Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Brad A Grueter"'
Autor:
India A Reddy, Nicholas K Smith, Kevin Erreger, Dipanwita Ghose, Christine Saunders, Daniel J Foster, Brandon Turner, Amanda Poe, Vance L Albaugh, Owen McGuinness, Troy A Hackett, Brad A Grueter, Naji N Abumrad, Charles Robb Flynn, Aurelio Galli
Publikováno v:
PLoS Biology, Vol 16, Iss 7, p e2006682 (2018)
The gut-to-brain axis exhibits significant control over motivated behavior. However, mechanisms supporting this communication are poorly understood. We reveal that a gut-based bariatric surgery chronically elevates systemic bile acids and attenuates
Externí odkaz:
https://doaj.org/article/13174f7186154e20af989ef9ed6ac41c
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41120 (2012)
The use of human embryonic stem cells (hESCs) to repair diseased or injured brain is promising technology with significant humanitarian, societal and economic impact. Parkinson's disease (PD) is a neurological disorder characterized by the loss of mi
Externí odkaz:
https://doaj.org/article/b2d2cedf22c045179597d2cd7033543e
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
The nucleus accumbens (NAc) guides reward-related motivated behavior implicated in pathological behavioral states, including addiction and depression. These behaviors depend on the precise neuromodulatory actions of Gi/o-coupled G-protein-coupled rec
Externí odkaz:
https://doaj.org/article/e89aa25bf4924d6aaa513aa36223badc
Autor:
Nathan D. Winters, Veronika Kondev, Niharika Loomba, Eric Delpire, Brad A. Grueter, Sachin Patel
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112159- (2023)
Summary: The lateral habenula (LHb) encodes aversive states, and its dysregulation is implicated in neuropsychiatric disorders, including depression. The endocannabinoid (eCB) system is a neuromodulatory signaling system that broadly serves to counte
Externí odkaz:
https://doaj.org/article/52dbc67a3ff1466a862e46a5c619f47f
Publikováno v:
Biol Psychiatry
BACKGROUND: Central histamine (HA) signaling modulates diverse cortical and subcortical circuits throughout the brain, including the nucleus accumbens (NAc). The NAc, a key striatal subregion directing reward-related behavior, expresses diverse HA re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4f35ffea7f6fc25f643cf056c1f8706
https://doi.org/10.1016/j.biopsych.2021.10.004
https://doi.org/10.1016/j.biopsych.2021.10.004
Autor:
Kevin M. Manz, Brad A. Grueter, Benjamin C. Coleman, Alexis Jameson, Sachin Patel, Dipanwita Ghose
Publikováno v:
Neuropsychopharmacology
Parvalbumin-expressing fast-spiking interneurons (PV-INs) within feedforward microcircuits in the nucleus accumbens (NAc) coordinate goal-directed motivational behavior. Feedforward inhibition of medium spiny projection neurons (MSNs) is initiated by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17a49913ba9ccb29fd09a67735031c65
https://doi.org/10.1038/s41386-021-01167-3
https://doi.org/10.1038/s41386-021-01167-3
Autor:
Brad A. Grueter, Kevin M. Manz, Carrie A. Grueter, Brenda C Shields, Benjamin C. Coleman, Michael R. Tadross
Publikováno v:
J Neurosci
The nucleus accumbens shell (NAcSh) receives extensive monoaminergic input from multiple midbrain structures. However, little is known how norepinephrine (NE) modulates NAc circuit dynamics. Using a dynamic electrophysiological approach with optogene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b700906a9177b964f3172bcf385b8c8
https://doi.org/10.1523/jneurosci.2420-20.2021
https://doi.org/10.1523/jneurosci.2420-20.2021
Publikováno v:
Biological Psychiatry. 89:588-599
Background Histamine (HA), a wake-promoting monoamine implicated in stress-related arousal states, is synthesized in histidine decarboxylase–expressing hypothalamic neurons of the tuberomammillary nucleus. Histidine decarboxylase–containing varic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb770fffbb50227ad5499b0dcbf1a7fe
https://doi.org/10.1016/j.biopsych.2020.07.023
https://doi.org/10.1016/j.biopsych.2020.07.023
Publikováno v:
Neuroscience
Circadian disruptions, along with altered affective and reward states, are commonly associated with psychiatric disorders. In addition to genetics, the enduring influence of environmental factors in programming neural networks is of increased interes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d272c0d1d5aebedb5dbe75b967449c46
https://doi.org/10.1016/j.neuroscience.2020.12.010
https://doi.org/10.1016/j.neuroscience.2020.12.010
Autor:
Joseph J. Lebowitz, Anne Taylor, Muthukumar Balasubramaniam, Chandravanu Dash, Habibeh Khoshbouei, Jui Pandhare, Fernando Villalta, Carrie A. Grueter, Brad A. Grueter, Bobby Jones
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Scientific Reports
Scientific Reports
Methamphetamine (METH) is a highly addictive psychostimulant that causes long-lasting effects in the brain and increases the risk of developing neurodegenerative diseases. The cellular and molecular effects of METH in the brain are functionally linke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::683a0d77206d0e8014ffa34b23aa748c
https://doaj.org/article/c14ac558b3974efd995809baf00a9f90
https://doaj.org/article/c14ac558b3974efd995809baf00a9f90