Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Bozena Michniak-Kohn"'
Publikováno v:
AAPS Open, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract This research study involves the development of an olanzapine (OLZ) formulation using various chemical penetration enhancers (CPEs) for transdermal delivery. The aim of this study was to obtain the initial data needed about the effects of va
Externí odkaz:
https://doaj.org/article/ce333515012140af83ffe10fc3f32756
Publikováno v:
Scientia Pharmaceutica, Vol 92, Iss 2, p 29 (2024)
Thymoquinone (TQ), a bioactive compound found in Nigella sativa seeds, possesses diverse therapeutic properties for skin conditions. However, formulating TQ presents challenges due to its hydrophobic nature and chemical instability, which hinder its
Externí odkaz:
https://doaj.org/article/f88bb61469964a69a78bf178306c34c5
Autor:
Khea Wolff, Keyaara Robinson, Nanjoo Suh, Bozena Michniak-Kohn, Michael Goedken, Marianne Polunas, Ilya Raskin
Publikováno v:
Phytomedicine Plus, Vol 3, Iss 4, Pp 100479- (2023)
Background: Moringa (Moringa oleifera Lam.) seed extract (MSE) and its primary bioactive compound, moringa isothiocyanate-1(MIC-1), mitigate inflammation, oxidative stress, diabetes, and cancer in the in vivo rodent models following oral application.
Externí odkaz:
https://doaj.org/article/8d877aa15c8a4824aa5e37df1dfbb8af
Autor:
Joachim Kohn, Bozena Michniak-Kohn
Publikováno v:
Journal of Medical Science, Vol 92, Iss 3 (2023)
Much of the priorities in drug delivery research are focused on targeted drug delivery for cancer therapies and a wide range of controlled drug release systems for commonly used active pharmaceutical ingredients (APIs). In this “thousand words arti
Externí odkaz:
https://doaj.org/article/fc3d7a7320354232aa039986a24b30f6
Autor:
Bozena Michniak-Kohn, Joachim Kohn
Publikováno v:
Journal of Medical Science, Vol 92, Iss 3 (2023)
Background. The skin’s uppermost layer, the stratum corneum is a very effective barrier against the penetration of compounds including pharmaceuticals and cosmetic actives. To deliver higher amounts of drugs into the skin layers or to deliver drugs
Externí odkaz:
https://doaj.org/article/3a5cc65c33174dc7a2308fe22b8f286a
Autor:
Namrata S. Matharoo, Harsha T. Garimella, Carrie German, Andrzej J. Przekwas, Bozena Michniak-Kohn
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15118 (2023)
The administration of therapeutic drugs through dermal routes, such as creams and ointments, has emerged as an increasingly popular alternative to traditional delivery methods, such as tablets and injections. In the context of drug development, it is
Externí odkaz:
https://doaj.org/article/988b0933aba4449390ed5fb037aa6fbb
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 183 (2023)
Oxcarbazepine (OXC) is an anticonvulsant drug, indicated for the treatment of the neurological disorder, epilepsy. The objective of the present study was to evaluate the transdermal delivery of OXC from microemulsions using different penetration enha
Externí odkaz:
https://doaj.org/article/94c25b7b4933408e8721b12b061d3d57
Autor:
Vinam Puri, Anna Froelich, Parinbhai Shah, Shernelle Pringle, Kevin Chen, Bozena Michniak-Kohn
Publikováno v:
Pharmaceutics, Vol 14, Iss 10, p 2170 (2022)
Superficial fungal diseases of the skin and nails are an increasingly common occurrence globally, requiring effective topical treatment to avoid systemic adverse effects. Polymeric nanoparticles have demonstrated sustained and effective drug delivery
Externí odkaz:
https://doaj.org/article/555634ecfef040febb6e4d157a0dd2fb
Publikováno v:
Pharmaceutics, Vol 14, Iss 10, p 2204 (2022)
The fungal disease of the nail, onychomycosis, which is also the most prevalent nail disturbance, demands effective topical treatment options considering the possible adverse effects of systemic antifungal therapy. The current work is focused on deve
Externí odkaz:
https://doaj.org/article/953de927276e47cc90ee8baa5c434081
Autor:
Anika Haq, Bozena Michniak-Kohn
Publikováno v:
Drug Delivery, Vol 25, Iss 1, Pp 1943-1949 (2018)
Thymoquinone (TQ) is a quinone-based phytochemical that was first identified in 1963 in Nigella sativa (black cumin seed) by El-Dakhakhany. Based on the ideal characteristics of transdermal delivery, TQ is potentially an attractive candidate for tran
Externí odkaz:
https://doaj.org/article/931dd802eb31478dae01df1a6590163c