Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Bozena Korczak"'
Autor:
Ian McGowan, Monika Tomaszewska-Kiecana, Beata Kosak, Jarret Engstrom, Bozena Korczak, Oliver Hartley, Niko Tzakis
Publikováno v:
AIDS research and human retroviruses. 37(6)
OB-002 is an extremely potent CCR5 antagonist that has previously been shown to completely block transmission in a nonhuman primate model of HIV infection. The purpose of this study was to characterize the safety, acceptability, and pharmacokinetic p
Autor:
Sachchidanand Tiwari, Harpal Singh, Neha Mehrotra, Surender Kharbanda, Bozena Korczak, Sireesh Appajosyula, Steve Laumas, Anees Mohammad
Publikováno v:
Cancer Research. 81:3107-3107
Small cell lung cancer (SCLC) is a highly malignant form of lung cancer that accounts for 15% of lung cancer cases. The tumor has a tendency to disseminate early resulting in ~ 85% patients being diagnosed with extensive stage disease (ES-SCLC). Chem
Autor:
Sachchidanand Tiwari, Bozena Korczak, Steve Laumas, Sireesh Appajosyula, Neha Mehrotra, Anees Mohammad, Harpal Singh, Surender Kharbanda
Publikováno v:
Cancer Research. 81:3082-3082
Triple negative breast cancer (TNBC) is an aggressive subtype with limited treatment options and a worse clinical outcome as compared with other breast cancer subtypes. Doxorubicin (DOX) is considered to be one of the most effective agents in the tre
Autor:
Sara Peleg, Galina Bernstein, Patrick M. Dolan, Gary H. Posner, Mehmet Kahraman, Thomas W. Kensler, Samuel S. Chuang, Uttam Saha, Sandra Sinishtaj, Bozena Korczak
Publikováno v:
Journal of Medicinal Chemistry. 47:6854-6863
A dozen 24-sulfoximine analogues of the hormone 1alpha,25-dihydroxyvitamin D(3) were prepared, differing not only at the stereogenic sulfoximine stereocenter but also at the A-ring. Although these sulfoximines were not active transcriptionally and we
Autor:
Byung Chul Suh, Jae Kyoo Lee, Samuel S. Chuang, Mark A. Hatcher, Thomas W. Kensler, Tanzina Labonte, Hong Woon Yang, Glenville Jones, Heung Bae Jeon, Patrick M. Dolan, Kenneth R. Crawford, Sara Peleg, Bozena Korczak, Anqi Zhang, Mehmet Kahraman, Hongbin Li, Aimee R. Usera, Uttam Saha, Gary H. Posner
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. :5-12
The new 24-phenylsulfone 4a, a low-calcemic analog of the natural hormone 1alpha,25-dihydroxyvitamin D(3), is a potent (IC(50) = 28nM) and highly selective inhibitor of the human 24-hydroxylase enzyme CYP24.
Autor:
Christian F. Helvig, Jay A. White, Martin Petkovich, Heather Ramshaw, Bozena Korczak, Jan Wisniewski, Ma'an Amad, Mohammed Taimi
Publikováno v:
Journal of Biological Chemistry. 279:77-85
Retinoids are potent regulators of cell proliferation, cell differentiation, and morphogenesis and are important therapeutic agents in oncology and dermatology. The gene regulatory activity of endogenous retinoids is effected primarily by retinoic ac
Publikováno v:
Scopus-Elsevier
UDP-GlcNAc: Manalpha1-6Manbeta-R beta1-6 N-acetylglucosaminyltransferase V (EC 2.4.1.155, GlcNAc-TV) is a Golgi enzyme that substitutes the trimannosyl core in the biosynthetic pathway for complex-type N-linked glycans. GlcNAc-TV activity is regulate
Autor:
Ian J. Sas, René Roy, Rob Donovan, James W. Dennis, Eric G. Berger, Alessandro Datti, Qingquan Wu, Bozena Korczak, Myung-Gi Baek
Publikováno v:
Glycoconjugate Journal. 16:607-615
Glycosyltransferases mediate changes in glycosylation patterns which, in turn, may affect the function of glycoproteins and/or glycolipids and, further downstream, processes of development, differentiation, transformation and cell-cell recognition. S
Autor:
Heather Ramshaw, Samuel S. Chuang, Martin Petkovich, Bozena Korczak, Andrew H. Collop, Jay A. White, Mohammed Taimi, Ma'an Amad, Glenville Jones, Christian F. Helvig
Publikováno v:
The Journal of biological chemistry. 279(8)
Long chain fatty acids have recently emerged as critical signaling molecules in neuronal, cardiovascular, and renal processes, yet little is presently known about the precise mechanisms controlling their tissue distribution and bioactivation. We have
Malignant transformation is accompanied by altered cell surface glycosylation. N-Linked oligosaccharides carrying beta1-6GlcNAc branches are associated with tumor invasion and metastasis. Therefore, compounds that can enter cells and block biosynthes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11f47c0b9e58db527d68a009d343a1bf
http://hdl.handle.net/11391/20102
http://hdl.handle.net/11391/20102