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of 2
pro vyhledávání: '"Brad Greatrix"'
Autor:
Karin Wertz, Christopher Lankin, Samir Acharya, Georges Riss, Brad Greatrix, Nicole Seifert, Petra Buchwald-Hunziker, Regina Goralczyk, Ulrich Hoeller, Emmanuelle Kuntz, Willi Hunziker
Publikováno v:
Archives of Biochemistry and Biophysics. 455:48-60
High dose beta-carotene supplementation of smokers was associated with increased lung cancer risk in two intervention trials. It was proposed that generation of apocarotenals in smoke-exposed lungs impaired retinoic acid (RA) signaling, leading to sq
Autor:
Regina Goralczyk, Karin Wertz, Heinrich Bachmann, Petra Buchwald Hunziker, Claude-Pierre Aebischer, Brad Greatrix, Barbara Lenz, Georges Riss
Publikováno v:
Nutrition and Cancer. 54:252-262
Dietary modulation of cancer & cancer biomarkers; Dietary modulation of carcinogenesis-related pathways. Dietary item or component studied: beta-carotene Outcome studied: lung adenoma; gene regulation of the putative tumor suppressor RARbeta in mouse