Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Brad L. Jakubison"'
Autor:
Brad L. Jakubison, Tanmoy Sarkar, Kristbjorn O. Gudmundsson, Shweta Singh, Lei Sun, Holly M. Morris, Kimberly D. Klarmann, Jonathan R. Keller
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 13 (2022)
Defining mechanism(s) that maintain tissue stem quiescence is important for improving tissue regeneration, cell therapies, aging, and cancer. We report here that genetic ablation of Id2 in adult hematopoietic stem cells (HSCs) promotes increased HSC
Externí odkaz:
https://doaj.org/article/c11c062cb0a34b3e9bd58c5127f5532d
Autor:
Brad L. Jakubison, Patrick G. Schweickert, Sarah E. Moser, Yi Yang, Hongyu Gao, Kathleen Scully, Pamela Itkin‐Ansari, Yunlong Liu, Stephen F. Konieczny
Publikováno v:
Molecular Oncology, Vol 12, Iss 7, Pp 1104-1124 (2018)
Pancreatic acinar cells synthesize, package, and secrete digestive enzymes into the duodenum to aid in nutrient absorption and meet metabolic demands. When exposed to cellular stresses and insults, acinar cells undergo a dedifferentiation process ter
Externí odkaz:
https://doaj.org/article/df1b2588e5bb4fdfa3d2f06303c80673
Autor:
Brad L. Jakubison, Tanmoy Sarkar, Kristbjorn O. Gudmundsson, Shweta Singh, Lei Sun, Holly M. Morris, Kimberly D. Klarmann, Jonathan R. Keller
Publikováno v:
The Journal of clinical investigation. 132(13)
Defining mechanism(s) that maintain tissue stem quiescence is important for improving tissue regeneration, cell therapies, aging, and cancer. We report here that genetic ablation of Id2 in adult hematopoietic stem cells (HSCs) promotes increased HSC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b6bf8c360200fda77f6983b41ab0193
https://pubmed.ncbi.nlm.nih.gov/35775482
https://pubmed.ncbi.nlm.nih.gov/35775482
Autor:
Reyhaneh Lahmy, Stephen F. Konieczny, Yifan Wu, Keith P. Gates, Pamela Itkin-Ansari, Claudio Staub, Chelsea Riha, Brad L. Jakubison, Challeng Yang, Jaco Van Niekerk, Sang Wun Kim, Duc Si Dong
Publikováno v:
Pancreas
Supplemental digital content is available in the text.
Objectives Pancreatic ductal adenocarcinoma (PDA) initiates from quiescent acinar cells that attain a Kras mutation, lose signaling from basic helix-loop-helix (bHLH) transcription factors,
Objectives Pancreatic ductal adenocarcinoma (PDA) initiates from quiescent acinar cells that attain a Kras mutation, lose signaling from basic helix-loop-helix (bHLH) transcription factors,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45d6e3a36eb216821096df7522fe8d20
https://pubmed.ncbi.nlm.nih.gov/26061556
https://pubmed.ncbi.nlm.nih.gov/26061556
Autor:
Challeng Yang, Reyhaneh Lamy, Pamela Itkin-Ansari, Brad L. Jakubison, Sangwun Kim, Stephen F. Konieczny, Chelsea Riha
Publikováno v:
Cancer Research. 75:A13-A13
Pancreatic ductal adenocarcinoma (PDA) initiates from quiescent acinar cells that attain a Kras mutation, undergo acinar-ductal metaplasia and rapidly acquire increased growth potential. During this process several transcription factors from the basi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9731098067a3d571bcac70499f432dd
https://doi.org/10.1158/1538-7445.panca2014-a13
https://doi.org/10.1158/1538-7445.panca2014-a13