Zobrazeno 1 - 10
of 193
pro vyhledávání: '"Brüning-Richardson A"'
Publikováno v:
Journal of Xenobiotics, Vol 14, Iss 2, Pp 613-633 (2024)
Glioblastomas (GBMs) are aggressive and invasive cancers of the brain, associated with high rates of tumour recurrence and poor patient outcomes despite initial treatment. Targeting cell migration is therefore of interest in highly invasive cancers s
Externí odkaz:
https://doaj.org/article/c2af100f158148148348d98b351bf5a0
Publikováno v:
Brain-X, Vol 2, Iss 3, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/bd82caeb92bf4e8dad47e1b1cb106a3c
Autor:
Georgette Tanner, Rhiannon Barrow, Shoaib Ajaib, Muna Al-Jabri, Nazia Ahmed, Steven Pollock, Martina Finetti, Nora Rippaus, Alexander F. Bruns, Khaja Syed, James A. Poulter, Laura Matthews, Thomas Hughes, Erica Wilson, Colin Johnson, Frederick S. Varn, Anke Brüning-Richardson, Catherine Hogg, Alastair Droop, Arief Gusnanto, Matthew A. Care, Luisa Cutillo, David R. Westhead, Susan C. Short, Michael D. Jenkinson, Andrew Brodbelt, Aruna Chakrabarty, Azzam Ismail, Roel G. W. Verhaak, Lucy F. Stead
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-29 (2024)
Abstract Background Glioblastoma (GBM) brain tumors lacking IDH1 mutations (IDHwt) have the worst prognosis of all brain neoplasms. Patients receive surgery and chemoradiotherapy but tumors almost always fatally recur. Results Using RNA sequencing da
Externí odkaz:
https://doaj.org/article/190c474079fc465a883fccd59c89b7b7
Akademický článek
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Publikováno v:
Journal of Xenobiotics; Jun2024, Vol. 14 Issue 2, p613-633, 21p
Autor:
Sophie E. Ketchen, Filomena O. Gamboa-Esteves, Sean E. Lawler, Michal O. Nowicki, Arndt Rohwedder, Sabine Knipp, Sally Prior, Susan C. Short, John E. Ladbury, Anke Brüning-Richardson
Publikováno v:
Biomedicines, Vol 10, Iss 1, p 9 (2021)
Cancer cell invasion is a precondition for tumour metastasis and represents one of the most devastating characteristics of cancer. The development of drugs targeting cell migration, known as migrastatics, may improve the treatment of highly invasive
Externí odkaz:
https://doaj.org/article/b3ae45dc331647029ff3446020ce20a5
Autor:
Julia V. Cockle, Anke Brüning-Richardson, Karen J. Scott, Jill Thompson, Timothy Kottke, Ewan Morrison, Azam Ismail, Angel M. Carcaboso, Ailsa Rose, Peter Selby, Joe Conner, Susan Picton, Susan Short, Richard Vile, Alan Melcher, Elizabeth Ilett
Publikováno v:
Molecular Therapy: Oncolytics, Vol 5, Iss C, Pp 75-86 (2017)
Pediatric high-grade glioma (pHGG) and diffuse intrinsic pontine glioma (DIPG) are invasive tumors with poor survival. Oncolytic virotherapy, initially devised as a direct cytotoxic treatment, is now also known to act via immune-mediated mechanisms.
Externí odkaz:
https://doaj.org/article/6daa5830e2af4d63a0235f4c00e305f7
Autor:
Naomi Egbivwie, Julia V. Cockle, Matthew Humphries, Azzam Ismail, Filomena Esteves, Claire Taylor, Katherine Karakoula, Ruth Morton, Tracy Warr, Susan C. Short, Anke Brüning-Richardson
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
The heterogeneous and invasive nature of pediatric gliomas poses significant treatment challenges, highlighting the importance of identifying novel chemotherapeutic targets. Recently, recurrent Fibroblast growth factor receptor 1 (FGFR1) mutations in
Externí odkaz:
https://doaj.org/article/7f22ae0d10014789b37a5647664dcfc8
Autor:
Georgette Tanner, Rhiannon Barrow, Martina Finetti, Shoaib Ajaib, Nazia Ahmed, Steven Pollock, Nora Rippaus, Alexander F. Bruns, Khaja Syed, James Poulter, Erica Wilson, Colin Johnson, Frederick S. Varn, Anke Brüning-Richardson, Catherine Hogg, Alastair Droop, Arief Gusnanto, Matthew A. Care, Luisa Cutillo, David Westhead, Susan C. Short, Michael D. Jenkinson, Andrew Brodbelt, Aruna Chakrabarty, Azzam Ismail, Roel GW Verhaak, Lucy F. Stead
Glioblastoma (GBM) brain tumours lackingIDH1mutations (IDHwt) have the worst prognosis of all brain neoplasms. Patients receive surgery and chemoradiotherapy but tumours almost always fatally recur. Using RNAseq data from 107 pairs of pre- and post-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3974987cc1bd108afe32b74c23969c12
https://doi.org/10.1101/2023.02.03.526945
https://doi.org/10.1101/2023.02.03.526945
Autor:
A. Rohwedder, S. Knipp, F. O. Esteves, M. Hale, S. E. Ketchen, D. Treanor, A. Brüning-Richardson
Publikováno v:
Interface Focus. 12
Three-dimensional (3D) spheroid cultures are generating increasing interest in cancer research, e.g. for the evaluation of pharmacological effects of novel small molecule inhibitors. This is mainly due to the fact that such 3D structures reflect phys