Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Brad R Rosenberg"'
Publikováno v:
PLoS Pathogens, Vol 18, Iss 4, p e1010464 (2022)
Interferons establish an antiviral state through the induction of hundreds of interferon-stimulated genes (ISGs). The mechanisms and viral specificities for most ISGs remain incompletely understood. To enable high-throughput interrogation of ISG anti
Externí odkaz:
https://doaj.org/article/1e935b4c437d4d03ac0378f26c0767c1
Autor:
Joy E Tomlinson, Raphael Wolfisberg, Ulrik Fahnøe, Himanshu Sharma, Randall W Renshaw, Louise Nielsen, Eiko Nishiuchi, Christina Holm, Edward Dubovi, Brad R Rosenberg, Bud C Tennant, Jens Bukh, Amit Kapoor, Thomas J Divers, Charles M Rice, Gerlinde R Van de Walle, Troels K H Scheel
Publikováno v:
PLoS Pathogens, Vol 16, Iss 7, p e1008677 (2020)
Pegiviruses frequently cause persistent infection (as defined by >6 months), but unlike most other Flaviviridae members, no apparent clinical disease. Human pegivirus (HPgV, previously GBV-C) is detectable in 1-4% of healthy individuals and another 5
Externí odkaz:
https://doaj.org/article/86b673d6cd5a45f290ac6aa03731e272
Autor:
Leon Louis Seifert, Clara Si, Debjani Saha, Mohammad Sadic, Maren de Vries, Sarah Ballentine, Aaron Briley, Guojun Wang, Ana M Valero-Jimenez, Adil Mohamed, Uwe Schaefer, Hong M Moulton, Adolfo García-Sastre, Shashank Tripathi, Brad R Rosenberg, Meike Dittmann
Publikováno v:
PLoS Pathogens, Vol 15, Iss 11, p e1007634 (2019)
Induction of vast transcriptional programs is a central event of innate host responses to viral infections. Here we report a transcriptional program with potent antiviral activity, driven by E74-like ETS transcription factor 1 (ELF1). Using microscop
Externí odkaz:
https://doaj.org/article/b03626d26f984d858fa7bd392b467346
Autor:
Brad R Rosenberg, Marion Depla, Catherine A Freije, Denis Gaucher, Sabrina Mazouz, Maude Boisvert, Nathalie Bédard, Julie Bruneau, Charles M Rice, Naglaa H Shoukry
Publikováno v:
PLoS Pathogens, Vol 14, Iss 9, p e1007290 (2018)
Most individuals exposed to hepatitis C virus (HCV) become persistently infected while a minority spontaneously eliminate the virus. Although early immune events influence infection outcome, the cellular composition, molecular effectors, and timefram
Externí odkaz:
https://doaj.org/article/b465ecfd4e654bf39641f37a32ae4bfe
Autor:
Louise Malle, Roosheel S. Patel, Marta Martin-Fernandez, O Jay Stewart, Quentin Philippot, Sofija Buta, Ashley Richardson, Vanessa Barcessat, Justin Taft, Paul Bastard, Julie Samuels, Clotilde Mircher, Anne-Sophie Rebillat, Louise Maillebouis, Marie Vilaire-Meunier, Kevin Tuballes, Brad R. Rosenberg, Rebecca Trachtman, Jean-Laurent Casanova, Luigi D. Notarangelo, Sacha Gnjatic, Douglas Bush, Dusan Bogunovic
Publikováno v:
Nature. 615:305-314
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78f5c8f8493c5ac5c89988ecf1f57589
https://doi.org/10.1038/s41586-023-05736-y
https://doi.org/10.1038/s41586-023-05736-y
Autor:
Rachel A. Prescott, Alec P. Pankow, Maren de Vries, Keaton Crosse, Roosheel S. Patel, Mark Alu, Cynthia Loomis, Victor Torres, Sergei Koralov, Ellie Ivanova, Meike Dittmann, Brad R. Rosenberg
The airway epithelium is composed of diverse cell types with specialized functions that mediate homeostasis and protect against respiratory pathogens. Human airway epithelial cultures at air-liquid interface (HAE) are a physiologically relevantin vit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05d245dccf91636d85ecedbb1d7fadc6
https://doi.org/10.1101/2023.02.27.530299
https://doi.org/10.1101/2023.02.27.530299
Publikováno v:
Methods in Molecular Biology ISBN: 9781071630839
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed5ed77fd39d30f3790845ee218262eb
https://doi.org/10.1007/978-1-0716-3084-6_20
https://doi.org/10.1007/978-1-0716-3084-6_20
Autor:
Thomas Kehrer, Anastasija Cupic, Chengjin Ye, Soner Yildiz, Mehdi Bouhhadou, Nicholas A Crossland, Erika Barrall, Phillip Cohen, Anna Tseng, Tolga Çağatay, Raveen Rathnasinghe, Daniel Flores, Sonia Jangra, Fahmida Alam, Nacho Mena, Sadaf Aslam, Anjali Saqi, Arturo Marin, Magdalena Rutkowska, Manisha R. Ummadi, Giuseppe Pisanelli, R. Blake Richardson, Ethan C. Veit, Jacqueline M. Fabius, Margaret Soucheray, Benjamin J. Polacco, Matthew J. Evans, Danielle L. Swaney, Ana S. Gonzalez-Reiche, Emilia M. Sordillo, Harm van Bakel, Viviana Simon, Lorena Zuliani-Alvarez, Beatriz M. A. Fontoura, Brad R. Rosenberg, Nevan J. Krogan, Luis Martinez-Sobrido, Adolfo García-Sastre, Lisa Miorin
Publikováno v:
bioRxiv
We and others have previously shown that the SARS-CoV-2 accessory protein ORF6 is a powerful antagonist of the interferon (IFN) signaling pathway by directly interacting with Nup98-Rae1 at the nuclear pore complex (NPC) and disrupting bidirectional n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4866000179c2b1068fefa7cc2e63f323
https://doi.org/10.1101/2022.10.18.512708
https://doi.org/10.1101/2022.10.18.512708
Autor:
Joshua A Acklin, Aum R Patel, Shu Horiuchi, Arianna S Moss, Andrew P Kurland, Patricia Thibault, Emma J Degrace, Satoshi Ikegame, Jillian Carmichael, Naoko Imai, Hideki Ueno, Benjamin Tweel, Jeffrey R Johnson, Brad R Rosenberg, Benhur Lee, Jean K Lim
Lymph nodes are the primary site of replication for measles virus (MeV). Here, we modeled MeV infection in human tonsil explants, utilizing a clinical strain of MeV that expresses GFP. We show that MeV replicates efficiently in this tissue as measure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b0533636f96bd4118d3ef2abb311dd4
https://doi.org/10.1101/2022.09.12.507535
https://doi.org/10.1101/2022.09.12.507535
Publikováno v:
Current protocols. 2(6)
A diverse collection of viral pathogens target airway epithelial cells for infection, with effects ranging from mild upper respiratory tract symptoms to death of the infected individual. Among these pathogens are recently discovered and/or emergent v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b183674cf9f43103bac80579fdf3dad1
https://pubmed.ncbi.nlm.nih.gov/35671174
https://pubmed.ncbi.nlm.nih.gov/35671174