Zobrazeno 1 - 10
of 147
pro vyhledávání: '"Brad A. Amendt"'
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 26, Iss , Pp 1148-1158 (2021)
Anaplastic thyroid cancer (ATC) is an aggressive, highly metastatic cancer that expresses high levels of the microRNA (miR)-17-92 cluster. We employ an miR inhibitor system to study the function of the different miRs within the miR-17-92 cluster base
Externí odkaz:
https://doaj.org/article/098fbd2b208b4b2cb254042c56488a4d
Autor:
Steven Eliason, Liu Hong, Yan Sweat, Camille Chalkley, Huojun Cao, Qi Liu, Hank Qi, Hongwei Xu, Fenghuang Zhan, Brad A. Amendt
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 9, Pp n/a-n/a (2022)
Background Colorectal cancer (CRC) has a high mortality rate, and therapeutic approaches to treat these cancers are varied and depend on the metabolic state of the tumour. Profiles of CRC tumours have identified several biomarkers, including microRNA
Externí odkaz:
https://doaj.org/article/7b101cdb02934189811dc3809d576987
Autor:
Tadkamol Krongbaramee, Min Zhu, Qingwen Qian, Zeyuan Zhang, Steven Eliason, Yi Shu, Fang Qian, Adil Akkouch, Dan Su, Brad A. Amendt, Ling Yang, Liu Hong
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 23, Iss , Pp 1204-1216 (2021)
The present study was conducted to characterize microRNA-200c (miR-200c) and its regulators in adipogenic differentiation, obesity, and periodontitis in obese subjects (PiOSs), and to determine the therapeutic efficacy of plasmid DNA encoding miR-200
Externí odkaz:
https://doaj.org/article/5dcf0d933c494f0ea7a6449b026654fe
Autor:
Ploy Adisornkanj, Rajit Chanprasit, Steven Eliason, Juan M. Fons, Worrachet Intachai, Sissades Tongsima, Bjorn Olsen, Stefan T. Arold, Chumpol Ngamphiw, Brad A. Amendt, Abigail S. Tucker, Piranit Kantaputra
Publikováno v:
Biology, Vol 12, Iss 3, p 393 (2023)
A mesiodens is a supernumerary tooth located in the midline of the premaxilla. To investigate the genetic cause of mesiodens, clinical and radiographic examination were performed on 23 family members of a two-generation Hmong family. Whole exome sequ
Externí odkaz:
https://doaj.org/article/3b5d7cd0f46f4645b025cb60bbd4d6b0
Autor:
Kathleen R. Markan, Lauren K. Boland, Abdul Qaadir King-McAlpin, Kristin E. Claflin, Michael P. Leaman, Morgan K. Kemerling, Madison M. Stonewall, Brad A. Amendt, James A. Ankrum, Matthew J. Potthoff
Publikováno v:
Molecular Metabolism, Vol 44, Iss , Pp 101148- (2021)
Externí odkaz:
https://doaj.org/article/b63cdee36756479d8cc1b2910233feef
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
The developmental role of Lef-1 in ectodermal organs has been characterized using Lef-1 murine knockout models. We generated a Lef-1 conditional over-expression (COEL) mouse to determine the role of Lef-1 expression in epithelial structures at later
Externí odkaz:
https://doaj.org/article/0a7e05f54e4540be8f56c52509492691
Autor:
Kathleen R. Markan, Lauren K. Boland, Abdul Qaadir King-McAlpin, Kristin E. Claflin, Michael P. Leaman, Morgan K. Kemerling, Madison M. Stonewall, Brad A. Amendt, James A. Ankrum, Matthew J. Potthoff
Publikováno v:
Molecular Metabolism, Vol 36, Iss , Pp - (2020)
Objective: T-box 1 (TBX1) has been identified as a genetic marker of beige adipose tissue. TBX1 is a mesodermal development transcription factor essential for tissue patterning and cell fate determination. However, whether it plays a role in the proc
Externí odkaz:
https://doaj.org/article/ce6dac942e13458db2784760abaedbf8
Autor:
Lord J.J. Gowans, Sophia Cameron-Christie, Rebecca L. Slayton, Tamara Busch, Miguel Romero-Bustillos, Steven Eliason, Mason Sweat, Nara Sobreira, Wenjie Yu, Piranit N. Kantaputra, Elizabeth Wohler, Wasiu Lanre Adeyemo, Salil A. Lachke, Deepti Anand, Collen Campbell, Bernadette K. Drummond, David M. Markie, W. Jansen van Vuuren, L. Jansen van Vuuren, Paul S. Casamassimo, Ronald Ettinger, Arwa Owais, I. van Staden, Brad A. Amendt, Adebowale A. Adeyemo, Jeffrey C. Murray, Stephen P. Robertson, Azeez Butali
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
The etiology of dental anomalies is multifactorial; and genetic and environmental factors that affect the dental lamina have been implicated. We investigated two families of European ancestry in which males were affected by taurodontism, microdontia
Externí odkaz:
https://doaj.org/article/dc7ba625ed2249ce9ac5d6fe72006263
Publikováno v:
Biochemical Society Transactions. 51:841-854
microRNAs (miRs) have been reported over the decades as important regulators in bone development and bone regeneration. They play important roles in maintaining the stem cell signature as well as regulating stem cell fate decisions. Thus, delivering
Autor:
Waheed Awotoye, Joseph Craig Whitt, Byunggil Yoo, Midhat S. Farooqi, Emily G. Farrow, Veerasathpurush Allareddy, Brad A. Amendt, Shankar Rengasamy Venugopalan
Publikováno v:
Journal of Oral Pathology & Medicine. 52:263-270