Anti-tumor Activity of miniPEG-γ-Modified PNAs to Inhibit MicroRNA-210 for Cancer Therapy.

Autor: Gupta A; Department of Therapeutic Radiology, Yale University, New Haven, CT 06510, USA., Quijano E; Department of Biomedical Engineering, Yale University, New Haven, CT 06520, USA., Liu Y; Department of Therapeutic Radiology, Yale University, New Haven, CT 06510, USA., Bahal R; Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269, USA., Scanlon SE; Department of Therapeutic Radiology, Yale University, New Haven, CT 06510, USA., Song E; Department of Biomedical Engineering, Yale University, New Haven, CT 06520, USA., Hsieh WC; Department of Chemistry and Center for Nucleic Acids Science and Technology (CNAST), Carnegie Mellon University, Pittsburgh, PA 15213, USA., Braddock DE; Department of Pathology, Yale University, New Haven, CT 06510, USA., Ly DH; Department of Chemistry and Center for Nucleic Acids Science and Technology (CNAST), Carnegie Mellon University, Pittsburgh, PA 15213, USA., Saltzman WM; Department of Biomedical Engineering, Yale University, New Haven, CT 06520, USA., Glazer PM; Department of Therapeutic Radiology, Yale University, New Haven, CT 06510, USA; Department of Genetics, Yale University, New Haven, CT 06510, USA. Electronic address: peter.glazer@yale.edu.

Publikováno v: Molecular therapy. Nucleic acids [Mol Ther Nucleic Acids] 2017 Dec 15; Vol. 9, pp. 111-119. Date of Electronic Publication: 2017 Sep 12.