Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Boyko Kabakchiev"'
Autor:
Simon Sutcliffe, Shirin Kalyan, Jim Pankovich, Jenny M. H. Chen, Rashieda Gluck, Darby Thompson, Momir Bosiljcic, Mark Bazett, Richard N. Fedorak, Remo Panaccione, Jeffrey Axler, John K. Marshall, David W. Mullins, Boyko Kabakchiev, Dermot P. B. McGovern, Julie Jang, Andrew Coldman, Gillian Vandermeirsch, Brian Bressler, Hal Gunn
Publikováno v:
Frontiers in Medicine, Vol 6 (2019)
Background: Current Crohn's disease (CD) therapies focus on suppressing immune function and come with consequent risk, such as infection and cancer. Notwithstanding, most CD patients still experience disease progression. There is a need for new CD tr
Externí odkaz:
https://doaj.org/article/16ebca018dc54a3db4c12643872ffe03
Autor:
Andrea D Tyler, Natalie Knox, Boyko Kabakchiev, Raquel Milgrom, Richard Kirsch, Zane Cohen, Robin S McLeod, David S Guttman, Denis O Krause, Mark S Silverberg
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e66934 (2013)
INTRODUCTION: Inflammatory complications following ileal pouch-anal anastomosis (IPAA) for ulcerative colitis (UC) are common and thought to arise through mechanisms similar to de novo onset inflammatory bowel disease. The aim of this study was to de
Externí odkaz:
https://doaj.org/article/70f80c6b0c414eabb81274f87ddba89e
Autor:
Boyko Kabakchiev, Dan Turner, Jeffrey Hyams, David Mack, Neal Leleiko, Wallace Crandall, James Markowitz, Anthony R Otley, Wei Xu, Pingzhao Hu, Anne M Griffiths, Mark S Silverberg
Publikováno v:
PLoS ONE, Vol 5, Iss 9 (2010)
Microarray analysis of RNA expression allows gross examination of pathways operative in inflammation. We aimed to determine whether genes expressed in whole blood early following initiation of intravenous corticosteroid treatment can be associated wi
Externí odkaz:
https://doaj.org/article/a3d7b9aacfb34159b368c94cbd86a2c0
Autor:
Callum Dargavel, David Kevans, Mark S. Silverberg, Richard Kirsch, Boyko Kabakchiev, Robert H. Riddell
Publikováno v:
Inflamm Bowel Dis
Background In ulcerative colitis (UC) patients who have achieved mucosal healing, active microscopic colonic mucosal inflammation is commonly observed. We aimed to assess the association between histological activity and disease relapse in endoscopic
Autor:
Gilaad G. Kaplan, Sarah O’Donnell, A. Hillary Steinhart, Bertus Eksteen, Boyko Kabakchiev, Krzysztof Borowski, Joanne M. Stempak, Mark S. Silverberg, Dermot P.B. McGovern, Raquel Milgrom, Osvaldo Espin-Garcia, Deepah Panikkath, Wei Xu
Publikováno v:
Inflammatory Bowel Diseases. 25:1541-1549
Background While progress has been made in the identification of Crohn’s disease (CD) susceptibility loci, efforts to identify a genetic basis for disease progression have been less fruitful. The specific aim of this study was to build upon the maj
Autor:
Boyko Kabakchiev, Christina Mitropoulou, Veronika Litinski, Sara L Rogers, George P. Patrinos
Publikováno v:
Pharmacogenomics. 21(11)
The incorporation of personalized medicine interventions into routine healthcare constitutes an opportunity to improve patients' quality of life, as it empowers implementation of innovative, individualized clinical interventions that maximize efficac
Autor:
Melissa Filice, Michelle I. Smith, Aylia Mohammadi, Orlaith B Kelly, Boyko Kabakchiev, Mark S. Silverberg
Publikováno v:
Journal of Crohn's and Colitis. 12:568-581
BACKGROUND AND AIMS: MicroRNAs [miRNAs] have emerged as important regulators in inflammatory bowel disease [IBD]. This study investigated differential expression of miRNAs across clinical phenotypes in a well-characterized cohort of IBD patients and
Publikováno v:
Journal of the Canadian Association of Gastroenterology. 2:214-216
BACKGROUND: Approximately up to 30–60% of ulcerative colitis (UC) patients fail to infliximab (IFX) in real-life retrospective studies. Studies investigating early markers of poor clinical outcomes in UC patients starting IFX remain limited. AIMS:
Publikováno v:
Journal of the American Medical Directors Association. 21(6)
Objectives Assess the potential benefits of identifying drug-gene interactions in nursing home (NH) residents on multiple medications. Reduce the use of high-risk medications for residents with reduced drug metabolism. Design Open-label, nonrandomize
Autor:
Boyko Kabakchiev, Joanne M. Stempak, Larbi Bedrani, Kenneth Croitoru, Michelle I. Smith, K Boland, Williams Turpin, Krzysztof Borowski, G C Nguyen, Mark S. Silverberg, C A Hernandez Rocha, Hillary Steinhart
BACKGROUND: Pathogenesis of inflammatory bowel disease (IBD) is influenced by differences in the function of gut microbiota. Bile acid (BA) metabolism is carried out in the gastrointestinal tract mainly by three bacterial enzymes. These include a bil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c87c44cb2523f384215f16196134563
https://europepmc.org/articles/PMC6512249/
https://europepmc.org/articles/PMC6512249/