Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Boying Gong"'
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-29 (2024)
Abstract Increasingly, scRNA-Seq studies explore cell populations across different samples and the effect of sample heterogeneity on organism’s phenotype. However, relatively few bioinformatic methods have been developed which adequately address th
Externí odkaz:
https://doaj.org/article/63f57038731f451190d9327b3cc02021
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-21 (2021)
Abstract A growing number of single-cell sequencing platforms enable joint profiling of multiple omics from the same cells. We present Cobolt, a novel method that not only allows for analyzing the data from joint-modality platforms, but provides a co
Externí odkaz:
https://doaj.org/article/bec4cdb797634ac9b42a80cb5da8302d
Single-cell measurements of different cellular features or modalities from cells from the same system allow for a comprehensive understanding of a biological process. While the most common single-cell sequencing technologies require separate input ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::811e8e972952dce2fd971e9c2c4304b1
https://doi.org/10.1101/2021.04.03.438329
https://doi.org/10.1101/2021.04.03.438329
Publikováno v:
ACS biomaterials scienceengineering. 6(5)
Understanding the complex interplay of factors affecting nanoparticle accumulation in solid tumors is a challenge that must be surmounted to develop effective cancer nanomedicine. Among other unique microenvironment properties, tumor vascular permeab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::294505d5d58f293201ae1f169f7ecb3d
https://pubmed.ncbi.nlm.nih.gov/33463250
https://pubmed.ncbi.nlm.nih.gov/33463250
Autor:
Elizabeth Purdom, Boying Gong
Publikováno v:
Journal of computational biology : a journal of computational molecular cell biology. 27(4)
Whole-genome bisulfite sequencing (WGBS) provides a precise measure of methylation across the genome, yet presents a challenge in identifying regions that are differentially methylated (DMRs) between different conditions. A number of methods have bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9526c143cebfa3161a71149919e43a8
https://pubmed.ncbi.nlm.nih.gov/32176529
https://pubmed.ncbi.nlm.nih.gov/32176529
Understanding the complex interplay of factors affecting nanoparticle accumulation in solid tumors is a challenge that must be surmounted to develop effective cancer nanomedicine. The tumor microenvironment is unique in comparison to healthy tissue,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4931e3656bcfe9b6b5259844b0c8e99b
https://doi.org/10.1101/708263
https://doi.org/10.1101/708263
Autor:
Sandrine Dudoit, Rebecca K. Chance, Elizabeth Purdom, Darren W. Logan, Iain C. Macaulay, Boying Gong, Ralph Abi Hachem, Koen Van den Berge, Jonathan Mill, Hiroaki Matsunami, Tatsuya Tsukahara, Diya Das, Hector Roux de Bézieux, Davide Risso, Hsin-jung Chou, Caleb Weinreb, Russell B. Fletcher, Matthew S. Grubb, John Ngai, David H. Brann, Marcela Lipovsek, Sandeep Robert Datta, Bradley J. Goldstein, Kelly Street, Yoon Gi Choi
Publikováno v:
Science Advances
Brann, D H, Tsukahara, T, Weinreb, C, Lipovsek, M, Van den Berge, K, Gong, B, Chance, R, Macaulay, I C, Chou, H J, Fletcher, R B, Das, D, Street, K, de Bezieux, H R, Choi, Y G, Risso, D, Dudoit, S, Purdom, E, Mill, J, Hachem, R A, Matsunami, H, Logan, D W, Goldstein, B J, Grubb, M S, Ngai, J & Datta, S R 2020, ' Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia ', Science Advances, vol. 6, no. 31, abc5801 . https://doi.org/10.1126/sciadv.abc5801
SCIENCE ADVANCES
Brann, D H, Tsukahara, T, Weinreb, C, Lipovsek, M, Van den Berge, K, Gong, B, Chance, R, Macaulay, I C, Chou, H J, Fletcher, R B, Das, D, Street, K, de Bezieux, H R, Choi, Y G, Risso, D, Dudoit, S, Purdom, E, Mill, J, Hachem, R A, Matsunami, H, Logan, D W, Goldstein, B J, Grubb, M S, Ngai, J & Datta, S R 2020, ' Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia ', Science Advances, vol. 6, no. 31, abc5801 . https://doi.org/10.1126/sciadv.abc5801
SCIENCE ADVANCES
Altered olfactory function is a common symptom of COVID-19, but its etiology is unknown. A key question is whether SARS-CoV-2 (CoV-2) – the causal agent in COVID-19 – affects olfaction directly, by infecting olfactory sensory neurons or their tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e48f44434e9f0bf086d17ddb9c51087