Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Boying Guo"'
Autor:
Hayley M. McDaid, Nancy R. Zhang, Andrea E. Prota, Alicia Rodriguez-Gabin, Tobias Mühlethaler, Michel O. Steinmetz, Kenny Ye, Amos B. Smith, Boying Guo, Susan Band Horwitz
Publikováno v:
Mol Pharmacol
The natural product (+)-discodermolide (DDM) is a microtubule stabilizing agent and potent inducer of senescence. We refined the structure of DDM and evaluated the activity of novel congeners in triple negative breast and ovarian cancers, malignancie
Publikováno v:
Organic Chemistry Frontiers. 7:3935-3940
3-Selenyl/sulfenyl chromones/thiochromones were conveniently synthesized from the PIFA-mediated reactions between alkynyl aryl ketones bearing an ortho-methoxy/methylthio group and diorganyl diselenides/disulfides. This metal-free approach is postula
Publikováno v:
Chemical communications (Cambridge, England). 56(91)
Hypervalent iodine reagents have been extensively employed in various types of oxidative organic reactions including oxidative coupling/cyclization, bifunctionalization of olefins and cyclopropane, C-H functionalization, and oxidative rearrangement r
Publikováno v:
Angewandte Chemie International Edition. 51:5675-5678
A variety of 2-vinyloxetanes smoothly undergoes Cu-catalyzed ring expansion to afford dihydropyran derivatives in high yields.
Publikováno v:
Tetrahedron Letters. 55:3232-3234
Presented in this Letter is a mild new method to stereoselectively ring open 1,1-disubstituted vinyl oxiranes using dialkyl dithiophosphate nucleophiles. This new reaction proceeds in toluene at room temperature to afford tri- and tetrasubstituted al
Publikováno v:
ChemInform. 45
In case of 1,1-disubstituted substrates (I) the nucleophile adds exclusively at the terminal carbon to give predominantely Z-products (III).
Autor:
Boying Guo, Jon T. Njardarson
Publikováno v:
ChemInform. 45
A mild vinyl oxetane (I) ring opening that affords mainly Z-substituted allylic thiophosphate products (III) in high yields is described.
Publikováno v:
ChemInform. 43
Unsaturated cyclic ethers can be mildly and selectively reduced with catalytic amounts of B(C6F5)3 in the presence of an alkylsilane. The allylic position is preferentially reduced with minimal or no scrambling of olefin geometry. For electronically
Publikováno v:
ChemInform. 43
A variety of 2-vinyloxetanes smoothly undergoes Cu-catalyzed ring expansion to afford dihydropyran derivatives in high yields.
Publikováno v:
Chemical communications (Cambridge, England). 48(63)
Unsaturated cyclic ethers can be mildly and selectively reduced with catalytic amounts of B(C(6)F(5))(3) in the presence of an alkylsilane. The allylic position is preferentially reduced with minimal or no scrambling of olefin geometry. For electroni