Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Bradbeer, Jeremy"'
Autor:
Miller, William H., Bondinell, William E., Cousins, Russell D., Erhard, Karl F., Jakas, Dalia R., Keenan, Richard M., Ku, Thomas W., Newlander, Kenneth A., Ross, Stephen T., Haltiwanger, R.Curtis, Bradbeer, Jeremy, Drake, Fred H., Gowen, Maxine, Hoffman, Sandra J., Hwang, Shing-Mei, James, Ian E., Lark, Michael W., Lechowska, Beata, Rieman, David J., Stroup, George B., Vasko-Moser, Janice A., Zembryki, Denise L., Azzarano, Leonard M., Adams, Paula C., Salyers, Kevin L., Smith, Brian R., Ward, Keith W., Johanson, Kyung O., Huffaman, William F.
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 1999 9(13):1807-1812
We investigated the determinants of bone formation at individual remodeling sites (BMUs) in cancellous bone from 8 osteologically normal, sex hormone-replete women with endometriosis. All were tetracycline double- labeled (2, 12, 2, and 4 day regime)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::892a04d1d8a2605daf16884772424049
https://ora.ox.ac.uk/objects/uuid:9d1ec6e1-1ea3-4ce9-85dd-21197b3ff5b4
https://ora.ox.ac.uk/objects/uuid:9d1ec6e1-1ea3-4ce9-85dd-21197b3ff5b4
Autor:
David J. Rieman, William F. Huffaman, Kevin L. Salyers, Richard M. Keenan, Michael W. Lark, Janice A. Vasko-Moser, Thomas W. Ku, Maxine Gowen, Leonard M. Azzarano, Karl F. Erhard, Stephen T. Ross, Denise Zembryki, Bradbeer Jeremy N, Bondinell William E, Shing-Mei Hwang, William H. Miller, Kenneth A. Newlander, George B. Stroup, Beata Lechowska, Fred H. Drake, Keith W. Ward, Kyung O. Johanson, Brian R. Smith, Paula C. Adams, Ian E. James, R. Curtis Haltiwanger, Russell D. Cousins, Dalia R. Jakas, Sandra J. Hoffman
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 9:1807-1812
A new series of potent nonpeptide vitronectin receptor antagonists, based on a novel carbocyclic Gly-Asp mimetic, has been discovered. A representative of this series, SB 265123 (4), has 100% oral bioavailability in rats, and is orally active in vivo
Autor:
Sandra J. Hoffman, Maxine Gowen, Daniel P. Nadeau, Sabine Rehm, Mark Nuttall, Bradbeer Jeremy N, George B. Stroup, Hugh Zhao
Publikováno v:
Endocrinology. 139:5224-5234
Idoxifene, a novel selective estrogen receptor modulator, was tested for its effects on bone loss, serum cholesterol, and uterine wet weight and histology in the ovariectomized (Ovx) rat. Idoxifene (0.5 mg/kg x day) completely prevented loss of both
Autor:
Thomas Joseph Carr, Mary J. Bossard, Alison M. Badger, Thaddeus A. Tomaszek, Fred H. Drake, Mark Alan Levy, Lawrence Szewczuk, Scott K. Thompson, Ian E. James, Bartholomew J. Votta, Daniel F. Veber, Maxine Gowen, Janice R. Connor, R.A. Dodds, Bradbeer Jeremy N
Publikováno v:
Journal of Bone and Mineral Research. 12:1396-1406
We have shown previously that cathepsin K, a recently identified member of the papain superfamily of cysteine proteases, is expressed selectively in osteoclasts and is the predominant cysteine protease in these cells. Based upon its abundant cell typ
Autor:
Mara Riminucci, Chiara Gentili, Fiorella Descalzi, Paolo Bianco, Bradbeer Jeremy N, Ranieri Cancedda, Alessandro Corsi
Bone formation throughout skeletal growth and remodeling always entails deposition of new bone onto a pre-existing mineralized surface. In contrast, the initial deposition of bone in development requires the formation, ex novo, of the first mineraliz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32a6b8f713bb6f7078f0ef4834d0a0d9
http://hdl.handle.net/11567/186303
http://hdl.handle.net/11567/186303
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 9(11)
Monoclonal antibodies (MAb) may provide valuable tools for studying osteoblast differentiation. We therefore raised a panel of MAb reactive with cells of this phenotype using 1,25(OH)2D3-treated human trabecular osteoblast-like cells (HOBS) as the im
Publikováno v:
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 42(5)
We present evidence for a previously unrecognized differential staining effect of Giemsa solution in fluorescence microscopy. The effect consists of selective fluorescent staining of mineralized bone (and elastic fibers) in tissue sections and, like
Autor:
Paolo Bianco, Ermanno Bonucci, Sandro Mazzaferro, Giorgio Coen, Bradbeer Jeremy N, Paola Ballanti
Alkaline phosphatase (ALP) activity was used as a novel histomorphometric index of osteoblastic surfaces involved in mineralization. The enzyme cytochemical reaction was done on sections of low temperature processed, glycol methacrylate (GMA) embedde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6dbdb4cadacf055311183e0cb669e98
http://hdl.handle.net/11573/418570
http://hdl.handle.net/11573/418570