Reactive astrocytes generated from human iPSC are pro-inflammatory and display altered metabolism

Autor: McComish, Sarah F., O’Sullivan, Julia, Copas, Adina Mac Mahon, Imiolek, Magdalena, Boyle, Noreen T., Crompton, Lucy A., Lane, Jon D., Caldwell, Maeve A.

Publikováno v: In Experimental Neurology December 2024 382

First-in-class thyrotropin-releasing hormone (TRH)-based compound binds to a pharmacologically distinct TRH receptor subtype in human brain and is effective in neurodegenerative models

Autor: Kelly, Julie A., Boyle, Noreen T., Cole, Natalie, Slator, Gillian R., Colivicchi, M. Alessandra, Stefanini, Chiara, Gobbo, Oliviero L., Scalabrino, Gaia A., Ryan, Sinead M., Elamin, Marwa, Walsh, Cathal, Vajda, Alice, Goggin, Margaret M., Campbell, Matthew, Mash, Deborah C., O'Mara, Shane M., Brayden, David J., Callanan, John J., Tipton, Keith F., Della Corte, Laura, Hunter, Jackie, O'Boyle, Kathy M., Williams, Carvell H., Hardiman, Orla

Publikováno v: In Neuropharmacology February 2015 89:193-203

Ischemic brain injury: A consortium analysis of key factors involved in mesenchymal stem cell-mediated inflammatory reduction

Autor: McGuckin, Colin P., Jurga, Marcin, Miller, Anne-Marie, Sarnowska, Anna, Wiedner, Marc, Boyle, Noreen T., Lynch, Marina A., Jablonska, Anna, Drela, Katarzyna, Lukomska, Barbara, Domanska-Janik, Krystyna, Kenner, Lukas, Moriggl, Richard, Degoul, Olivier, Perruisseau-Carrier, Claire, Forraz, Nico

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Psychological stress suppresses innate IFN-γ production via glucocorticoid receptor activation: Reversal by the anxiolytic chlordiazepoxide

Autor: Curtin, Niamh M., Boyle, Noreen T., Mills, Kingston H.G., Connor, Thomas J.

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Induction of protein citrullination and auto-antibodies production in murine exposed to nickel

Autor: Mohamed, Bashir M., Boyle, Noreen T., Schinwald, Anja, Murer, Bruno, Ward, Ronan, Mahfoud, Omar K., Rakovich, Tatsiana, Crosbie-Staunton, Kieran, Gray, Steven G., Donaldson, Ken, YuriVolkov, Prina-Mello, Adriele

Publikováno v: Mohamed, B M, Boyle, N T, Schinwald, A, Murer, B, Ward, R, Mahfoud, O K, Rakovich, T, Crosbie-Staunton, K, Gray, S G, Donaldson, K, YuriVolkov & Prina-Mello, A 2018, ' Induction of protein citrullination and auto-antibodies production in murine exposed to nickel ', Scientific Reports, vol. 8, 679 . https://doi.org/10.1038/s41598-017-19068-1

Citrullination, or the post-translational deimination of polypeptide-bound arginine, is involved in several pathological processes in the body, including autoimmunity and tumorigenesis. Recent studies have shown that nanomaterials can trigger protein

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https://www.pure.ed.ac.uk/ws/files/53337136/Donaldson_K_Induction_of_protein....pdf