Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Brad F. Droy"'
Publikováno v:
Canadian Journal of Fisheries and Aquatic Sciences. 49:1070-1077
Sulfadimethoxine (SDM), a sulfonamide antibacterial drug, was examined in regards to bioavailability, pharmacokinetics, distribution, plasma protein binding, mass balance, and metabolism in the rainbow trout (Oncorhynchus mykiss). Analysis of SDM pha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6f711d245e26400f973ae25451995c0
https://doi.org/10.1139/f92-118
https://doi.org/10.1139/f92-118
Publikováno v:
Xenobiotica. 20:147-157
1. Uptake, bioavailability, tissue disposition, and elimination of 14C were examined in rainbow trout following intravascular and per os dosing of 14C-ormetoprim (8 mg/kg). 2. Plasma clearance was rapid following a single i.v. dose (t1/2 alpha = 0.54
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd7994be69b62176047a57f25169d40b
https://doi.org/10.3109/00498259009047150
https://doi.org/10.3109/00498259009047150
Autor:
Brad F. Droy, David E. Hinton
Publikováno v:
Marine Environmental Research. 24:259-264
Rainbow trout liver is tubular without apparent lobules. Hepatotoxins are often defined by the portion of the hepatic lobule affected. One of these, carbon tetrachloride, has been studied in trout and has produced no consistent pattern of toxicity si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a89a07063f6be84e5dabeb61c927a287
https://doi.org/10.1016/0141-1136(88)90317-0
https://doi.org/10.1016/0141-1136(88)90317-0
Publikováno v:
Aquatic Toxicology. 13:155-166
Monoclonal antibodies (MAB) directed against 5-bromo, 2′deoxyuridine (BrdU) were used to detect cells in which carbon tetrachloride-induced DNA synthesis had occurred in livers of rainbow trout ( Salmo gairdneri ) and of rats. Trout exposed to CCl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09b9e0db84defca01ce80191480127f6
https://doi.org/10.1016/0166-445x(88)90040-9
https://doi.org/10.1016/0166-445x(88)90040-9
Publikováno v:
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology. 94(1)
1. Half lives of distribution and elimination phases of 14C-sulfadimethoxine following i.v. dosing of sulfadimethoxine/ormetoprim (SDM/OMP, 42/8 mg/kg) were 0.4 and 16.1 hr respectively. The apparent volume of distribution was 503.9 ml/kg. 2. In vitr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fda7b77e6365041d5ff10b4b8d17869
https://pubmed.ncbi.nlm.nih.gov/2576741
https://pubmed.ncbi.nlm.nih.gov/2576741
Publikováno v:
Toxicology and applied pharmacology. 98(2)
Hepatotoxicity of allyl formate (AF) was studied in trout, to characterize the response of the teleost liver to a mammalian periportal hepatotoxicant. A dose-dependent decrease in liver nonprotein sulfhydryl (NPSH) concentration was observed at 3, 6,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73f52e86357fbd7da9c9d484861f10c9
https://pubmed.ncbi.nlm.nih.gov/2711394
https://pubmed.ncbi.nlm.nih.gov/2711394