Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Bozena Bruhn-Olszewska"'
Autor:
Małgorzata Rydzanicz, Pawel Olszewski, Darek Kedra, Hanna Davies, Natalia Filipowicz, Bozena Bruhn‐Olszewska, Marco Cavalli, Krzysztof Szczałuba, Marlena Młynek, Marcin M. Machnicki, Piotr Stawiński, Grażyna Kostrzewa, Paweł Krajewski, Dariusz Śladowski, Krystyna Chrzanowska, Jan P. Dumanski, Rafał Płoski
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 9, Iss 1, Pp n/a-n/a (2021)
Abstract Background Phenotypically discordant monozygotic twins (PDMZTs) offer a unique opportunity to study post‐zygotic genetic variation and provide insights into the linkage between genotype and phenotype. We report a comprehensive analysis of
Externí odkaz:
https://doaj.org/article/853c2803d00245c78a246f0a79689b02
Autor:
Magdalena Wójcik, Ulana Juhas, Elyas Mohammadi, Jonas Mattisson, Kinga Drężek-Chyła, Edyta Rychlicka-Buniowska, Bożena Bruhn-Olszewska, Hanna Davies, Katarzyna Chojnowska, Paweł Olszewski, Michał Bieńkowski, Michał Jankowski, Olga Rostkowska, Andrzej Hellmann, Rafał Pęksa, Jacek Kowalski, Marek Zdrenka, Jarek Kobiela, Wojciech Zegarski, Wojciech Biernat, Łukasz Szylberg, Piotr Remiszewski, Jakub Mieczkowski, Natalia Filipowicz, Jan P. Dumanski
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Male sex is a risk factor for colorectal cancer (CRC) with higher illness burden and earlier onset. Thus, we hypothesized that loss of chromosome Y (LOY) in the tumor micro-environment (TME) might be involved in oncogenesis. Previous studies
Externí odkaz:
https://doaj.org/article/7d9a04b0e6d44884bfeda7d025cf4b9a
Autor:
Jonas Mattisson, Jonatan Halvardson, Hanna Davies, Bożena Bruhn-Olszewska, Paweł Olszewski, Marcus Danielsson, Josefin Bjurling, Amanda Lindberg, Ammar Zaghlool, Edyta Rychlicka-Buniowska, Jan P. Dumanski, Lars A. Forsberg
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Background Mosaic loss of chromosome Y (LOY) in leukocytes is the most prevalent somatic aneuploidy in aging humans. Men with LOY have increased risks of all-cause mortality and the major causes of death, including many forms of cancer. It h
Externí odkaz:
https://doaj.org/article/3fb79618f8b24d1694b937e0dfc03697
Autor:
Krystyna H. Chrzanowska, Natalia Filipowicz, Dariusz Śladowski, Marcin M Machnicki, Piotr Stawiński, Hanna Davies, Paweł Olszewski, Krzysztof Szczałuba, Bozena Bruhn-Olszewska, Darek Kedra, Paweł Krajewski, Marco Cavalli, Jan P. Dumanski, Grażyna Kostrzewa, Rafał Płoski, Małgorzata Rydzanicz, Marlena Młynek
Publikováno v:
Molecular Genetics & Genomic Medicine
Molecular Genetics & Genomic Medicine, Vol 9, Iss 1, Pp n/a-n/a (2021)
Molecular Genetics & Genomic Medicine, Vol 9, Iss 1, Pp n/a-n/a (2021)
Background Phenotypically discordant monozygotic twins (PDMZTs) offer a unique opportunity to study post‐zygotic genetic variation and provide insights into the linkage between genotype and phenotype. We report a comprehensive analysis of a pair of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::694d01f925c889b50b9393d7bf331147
https://doi.org/10.1002/mgg3.1526
https://doi.org/10.1002/mgg3.1526
Autor:
Bozena Bruhn-Olszewska, Kevin M. Lawrence, Rebecca Jones, Thomas R. Jackson, Ian C. Locke, Rachael L. Baylie, Stephen M. Richardson, Paul A. Townsend, Tim N. Board, Benjamin Abbott
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Lawrence, K, Jones, R, Jackson, T, Baylie, R, Abbott, B, Bruhn-Olszewska, B, Board, T N, Locke, I C, Richardson, S & Townsend, P 2017, ' Chondroprotection by urocortin involves blockade of the mechanosensitive ion channel Piezo1. ', Scientific Reports, vol. 7, 5147 . https://doi.org/10.1038/s41598-017-04367-4
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Lawrence, K, Jones, R, Jackson, T, Baylie, R, Abbott, B, Bruhn-Olszewska, B, Board, T N, Locke, I C, Richardson, S & Townsend, P 2017, ' Chondroprotection by urocortin involves blockade of the mechanosensitive ion channel Piezo1. ', Scientific Reports, vol. 7, 5147 . https://doi.org/10.1038/s41598-017-04367-4
Osteoarthritis (OA) is characterised by progressive destruction of articular cartilage and chondrocyte cell death. Here, we show the expression of the endogenous peptide urocortin1 (Ucn1) and two receptor subtypes, CRF-R1 and CRF-R2, in primary human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f93a98be25117aa432604971473cad82
http://europepmc.org/articles/PMC5505992
http://europepmc.org/articles/PMC5505992
Autor:
Bożena Bruhn-Olszewska, Hanna Davies, Daniil Sarkisyan, Ulana Juhas, Edyta Rychlicka-Buniowska, Magdalena Wójcik, Monika Horbacz, Marcin Jąkalski, Paweł Olszewski, Jakub O. Westholm, Agata Smialowska, Karol Wierzba, Åsa Torinsson Naluai, Niklas Jern, Lars-Magnus Andersson, Josef D. Järhult, Natalia Filipowicz, Eva Tiensuu Janson, Sten Rubertsson, Miklós Lipcsey, Magnus Gisslén, Michael Hultström, Robert Frithiof, Jan P. Dumanski
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-14 (2022)
Abstract Background The COVID-19 pandemic, which has a prominent social and economic impact worldwide, shows a largely unexplained male bias for the severity and mortality of the disease. Loss of chromosome Y (LOY) is a risk factor candidate in COVID
Externí odkaz:
https://doaj.org/article/47e00c830df04f0b876d13cf816381e5
Autor:
Katarzyna Potrykus, Nathan E. Thomas, Bożena Bruhn-Olszewska, Michał Sobala, Maciej Dylewski, Tamara James, Michael Cashel
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
The Mesh1 class of hydrolases found in bacteria, metazoans and humans was discovered as able to cleave an intact pyrophosphate residue esterified on the 3′hydroxyl of (p)ppGpp in a Mn2+ dependent reaction. Here, thin layer chromatography (TLC) qual
Externí odkaz:
https://doaj.org/article/6ce7aa90bc7e491cb21d7576de2d686e
Autor:
Bożena Bruhn-Olszewska, Anna Korzon-Burakowska, Grzegorz Węgrzyn, Joanna Jakóbkiewicz-Banecka
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Charcot arthropathy is one of the most serious complications of diabetic foot syndrome that leads to amputation of the affected limb. Since there is no cure for Charcot arthropathy, early diagnosis and implementation preventive care are the
Externí odkaz:
https://doaj.org/article/a0749f39c6fa4cefb935b5c24a69437d
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
In bacteria, the so-called stringent response is responsible for adaptation to changing environmental conditions. This response is mediated by guanosine derivatives [(p)ppGpp], synthesized by either large mono-functional RelA or bi-functional SpoT (s
Externí odkaz:
https://doaj.org/article/b966185807e043bb8d832a261b299785