Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Braden Sweeting"'
Autor:
Felix S. Meier‐Stephenson, Vanessa C. Meier‐Stephenson, Michael D. Carter, Autumn R. Meek, Yanfei Wang, Luzhe Pan, Qiangwei Chen, Sheila Jacobo, Fan Wu, Erhu Lu, Gordon A. Simms, Laural Fisher, Alaina J. McGrath, Virgil Fermo, Christopher J. Barden, Harman D.S. Clair, Todd N. Galloway, Arun Yadav, Valérie Campágna‐Slater, Mark Hadden, Mark Reed, Marcia Taylor, Brendan Kelly, Elena Diez‐Cecilia, Igri Kolaj, Clarissa Santos, Imindu Liyanage, Braden Sweeting, Paul Stafford, Robert Boudreau, G. Andrew Reid, Ryan S. Noyce, Leanne Stevens, Agnieszka Staniszewski, Hong Zhang, Mamidanna R. V. S. Murty, Pascale Lemaire, Solenne Chardonnet, Christopher D. Richardson, Valérie Gabelica, Edwin DePauw, Richard Brown, Sultan Darvesh, Ottavio Arancio, Donald F. Weaver
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 8, Iss 1, Pp n/a-n/a (2022)
Abstract Introduction Alzheimer's disease (AD) is characterized by neurotoxic immuno‐inflammation concomitant with cytotoxic oligomerization of amyloid beta (Aβ) and tau, culminating in concurrent, interdependent immunopathic and proteopathic path
Externí odkaz:
https://doaj.org/article/1e2d8b504a1f482e94ad2f6036b37c9c
N-terminal helix-cap in α-helix 2 modulates β-state misfolding in rabbit and hamster prion proteins.
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63047 (2013)
Susceptibility of a particular species to prion disease is affected by small differences in the sequence of PrP and correlates with the propensity of its PrP to assume the β-state. A helix-cap motif in the β2-α2-loop of native α-helical rabbit Pr
Externí odkaz:
https://doaj.org/article/f2666b05672e4a3d8eb7289d6c7c9200
Autor:
Brendan J. Kelly, Elena Diez-Cecilia, Luzhe Pan, Braden Sweeting, Laura Villar, Alexander Kreft, Mayuri Gupta, Shea L. Johnson, Donald F. Weaver
Publikováno v:
Canadian Journal of Chemistry. 100:660-675
The design of potent indoleamine 2,3-dioxygenase 1 (IDO1) enzyme inhibitors targeting immunopathic neuroinflammation has emerged as an area of interest for the treatment of Alzheimer's disease (AD); additionally, recent findings on the clinical benef
Autor:
Léo Sauvaget, Raja Ghosh, Melih Tamer, Umatheny Umatheva, Nerissa Dela Rosa, Braden Sweeting, John Riley
Publikováno v:
Biochemical Engineering Journal. 164:107760
Pertussis, or whooping cough, is a contagious bacterial disease, caused by Bordetella pertussis. It is airborne and causes coughing fits, difficulty in breathing, and even death. Whooping cough is life-threatening but could be prevented by proper imm
Autor:
Scott C Banfield, Shaolong Zhu, Kunal Keskar, Derek J. Wilson, Erhu Lu, Arun Yadav, Marcia Taylor, Seung-Pil Yang, Donald F. Weaver, Christopher J. Barden, Yanfei Wang, Bin Deng, Braden Sweeting, Fan Wu, Luhze Pan, Mark Reed, Kurt R. Stover
Publikováno v:
Alzheimer's & Dementia. 13
Autor:
Scott C Banfield, Anandi Bhattacharya, Erhu Lu, Christopher J. Barden, Fan Wu, Donald F. Weaver, Marcy Taylor, Braden Sweeting, Arun Yadav, Yanfei Wang, Seung-Pil Yang, Mark Reed
Publikováno v:
Alzheimer's & Dementia. 12
Autor:
Braden Sweeting, Anandi Bhattacharya, Fan Wu, Christopher J. Barden, Arun Yadav, Erhu Lu, Seung-Pil Yang, Marcy Taylor, Donald F. Weaver, Mark Reed, Yanfei Wang
Publikováno v:
Alzheimer's & Dementia. 12
Autor:
Shaolong Zhu, Marcia Taylor, Heinz-Bernhard Kraatz, Derek J. Wilson, Bin Deng, Mark Reed, Braden Sweeting
Publikováno v:
Alzheimer's & Dementia. 12
Autor:
Christopher J. Barden, Mark Reed, Scott C Banfield, Arun Yadav, Braden Sweeting, Erhu Lu, Donald F. Weaver, Marcia Taylor, Seung-Pil Yang, Fan Wu, Yanfei Wang
Publikováno v:
Alzheimer's & Dementia. 11
Autor:
Marcia Taylor, Donald F. Weaver, Scott C Banfield, Seung-Pil Yang, Erhu Lu, Mark Reed, Braden Sweeting, Yanfei Wang, Christopher J. Barden, Pamela Gallant, Arun Yadav
Publikováno v:
Alzheimer's & Dementia. 10
Background and Hypothesis: Both beta amyloid and tau produce neurotoxic protein misfolding co-conspirators most often implicated in the molecular causation of AD. Moreover, since the clinical presentation of AD is heterogeneous (e.g. extrapyramidal s