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of 54
pro vyhledávání: '"Bradford R Hirsch"'
Autor:
Bradford R Hirsch, John M Burke, Manish Agrawal, Ralph J Hauke, Thomas E Hutson, Gury Doshi, Mark T Fleming, Nicholas J Vogelzang
Publikováno v:
Journal of Kidney Cancer and VHL, Vol 3, Iss 1, Pp 23-35 (2016)
The treatment of metastatic renal cell carcinoma (mRCC) has changed dramatically in the past decade. As the number of available agents, and related volume of research, has grown, it is increasingly complex to know how to optimally treat patients. The
Externí odkaz:
https://doaj.org/article/d0df7e06ded845189cfe1511e28aaeab
Autor:
Matthew Harker, S. Yousuf Zafar, Mark E. Fleury, Sheri Tibbs, Bradford R. Hirsch, Joseph M. Unger, Philip D'Almada, Karen Chiswell, George Tran, Kimberly D. Miller
Publikováno v:
JCO Clinical Cancer Informatics. :35-49
PURPOSE More than 20% of US clinical trials fail to accrue sufficiently. Our purpose was to provide a benchmark for better understanding clinical trial enrollment feasibility and to assess relative levels of competition for patients by cancer diagnos
Autor:
Karynsa Cetin, B. Diane Reams, Rohini K. Hernandez, Anne M. Butler, Amy P. Abernethy, Alexander Liede, Robert A. Overman, Jung In Kim, Bradford R. Hirsch, M. Alan Brookhart
Publikováno v:
Pharmacoepidemiology and Drug Safety. 27:229-238
Purpose To examine the dynamics of treatment with 2 bone-targeting agents (BTAs)-denosumab and zoledronic acid-among men with bone metastases from prostate cancer. Methods Using electronic health record data from oncology practices across the US, we
Autor:
Daniel J. George, Patricia Creel, Greg Samsa, Azah Borham, Bradford R. Hirsch, Nrupen A. Bhavsar, Michael R. Harrison, Ronit Simantov, Amy P. Abernethy, S. Wolf
Publikováno v:
Cancer Investigation. 35:333-344
The Metastatic Renal Cell Cancer Registry, a large, nationally representative, prospective registry of patients with metastatic renal cell carcinoma (mRCC), aims to understand real-world treatment patterns and outcomes of patients with mRCC in routin
Autor:
Julie K. Silver, Celena Scheede-Bergdahl, Liane S. Feldman, Ann Gamsa, Sean Gilman, Andrea B. McKee, Chelsia Gillis, Nicole L. Stout, Francesco Carli, Bradford R. Hirsch
Publikováno v:
Physical Medicine and Rehabilitation Clinics of North America. 28:49-64
This review by a 10-member panel of experts in surgical prehabilitation addresses processes that may improve oncologic care. Surgical prehabilitation is the process on the continuum of care that occurs between the time of cancer diagnosis and the beg
Autor:
Amy P. Abernethy, Bradford R. Hirsch
Publikováno v:
Personalized medicine. 9(8)
Personalized medicine is the future of clinical care. Many interpret this to mean that advances in genomic medicine will revolutionize care. However, the reality is much more complex, relying on a combination of health technology, patient engagement,
Autor:
Mark S. Walker, Amy P. Abernethy, Daniel J. George, Aaron P. Mitchell, Michael R. Harrison, Bradford R. Hirsch
Publikováno v:
Journal of Oncology Practice. 11:491-497
Although narrow eligibility criteria improve the internal validity of clinical trials, they may result in differences between study populations and real-world patients, threatening generalizability. Therefore, we evaluated whether patients treated fo
Autor:
Bradford R. Hirsch, Gary H. Lyman
Publikováno v:
Blood Reviews. 28:263-268
As the cost of healthcare continues to rise and patents on biologics near expiration, biosimilars are gaining visibility as a mechanism for cost reduction. Yet, the introduction of biosimilars into the U.S. market will be complex, due to the related
Autor:
Connie Chen, Beata Korytowsky, Edward J. Stepanski, Michael R. Harrison, Bradford R. Hirsch, Daniel J. George, Mark S. Walker, Amy P. Abernethy
Publikováno v:
Journal of Oncology Practice. 10:e63-e72
As new therapeutics for metastatic renal cell carcinoma (mRCC) are quickly introduced to market, comparative randomized trial evidence guiding treatment decisions is lacking, especially in the second treatment exposure and beyond. As a demonstration
Autor:
S. Yousuf Zafar, Bradford R. Hirsch
Publikováno v:
Seminars in Radiation Oncology. 24:49-53
Comparative effectiveness research (CER) is critically needed in medical oncology to improve the care being delivered to oncology patients. As medical oncologists are forced to rely on insufficient data as a part of daily treatment decision making, a