Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Brad Henkle"'
Autor:
Thomas M. Dillon, Yaoqing Diana Liu, Matthew H. Plant, Songpon Deechongkit, Yu Li, Chris Vezina, Brad Henkle, Brian Varnum, Gregory C. Flynn, Douglas Rehder, Pavel V. Bondarenko, Margaret Speed Ricci, Jette Wypych, Alain Balland
Publikováno v:
Journal of Biological Chemistry. 283:16206-16215
In the accompanying report ( Wypych, J., Li, M., Guo, A., Zhang, Z., Martinez, T., Allen, M. J., Fodor, S., Kelner, D. N., Flynn, G. C., Liu, Y. D., Bondarenko, P. V., Ricci, M. S., Dillon, T. M., and Balland, A. (2008) J. Biol. Chem. 283, 16194-1620
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c5eb3823a1e2bff7b19d433797507bb
https://doi.org/10.1074/jbc.m709988200
https://doi.org/10.1074/jbc.m709988200
Autor:
Kurt Morgenstern, Matthew W. Martin, Faye Hsieh, Stuart C. Chaffee, Susan A. Tomlinson, Susan M. Turci, Joseph J. Nunes, Lilly Chai, Paul E. Rose, Josie H. Lee, Antonio J. Oliveira-dos-Santos, Erin F. DiMauro, Vinod F. Patel, David Powers, Yan Gu, Xin Huang, Jean Bemis, Andrew A. Welcher, David C. Mcgowan, Huilin Zhao, Joseph L. Kim, Xiaotian Zhu, Holly L. Deak, Li Zhu, Yanyan Tudor, Ted Faust, Linda F. Epstein, Christina Boucher, Anu Gore, Deanna Mohn, Stephen Schneider, John Newcomb, Daniela Metz, Brad Henkle, Paul Gallant
Publikováno v:
Journal of Medicinal Chemistry. 51:1681-1694
The lymphocyte-specific kinase (Lck), a member of the Src family of cytoplasmic tyrosine kinases, is expressed in T cells and natural killer (NK) cells. Genetic evidence, including knockout mice and human mutations, demonstrates that Lck kinase activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cea8884d0e69b4d85c6e3a74c4f98b0f
https://doi.org/10.1021/jm7010996
https://doi.org/10.1021/jm7010996
Autor:
Joseph L. Kim, Xiaotian Zhu, William H. Buckner, Josie H. Lee, Vinod F. Patel, Lilly Chai, Antonio J. Oliveira-dos-Santos, Ryan White, Holly L. Deak, Brian L. Hodous, Joseph J. Nunes, John L. Buchanan, Paul E. Rose, Huilin Zhao, Andrew A. Welcher, Stephanie D. Geuns-Meyer, Linda F. Epstein, David Powers, Yan Gu, Stephen Schneider, Kurt Morgenstern, Anu Gore, Victor J. Cee, Yanyan Tudor, Ted Faust, Susan A. Tomlinson, Xin Huang, Erin F. DiMauro, Jean Bemis, Susan M. Turci, John Newcomb, David C. Mcgowan, Faye Hsieh, Brad Henkle, Deanna Mohn, Christina Boucher, Li Zhu, Matthew W. Martin, Paul Gallant, Craig E. Masse, Daniela Metz
Publikováno v:
Journal of Medicinal Chemistry. 49:5671-5686
The lymphocyte-specific kinase (Lck) is a cytoplasmic tyrosine kinase of the Src family expressed in T cells and natural killer (NK) cells. Genetic evidence in both mice and humans demonstrates that Lck kinase activity is critical for signaling media
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbddeb8cdb894dbfd55fa63c5040ddcf
https://doi.org/10.1021/jm0605482
https://doi.org/10.1021/jm0605482
Autor:
Yang Xu, Mike Fiorino, Elizabeth Tominey, Min Wong, Lisa Sherman, Victor J. Cee, Roland Burli, Brad Henkle, Han Xu, Jerry Siu, Keith Kelley, Matt Adlam, Michele McElvain
Publikováno v:
Journal of biomolecular screening. 18(9)
Surrogate readouts of G-protein-coupled receptor signaling pathways using highly engineered systems are often employed in the drug discovery process. However, accumulating data have demonstrated the importance of selecting relevant biological activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::603ba7984cf81c79f7957f8df7df0d1a
https://pubmed.ncbi.nlm.nih.gov/23686102
https://pubmed.ncbi.nlm.nih.gov/23686102
Autor:
Erin F. DiMauro, John Newcomb, Joseph J. Nunes, Jean E. Bemis, Christina Boucher, Lilly Chai, Stuart C. Chaffee, Holly L. Deak, Linda F. Epstein, Ted Faust, Paul Gallant, Anu Gore, Yan Gu, Brad Henkle, Faye Hsieh, Xin Huang, Joseph L. Kim, Josie H. Lee, Matthew W. Martin, David C. McGowan
Publikováno v:
Journal of Medicinal Chemistry; Feb2008, Vol. 51 Issue 6, p1681-1694, 14p