio Gutkind, Vachan Vadmal, Moraima Zaida, Zhiyong Wang, Lynn Vitale-Cross, Pablo Tamayo, Huwate Yeerna, Kun-Liang Guan, Alfredo A. Molinolo, Daniel Martin, Sok Ching Cheong, Juan Luis Callejas Valera, Ramiro Iglesias-Bartolome, Scott M. Lippman, Rick F. Thorne, Xiaodong Feng, Toshiro Moroishi, Maria Sol Degese
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature communications, vol 9, iss 1
Nature Communications
Nature communications, vol 9, iss 1
Nature Communications
Dysregulation of the Hippo signaling pathway and the consequent YAP1 activation is a frequent event in human malignancies, yet the underlying molecular mechanisms are still poorly understood. A pancancer analysis of core Hippo kinases and their candi
Autor:
Bradford Siegele, Taizo A. Nakano, Lauren R. S. Hill, Ann M. Kulungowski, Jessica Duis, Aparna Annam
Publikováno v:
Journal of Vascular Anomalies. 2:e011