Identification of a genomic fragment of Mycobacterium tuberculosis responsible for in vivo growth advantage

Autor: Pascopella L, Fm, Collins, Jm, Martin, William Jacobs, Br, Bloom

Publikováno v: Europe PubMed Central

The purpose of this work was to develop a system to identify virulence determinants of M. tuberculosis by genetic complementation. The ability to grow in mouse spleen and/or lung was defined as a potential phenotype for virulence. Enrichment for grow

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::3a69e274d5ccd86d4f218f2ae3c6ee38
https://pubmed.ncbi.nlm.nih.gov/8173811

Development of genetic systems for the mycobacteria

Autor: Wr, Jacobs, Sb, Snapper, Lugosi L, Jekkel A, RACHEL MELTON, Kieser T, Br, Bloom

Publikováno v: Europe PubMed Central

Requisite to a detailed understanding of the molecular basis of bacterial pathogenesis is a genetic system which allows for the transfer, mutation, and expression of specific genes. Genetic analysis of mycobacteria has been exceedingly difficult sinc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4752bd63fa399832b37d6ac539207bc2
http://europepmc.org/abstract/med/2503991

Learning from the Bomb. Reply.

Autor: Bloom BR; Harvard T.H. Chan School of Public Health, Boston, MA bbloom@hsph.harvard.edu.

Publikováno v: The New England journal of medicine [N Engl J Med] 2024 Feb 08; Vol. 390 (6), pp. 580.

Learning from the Bomb.

Autor: Bloom BR; From the Harvard T.H. Chan School of Public Health, Boston.

Publikováno v: The New England journal of medicine [N Engl J Med] 2023 Nov 30; Vol. 389 (22), pp. 2026-2027. Date of Electronic Publication: 2023 Nov 25.

TREM2 macrophages induced by human lipids drive inflammation in acne lesions.

Autor: Do TH; Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA.; Division of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles,, Los Angeles, CA 90095, USA., Ma F; Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA.; Institute for Quantitative and Computational Biosciences-The Collaboratory, University of California, Los Angeles, Los Angeles, CA 90095, USA., Andrade PR; Division of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles,, Los Angeles, CA 90095, USA., Teles R; Division of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles,, Los Angeles, CA 90095, USA., de Andrade Silva BJ; Division of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles,, Los Angeles, CA 90095, USA., Hu C; Institute for Quantitative and Computational Biosciences-The Collaboratory, University of California, Los Angeles, Los Angeles, CA 90095, USA.; Department of Molecular Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA 90095, USA., Espinoza A; Institute for Quantitative and Computational Biosciences-The Collaboratory, University of California, Los Angeles, Los Angeles, CA 90095, USA.; Department of Molecular Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA 90095, USA., Hsu JE; Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Cho CS; Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Kim M; Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Xi J; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., Xing X; Department of Dermatology, University of Michigan, Ann Arbor, MI 48109, USA., Plazyo O; Department of Dermatology, University of Michigan, Ann Arbor, MI 48109, USA., Tsoi LC; Department of Dermatology, University of Michigan, Ann Arbor, MI 48109, USA., Cheng C; Division of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles,, Los Angeles, CA 90095, USA., Kim J; Division of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles,, Los Angeles, CA 90095, USA., Bryson BD; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., O'Neill AM; Department of Dermatology, University of California San Diego, La Jolla, CA 92093, USA., Colonna M; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., Gudjonsson JE; Department of Dermatology, University of Michigan, Ann Arbor, MI 48109, USA., Klechevsky E; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., Lee JH; Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Gallo RL; Department of Dermatology, University of California San Diego, La Jolla, CA 92093, USA., Bloom BR; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA., Pellegrini M; Institute for Quantitative and Computational Biosciences-The Collaboratory, University of California, Los Angeles, Los Angeles, CA 90095, USA.; Department of Molecular Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA 90095, USA., Modlin RL; Division of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles,, Los Angeles, CA 90095, USA.; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA.

Publikováno v: Science immunology [Sci Immunol] 2022 Jul 22; Vol. 7 (73), pp. eabo2787. Date of Electronic Publication: 2022 Jul 22.