Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Brad C. Stone"'
Autor:
Naveen Yadav, Chaitra Parthiban, Zachary P. Billman, Brad C. Stone, Felicia N. Watson, Kevin Zhou, Tayla M. Olsen, Irene Cruz Talavera, Annette Mariko Seilie, Anya C. Kalata, Jokichi Matsubara, Melanie J. Shears, Rebekah A. Reynolds, Sean C. Murphy
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108489- (2023)
Summary: Liver stage (LS) Plasmodia mature in 2–2.5 days in rodents compared to 5–6 days in humans. Plasmodium-specific CD8+ T cell expansion differs across these varied timespans. To mimic the kinetics of CD8+ T cells of human Plasmodium infecti
Externí odkaz:
https://doaj.org/article/785bc2f629ce4eeb89ee479e29c9795b
Autor:
Tracy Saveria, Chaitra Parthiban, Annette M. Seilie, Colin Brady, Anissa Martinez, Ridhima Manocha, Esha Afreen, Hui Zhao, Ashley Krzeszowski, Jeremy Ferrara, Troy Paddock, James Roberts, Brad C. Stone, Michael Tasch, Sean C. Murphy
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-11 (2022)
Abstract Antibodies against the Plasmodium falciparum circumsporozoite protein (PfCSP) can block hepatocyte infection by sporozoites and protect against malaria. Needle-free vaccination strategies are desirable, yet most PfCSP-targeted vaccines like
Externí odkaz:
https://doaj.org/article/228a3155a40a4ff59c0c8bb17a476cf9
Autor:
Brad C Stone, Arnold Kas, Zachary P Billman, Deborah H Fuller, James T Fuller, Jay Shendure, Sean C Murphy
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153449 (2016)
Development of a subunit vaccine targeting liver-stage Plasmodium parasites requires the identification of antigens capable of inducing protective T cell responses. However, traditional methods of antigen identification are incapable of evaluating T
Externí odkaz:
https://doaj.org/article/f3321b23906047e98f931494234defcb
Autor:
Sean C. Murphy, Reginaldo G. Bastos, Laura B. A. Williams, Brad C. Stone, Lindsay M. Fry, Donald P. Knowles
Publikováno v:
Vaccine
Theileria parva kills over one million cattle annually in sub-Saharan Africa. Parasite genetic complexity, cellular response immunodominance, and bovine MHC diversity have precluded traditional vaccine development. One potential solution is gene gun
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 201(7)
Tissue-resident memory CD8