Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Bradford S Schwartz"'
Autor:
Mats W. Johansson, Joseph Balnis, Laura K. Muehlbauer, Yury V. Bukhman, Matthew S. Stefely, Katherine A. Overmyer, Rachel Vancavage, Anupama Tiwari, Anish Raj Adhikari, Paul J. Feustel, Bradford S. Schwartz, Joshua J. Coon, Ron Stewart, Ariel Jaitovich, Deane F. Mosher
Publikováno v:
Physiological Reports, Vol 11, Iss 17, Pp n/a-n/a (2023)
Abstract Cartilage acidic protein‐1 (CRTAC1) is produced by several cell types, including Type 2 alveolar epithelial (T2AE) cells that are targeted by SARS‐CoV2. Plasma CRTAC1 is known based on proteomic surveys to be low in patients with severe
Externí odkaz:
https://doaj.org/article/c1f11d90a5054294aa369231a2511ab9
Autor:
John F. Swietlik, Anne E. Rose, Ece Meram, Bradford S. Schwartz, Jon S. Matsumura, Paul F. Laeseke
Publikováno v:
Journal of Vascular Surgery: Venous and Lymphatic Disorders.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cccf965867b88497a2da4706c0d422ef
https://doi.org/10.1016/j.jvsv.2023.04.005
https://doi.org/10.1016/j.jvsv.2023.04.005
Publikováno v:
Biochemical Journal
The mechanism of generation of factor VIIa, considered the initiating protease in the tissue factor-initiated extrinsic limb of blood coagulation, is obscure. Decreased levels of plasma VIIa in individuals with congenital factor IX deficiency suggest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::371c665d0579a1006ed41cb31f7b62c1
https://doi.org/10.1042/bcj20190595
https://doi.org/10.1042/bcj20190595
Publikováno v:
Journal of Thrombosis and Haemostasis. 19:1840-1841
We sadly report that John Suttie died on December 21, 2020, at the age of 86. John made vital contributions to the field of hemostasis and thrombosis. His early work was key to showing the action of vitamin K on the subset of coagulation factors know
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77411c7a1ccfc0397a092b03ee45735a
https://doi.org/10.1111/jth.15331
https://doi.org/10.1111/jth.15331
Autor:
Vanessa Linke, Edna A. Trujillo, Harold A. Singer, Dain R. Brademan, Deane F. Mosher, Laura K. Muehlbauer, Qiuwen Quan, Evgenia Shishkova, Matthew N. Bernstein, Bradford S Schwartz, Ian J. Miller, Ariel Jaitovich, Jesse G. Meyer, Trenton M. Peters-Clarke, Joshua J. Coon, Scott Swanson, Amit Chopra, Hau Chieng, Brett Paulson, Katherine A. Overmyer, Yunyun Zhu, Joseph Balnis, Anupama Tiwari, Yuchen He, Marc A. Judson, Ron Stewart, Lisa A. Drake, Alejandro P. Adam, Lia R. Serrano
Publikováno v:
Cell Systems
Journal of Translational Medicine
medRxiv
article-version (status) pre
article-version (number) 1
Journal of Translational Medicine
medRxiv
article-version (status) pre
article-version (number) 1
We performed RNA-Seq and high-resolution mass spectrometry on 128 blood samples from COVID-19 positive and negative patients with diverse disease severities and outcomes. Quantified transcripts, proteins, metabolites, and lipids were associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::590b3e958caa102293bf216fffc2d6d4
https://doi.org/10.1101/2020.07.17.20156513
https://doi.org/10.1101/2020.07.17.20156513
Autor:
R. Coleman Lindsley, Inga Hofmann, Sioban Keel, Colin C. Pritchard, Scott A. Coats, Tom Walsh, Rafael Márquez, Boglarka Gyurkocza, Mary Claire King, David A. Williams, Barbara Neistadt, Marshall S. Horwitz, Michael Y. Zhang, Melissa Forouhar, Christopher J. Mariani, Keith R. Loeb, Ryan Basom, Jeffrey J. Delrow, Ming K. Lee, Suleyman Gulsuner, Akiko Shimamura, Bradford S Schwartz, Janis L. Abkowitz, Marilyn Sanchez-Bonilla, Lucy A. Godley, Jane E. Churpek
Publikováno v:
Nature Genetics. 47:180-185
We report germline missense mutations in ETV6 segregating with the dominant transmission of thrombocytopenia and hematologic malignancy in three unrelated kindreds, defining a new hereditary syndrome featuring thrombocytopenia with susceptibility to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b813faef712e661ebfc35a76bb55e62
https://doi.org/10.1038/ng.3177
https://doi.org/10.1038/ng.3177
Publikováno v:
Journal of Biological Chemistry. 282:19502-19509
Maspin is a member of the serpin family with a reactive center loop that is incompatible with proteinase inhibition by the serpin conformational change mechanism. Despite this there are reports that maspin might regulate uPA-dependent processes in vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79846e4de4bb36dfd7c3cb20dd0f3ed5
https://doi.org/10.1074/jbc.m702445200
https://doi.org/10.1074/jbc.m702445200
Publikováno v:
Blood Coagulation & Fibrinolysis. 14:741-744
A 49-year-old male with alcoholic cirrhosis suffered several spontaneous, life-threatening, deep muscle bleeding episodes. Laboratory evaluation indicated excessive fibrinolysis with low plasminogen, low alpha2-antiplasmin, undetectable plasminogen a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f465489bbbd4ed6ee1dac7b5879f5b5
https://doi.org/10.1097/00001721-200312000-00008
https://doi.org/10.1097/00001721-200312000-00008
Publikováno v:
American Journal of Health-System Pharmacy. 57:1039-1045
The activity and sterility of reconstituted alteplase solution and the effectiveness of an alteplase dose-escalation protocol for the clearance of midline-catheter and central-venous-access device occlusions were studied. Reconstituted alteplase solu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::090971b1f3a29452081b79ec98ba67fd
https://doi.org/10.1093/ajhp/57.11.1039
https://doi.org/10.1093/ajhp/57.11.1039
Autor:
Francisco España, Bradford S. Schwartz
Publikováno v:
JOURNAL OF BIOLOGICAL CHEMISTRY
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Single-chain urokinase-type plasminogen activator (scu-PA) possesses enzymatic activity that increases by 2–3 orders of magnitude upon binding to its cellular cofactor, the u-PA receptor (u-PAR), hence activating an enzymatic cascade initially comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1497cc1bc405db0cb3fad05be875a163
https://doi.org/10.1074/jbc.274.21.15278
https://doi.org/10.1074/jbc.274.21.15278