Zobrazeno 1 - 10
of 655
pro vyhledávání: '"Bozena Kaminska"'
Autor:
Malgorzata Perycz, Michal J. Dabrowski, Marta Jardanowska-Kotuniak, Adria-Jaume Roura, Bartlomiej Gielniewski, Karolina Stepniak, Michał Dramiński, Iwona A. Ciechomska, Bozena Kaminska, Bartosz Wojtas
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-29 (2024)
Abstract The RE1-silencing transcription factor (REST) acts either as a repressor or activator of transcription depending on the genomic and cellular context. REST is a key player in brain cell differentiation by inducing chromatin modifications, inc
Externí odkaz:
https://doaj.org/article/9e43803f2e9b471f8242922568240305
Autor:
Marta Maleszewska, Kamil Wojnicki, Jakub Mieczkowski, Sylwia K. Król, Karol Jacek, Magdalena Śmiech, Marta Kocyk, Iwona A. Ciechomska, Mateusz Bujko, Janusz Siedlecki, Katarzyna Kotulska, Wiesława Grajkowska, Małgorzata Zawadzka, Bozena Kaminska
Publikováno v:
Cell Death and Disease, Vol 15, Iss 3, Pp 1-10 (2024)
Abstract Glioblastoma (GBM) is the most common and lethal brain tumor in adults. Due to its fast proliferation, diffusive growth and therapy resistance survival times are less than two years for patients with IDH-wildtype GBM. GBM is noted for the co
Externí odkaz:
https://doaj.org/article/39653d30495f4f958da04fe349022e31
Autor:
Katarzyna B. Leszczynska, Amanda Freitas-Huhtamäki, Chinchu Jayaprakash, Monika Dzwigonska, Francisca N.L. Vitorino, Cynthia Horth, Kamil Wojnicki, Bartlomiej Gielniewski, Paulina Szadkowska, Beata Kaza, Javad Nazarian, Maciej K. Ciolkowski, Joanna Trubicka, Wieslawa Grajkowska, Benjamin A. Garcia, Jacek Majewski, Bozena Kaminska, Jakub Mieczkowski
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113707- (2024)
Summary: Diffuse intrinsic pontine gliomas (DIPGs) are deadly pediatric brain tumors, non-resectable due to brainstem localization and diffusive growth. Over 80% of DIPGs harbor a mutation in histone 3 (H3.3 or H3.1) resulting in a lysine-to-methioni
Externí odkaz:
https://doaj.org/article/590589af8239422c9bd340fc8f43c4fa
Autor:
Marcin Kortylewski, Behnam Badie, Amy Heimberger, Chia-Yang Hung, Bozena Kaminska, Xiaowei Zhang, Elaine Kang, Karol Jacek, Chunsong Yu, Susanta Hui
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/541b803a3ec7476cb22509119af83149
Autor:
Katarzyna B. Leszczynska, Monika Dzwigonska, Hala Estephan, Jutta Moehlenbrink, Elizabeth Bowler, Amato J. Giaccia, Jakub Mieczkowski, Bozena Kaminska, Ester M. Hammond
Publikováno v:
Molecular Oncology, Vol 17, Iss 7, Pp 1173-1191 (2023)
Local hypoxia occurs in most solid tumors and is associated with aggressive disease and therapy resistance. Widespread changes in gene expression play a critical role in the biological response to hypoxia. However, most research has focused on hypoxi
Externí odkaz:
https://doaj.org/article/322ae7bae5474bcc992e7a2cd94f8ce2
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-12 (2023)
Abstract Most of anti-tumour therapies eliminate neoplastic cells by introducing DNA damage which ultimately triggers cell death. These effects are counteracted by activated DNA repair pathways to sustain tumour proliferation capacity. RECQL helicase
Externí odkaz:
https://doaj.org/article/5dd9b8f3862347d98f96346d2d2ff852
Autor:
Adria-Jaume Roura, Paulina Szadkowska, Katarzyna Poleszak, Michal J. Dabrowski, Aleksandra Ellert-Miklaszewska, Kamil Wojnicki, Iwona A. Ciechomska, Karolina Stepniak, Bozena Kaminska, Bartosz Wojtas
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-22 (2023)
Abstract Background Glioblastoma (GBM, WHO grade IV) is an aggressive, primary brain tumor. Despite extensive tumor resection followed by radio- and chemotherapy, life expectancy of GBM patients did not improve over decades. Several studies reported
Externí odkaz:
https://doaj.org/article/7137ac18dafd4e8eaf59d8af42507495
Publikováno v:
F1000Research, Vol 11 (2023)
Glioblastoma (GBM), a deadly brain tumor, is still one of a few lasting challenges of contemporary oncology. Current therapies fail to significantly improve patient survival due to GBM tremendous genetic, transcriptomic, immunological, and sex-depend
Externí odkaz:
https://doaj.org/article/163be510125549e18d2a4405e59c9cfb
Autor:
Natalia Ochocka, Pawel Segit, Kamil Wojnicki, Salwador Cyranowski, Julian Swatler, Karol Jacek, Wiesława Grajkowska, Bozena Kaminska
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111971- (2023)
Summary: Malignant gliomas are aggressive, hard-to-treat brain tumors. Their tumor microenvironment is massively infiltrated by myeloid cells, mostly brain-resident microglia, bone marrow (BM)-derived monocytes/macrophages, and dendritic cells that s
Externí odkaz:
https://doaj.org/article/97f3576075b6453a89a4fb80337392db
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-32 (2021)
Abstract Glioma represents a fast proliferating and highly invasive brain tumor which is resistant to current therapies and invariably recurs. Despite some advancements in anti-glioma therapies, patients’ prognosis remains poor. Toll-like receptors
Externí odkaz:
https://doaj.org/article/4b5ba000fda8499e8076c1c19317a597