Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Boys, Richard J."'
Autor:
Fisher, Holly F., Boys, Richard J., Gillespie, Colin S., Proctor, Carole J., Golightly, Andrew
The presence of protein aggregates in cells is a known feature of many human age-related diseases, such as Huntington's disease. Simulations using fixed parameter values in a model of the dynamic evolution of expanded polyglutamine (PolyQ) proteins i
Externí odkaz:
http://arxiv.org/abs/2009.07594
The analysis of rank ordered data has a long history in the statistical literature across a diverse range of applications. In this paper we consider the Extended Plackett-Luce model that induces a flexible (discrete) distribution over permutations. T
Externí odkaz:
http://arxiv.org/abs/2002.05953
Publikováno v:
Systematic Biology, 2018 Mar 01. 67(2), 320-366.
Externí odkaz:
https://www.jstor.org/stable/26581939
Ranked data arise in many areas of application ranging from the ranking of up-regulated genes for cancer to the ranking of academic statistics journals. Complications can arise when rankers do not report a full ranking of all entities; for example, t
Externí odkaz:
http://arxiv.org/abs/1806.11392
Autor:
Boys, Richard J., Philipson, Peter M.
Ranking sportsmen whose careers took place in different eras is often a contentious issue and the topic of much debate. In this paper we focus on cricket and examine what conclusions may be drawn about the ranking of Test batsmen using data on battin
Externí odkaz:
http://arxiv.org/abs/1806.05496
Stochastic kinetic models are often used to describe complex biological processes. Typically these models are analytically intractable and have unknown parameters which need to be estimated from observed data. Ideally we would have measurements on al
Externí odkaz:
http://arxiv.org/abs/1803.04246
Autor:
Gillespie, Colin S., Boys, Richard J.
Stochastic process models are now commonly used to analyse complex biological, ecological and industrial systems. Increasingly there is a need to deliver accurate estimates of model parameters and assess model fit by optimizing the timing of measurem
Externí odkaz:
http://arxiv.org/abs/1803.04254
Autor:
Heaps, Sarah E., Nye, Tom M. W., Boys, Richard J., Williams, Tom A., Cherlin, Svetlana, Embley, T. Martin
Phylogenetics uses alignments of molecular sequence data to learn about evolutionary trees relating species. Along branches, sequence evolution is modelled using a continuous-time Markov process characterised by an instantaneous rate matrix. Early mo
Externí odkaz:
http://arxiv.org/abs/1702.05972
We consider the task of generating discrete-time realisations of a nonlinear multivariate diffusion process satisfying an It\^o stochastic differential equation conditional on an observation taken at a fixed future time-point. Such realisations are t
Externí odkaz:
http://arxiv.org/abs/1509.09120
Stochastic differential equations (SDEs) provide a natural framework for modelling intrinsic stochasticity inherent in many continuous-time physical processes. When such processes are observed in multiple individuals or experimental units, SDE driven
Externí odkaz:
http://arxiv.org/abs/1507.06807