Ectopically expressed Airn lncRNA deposits Polycomb with a potency that rivals Xist .

Autor: Trotman JB, Braceros AK, Bischoff SR, Murvin MM, Boyson SP, Cherney RE, Eberhard QE, Abrash EW, Cowley DO, Calabrese JM

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 May 09. Date of Electronic Publication: 2023 May 09.

Forward genetic screen of homeostatic antibody levels in the Collaborative Cross identifies MBD1 as a novel regulator of B cell homeostasis.

Autor: Hampton BK; Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Plante KS; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Whitmore AC; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Linnertz CL; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Madden EA; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Noll KE; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Boyson SP; Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Parotti B; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Xenakis JG; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Bell TA; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Hock P; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Shaw GD; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., de Villena FP; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina, United States of America., Ferris MT; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Heise MT; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina, United States of America.

Publikováno v: PLoS genetics [PLoS Genet] 2022 Dec 27; Vol. 18 (12), pp. e1010548. Date of Electronic Publication: 2022 Dec 27 (Print Publication: 2022).

Functional Roles of Bromodomain Proteins in Cancer.

Autor: Boyson SP; Department of Pharmaceutical Sciences, Albany College of Pharmacy and Health Sciences, Colchester, VT 05446, USA.; Department of Pharmacology, Larner College of Medicine, University of Vermont, Burlington, VT 05405, USA., Gao C; Department of Biomedical and Health Sciences, University of Vermont, Burlington, VT 05405, USA., Quinn K; Department of Pharmacology, Larner College of Medicine, University of Vermont, Burlington, VT 05405, USA.; Department of Biomedical and Health Sciences, University of Vermont, Burlington, VT 05405, USA., Boyd J; Department of Biomedical and Health Sciences, University of Vermont, Burlington, VT 05405, USA., Paculova H; Department of Biomedical and Health Sciences, University of Vermont, Burlington, VT 05405, USA., Frietze S; Department of Biomedical and Health Sciences, University of Vermont, Burlington, VT 05405, USA.; University of Vermont Cancer Center, Burlington, VT 05405, USA., Glass KC; Department of Pharmaceutical Sciences, Albany College of Pharmacy and Health Sciences, Colchester, VT 05446, USA.; Department of Pharmacology, Larner College of Medicine, University of Vermont, Burlington, VT 05405, USA.; University of Vermont Cancer Center, Burlington, VT 05405, USA.

Publikováno v: Cancers [Cancers (Basel)] 2021 Jul 19; Vol. 13 (14). Date of Electronic Publication: 2021 Jul 19.

The BRPF1 bromodomain is a molecular reader of di-acetyllysine.

Autor: Obi JO; Department of Pharmaceutical Sciences, Albany College of Pharmacy and Health Sciences, Colchester, VT, 05446, USA., Lubula MY; Department of Pharmaceutical Sciences, Albany College of Pharmacy and Health Sciences, Colchester, VT, 05446, USA., Cornilescu G; National Magnetic Resonance Facility at Madison and Department of Biochemistry, University of Wisconsin-Madison, Madison, WI, 53706, USA., Henrickson A; Department of Chemistry and Biochemistry, University of Lethbridge, Lethbridge, Alberta, CA, Canada., McGuire K; Department of Pharmaceutical Sciences, Albany College of Pharmacy and Health Sciences, Colchester, VT, 05446, USA., Evans CM; Department of Pharmaceutical Sciences, Albany College of Pharmacy and Health Sciences, Colchester, VT, 05446, USA., Phillips M; Department of Pharmaceutical Sciences, Albany College of Pharmacy and Health Sciences, Colchester, VT, 05446, USA., Boyson SP; Department of Pharmaceutical Sciences, Albany College of Pharmacy and Health Sciences, Colchester, VT, 05446, USA., Demeler B; Department of Chemistry and Biochemistry, University of Lethbridge, Lethbridge, Alberta, CA, Canada., Markley JL; National Magnetic Resonance Facility at Madison and Department of Biochemistry, University of Wisconsin-Madison, Madison, WI, 53706, USA., Glass KC; Department of Pharmaceutical Sciences, Albany College of Pharmacy and Health Sciences, Colchester, VT, 05446, USA.

Publikováno v: Current research in structural biology [Curr Res Struct Biol] 2020; Vol. 2, pp. 104-115. Date of Electronic Publication: 2020 May 12.