Zobrazeno 1 - 10
of 190
pro vyhledávání: '"Brad E Zacharia"'
Autor:
Ricardo J Komotar, Brad E Zacharia, Robert A McGovern, Michael B Sisti, Jeffrey N Bruce, Anthony L D′Ambrosio
Publikováno v:
Journal of Craniovertebral Junction and Spine, Vol 1, Iss 2, Pp 86-99 (2010)
Foramen magnum (FM) lesions represent some of the most complex cases for the modern neurosurgeon because of their location near vital brainstem structures, the vertebral arteries, and lower cranial nerves. In particular, anterior or anterolaterally l
Externí odkaz:
https://doaj.org/article/912e2a28805847acbcd8915e4c565e97
Autor:
Joseph A. Miccio, Zizhong Tian, Sean S. Mahase, Christine Lin, Serah Choi, Brad E. Zacharia, Jason P. Sheehan, Paul D. Brown, Daniel M. Trifiletti, Joshua D. Palmer, Ming Wang, Nicholas G. Zaorsky
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-12 (2024)
Abstract Background Brain metastases (BM) affect clinical management and prognosis but limited resources exist to estimate BM risk in newly diagnosed cancer patients. Additionally, guidelines for brain MRI screening are limited. We aimed to develop a
Externí odkaz:
https://doaj.org/article/f578ab728bf348cf95904caea5fe65be
Autor:
Ganesh Shenoy, Becky Slagle-Webb, Chachrit Khunsriraksakul, Bhavyata Pandya Shesh, Jingqin Luo, Vladimir Khristov, Nataliya Smith, Alireza Mansouri, Brad E. Zacharia, Sheldon Holder, Justin D. Lathia, Jill S. Barnholtz-Sloan, James R. Connor
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The association between anemia and outcomes in glioblastoma patients is unclear. We analyzed data from 1346 histologically confirmed adult glioblastoma patients in the TriNetX Research Network. Median hemoglobin and hematocrit levels were qu
Externí odkaz:
https://doaj.org/article/a9d3c20eb2d84732ac22809af3797fa9
Autor:
Andrew F Ducruet, Brad E Zacharia, Sergey A Sosunov, Paul R Gigante, Mason L Yeh, Justin W Gorski, Marc L Otten, Richard Y Hwang, Peter A DeRosa, Zachary L Hickman, Paulina Sergot, E Sander Connolly
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38664 (2012)
The restoration of blood-flow following cerebral ischemia incites a series of deleterious cascades that exacerbate neuronal injury. Pharmacologic inhibition of the C3a-receptor ameliorates cerebral injury by attenuating post-ischemic inflammation. Re
Externí odkaz:
https://doaj.org/article/86b13f22d9e74f47a810f87d721e7612
Autor:
Sebastian F. Koga, Wesley B. Hodges, Hayk Adamyan, Tim Hayes, Peter E. Fecci, Vadim Tsvankin, Gustavo Pradilla, Kimberly B. Hoang, Ian Y. Lee, Eric W. Sankey, Patrick J. Codd, David Huie, Brad E. Zacharia, Ragini Verma, Vatche G. Baboyan
Publikováno v:
Frontiers in Neurology, Vol 14 (2024)
BackgroundPeritumoral edema alters diffusion anisotropy, resulting in false negatives in tractography reconstructions negatively impacting surgical decision-making. With supratotal resections tied to survival benefit in glioma patients, advanced diff
Externí odkaz:
https://doaj.org/article/a429558c6f1046958e7c1587169153ac
Autor:
Yash Lad, Avesh Jangam, Hayden Carlton, Ma’Moun Abu-Ayyad, Constantinos Hadjipanayis, Robert Ivkov, Brad E. Zacharia, Anilchandra Attaluri
Publikováno v:
Cancers, Vol 15, Iss 18, p 4554 (2023)
Purpose: Develop a treatment planning framework for neurosurgeons treating high-grade gliomas with LITT to minimize the learning curve and improve tumor thermal dose coverage. Methods: Deidentified patient images were segmented using the image segmen
Externí odkaz:
https://doaj.org/article/4936edc368464f7f91c351e04b6820b2
Autor:
Patricia P. Yee, Jianli Wang, Stephen Y. Chih, Dawit G. Aregawi, Michael J. Glantz, Brad E. Zacharia, Krishnamoorthy Thamburaj, Wei Li
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Tumor necrosis is a poor prognostic marker in glioblastoma (GBM) and a variety of other solid cancers. Accumulating evidence supports that necrosis could facilitate tumor progression and resistance to therapeutics. GBM necrosis is typically first det
Externí odkaz:
https://doaj.org/article/9ac329eae6f54a4fb5b3ba44e669db6a
Autor:
Patricia P. Yee, Yiju Wei, Soo-Yeon Kim, Tong Lu, Stephen Y. Chih, Cynthia Lawson, Miaolu Tang, Zhijun Liu, Benjamin Anderson, Krishnamoorthy Thamburaj, Megan M. Young, Dawit G. Aregawi, Michael J. Glantz, Brad E. Zacharia, Charles S. Specht, Hong-Gang Wang, Wei Li
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-22 (2020)
Tumour necrosis is associated with tumour aggressiveness and poor outcomes in patients with glioblastomas, but the underlying mechanisms remain poorly understood. Here, the authors show that in a xenograft mouse model of glioblastoma, tumour-infiltra
Externí odkaz:
https://doaj.org/article/5aa48c67defa41babccc7a4dbd4c5fc0
Autor:
Shervin Taslimi, Karanbir Brar, Yosef Ellenbogen, Jiawen Deng, Winston Hou, Fabio Y. Moraes, Michael Glantz, Brad E. Zacharia, Aaron Tan, Manmeet S. Ahluwalia, Mustafa Khasraw, Gelareh Zadeh, Alireza Mansouri
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundBrain metastases (BM) from non-small-cell lung cancer (NSCLC) are frequent and carry significant morbidity, and current management options include varying local and systemic therapies. Here, we performed a systematic review and network meta
Externí odkaz:
https://doaj.org/article/800fef5f8cd54d518b149439d031f6cb
Autor:
Nicholas G. Zaorsky, Ying Zhang, Leila T. Tchelebi, Heath B. Mackley, Vernon M. Chinchilli, Brad E. Zacharia
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
The risk of fatal stroke is increased in children, adolescent, and young (
Externí odkaz:
https://doaj.org/article/2b15f0b54d994c71a6ae8939cb3ce660