Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Boye Schnack, Nielsen"'
Autor:
Boye Schnack Nielsen, Natasha Helleberg Madsen, Jesper Larsen, Isabella Skandorff, Monika Gad, Kim Holmstrøm
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
3D cancer cell cultures have enabled new opportunities for replacing compound testing in experimental animals. However, most solid tumors are composed of multiple cell types, including fibroblasts. In this study we developed multicellular tumor heter
Externí odkaz:
https://doaj.org/article/ed34f1c7b90146b7bb62572bf29dc2c3
Autor:
Jaslin Pallikkunnath James, Boye Schnack Nielsen, Ib Jarle Christensen, Ebbe Langholz, Mikkel Malham, Tim Svenstrup Poulsen, Kim Holmstrøm, Lene Buhl Riis, Estrid Høgdall
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Differential diagnosis of inflammatory bowel disease (IBD) to Crohn’s disease (CD) or ulcerative colitis (UC) is crucial for treatment decision making. With the aim of generating a clinically applicable molecular-based tool to classify IBD
Externí odkaz:
https://doaj.org/article/d978c2381668411fa9631bc9104e9339
Autor:
Jaslin P James, Lene Buhl Riis, Rolf Søkilde, Mikkel Malham, Estrid Høgdall, Ebbe Langholz, Boye Schnack Nielsen
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0297353 (2024)
Numerous pathogenic processes are mediated by short noncoding RNAs (sncRNA). Twenty percent of inflammatory bowel disease (IBD) patients are labelled as IBD unclassified (IBDU) at disease onset. Most IBDU patients are reclassified as Crohn's disease
Externí odkaz:
https://doaj.org/article/27ca41d1db3243afacb9008a0e69d617
Autor:
Silvia Aldi, Ljubica Perisic Matic, Gregory Hamm, Daniëlle van Keulen, Dennie Tempel, Kim Holmstrøm, Agnieszka Szwajda, Boye Schnack Nielsen, Valur Emilsson, Rima Ait-Belkacem, Mariette Lengquist, Gabrielle Paulsson-Berne, Per Eriksson, Jan H.N. Lindeman, Alain J. Gool, Jonathan Stauber, Ulf Hedin, Eva Hurt-Camejo
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 10, Iss , Pp 17-28 (2018)
Variants in the PLPP3 gene encoding for lipid phosphate phosphohydrolase 3 have been associated with susceptibility to atherosclerosis independently of classical risk factors. PLPP3 inactivates lysophosphatidic acid (LPA), a pro-inflammatory, pro-thr
Externí odkaz:
https://doaj.org/article/7bfc8ac6211a4952996ab2d554be695f
Autor:
Natasha Helleberg Madsen, Boye Schnack Nielsen, Son Ly Nhat, Søren Skov, Monika Gad, Jesper Larsen
Publikováno v:
Pathogens, Vol 10, Iss 8, p 969 (2021)
Tumor-associated macrophages often correlate with tumor progression, and therapies targeting immune cells in tumors have emerged as promising treatments. To select effective therapies, we established an in vitro 3D multicellular spheroid model includ
Externí odkaz:
https://doaj.org/article/ee36167db7934cdb8077d64ccc16f1cf
Autor:
Saskia Altmaier, Ina Meiser, Emilie Lemesre, Benjamin Chanrion, Rachel Steeg, Lidia Elena Leonte, Bjørn Holst, Boye Schnack Nielsen, Christian Clausen, Katharina Schmidt, Anne Marie Vinggaard, Heiko Zimmermann, Julia Christiane Neubauer, Mikkel Aabech Rasmussen
Publikováno v:
Altmaier, S, Meiser, I, Lemesre, E, Chanrion, B, Steeg, R, Leonte, L E, Holst, B, Nielsen, B S, Clausen, C, Schmidt, K, Vinggaard, A M, Zimmermann, H, Neubauer, J C & Rasmussen, M A 2022, ' Human iPSC-derived hepatocytes in 2D and 3D suspension culture for cryopreservation and in vitro toxicity studies ', Reproductive Toxicology, vol. 111, pp. 68-80 . https://doi.org/10.1016/j.reprotox.2022.05.005
Reproductive Toxicology
Reproductive Toxicology
Hepatocytes are of special interest in biomedical research for disease modelling, drug screening and in vitro toxicology. Human induced pluripotent stem cell (hiPSC)-derived hepatocytes could complement primary human hepatocytes due to their capabili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6efbd504844b8218152ca3ecf4a43ddd
https://doi.org/10.1016/j.reprotox.2022.05.005
https://doi.org/10.1016/j.reprotox.2022.05.005
Autor:
Danielle van Keulen, Marianne G Pouwer, Valur Emilsson, Ljubica Perisic Matic, Elsbet J Pieterman, Ulf Hedin, Vilmundur Gudnason, Lori L Jennings, Kim Holmstrøm, Boye Schnack Nielsen, Gerard Pasterkamp, Jan H N Lindeman, Alain J van Gool, Maarten D Sollewijn Gelpke, Hans M G Princen, Dennie Tempel
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0221477 (2019)
ObjectivePrevious studies indicate a role for Oncostatin M (OSM) in atherosclerosis and other chronic inflammatory diseases for which inhibitory antibodies are in development. However, to date no intervention studies with OSM have been performed, and
Externí odkaz:
https://doaj.org/article/ca346d3188e04a0dac053e012ce18eb6
Autor:
Noona Ambartsumian, Eugene Lukanidin, Boye Schnack Nielsen, Kasper Almholt, Mariam Grigorian, Jörg Klingelhöfer, Birgitte Grum-Schwensen
Supplementary Materials, Table 1-2, Figure 1 from Lung Metastasis Fails in MMTV-PyMT Oncomice Lacking S100A4 Due to a T-Cell Deficiency in Primary Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::559947254249763abe9fd0dfd2834b33
https://doi.org/10.1158/0008-5472.22386908
https://doi.org/10.1158/0008-5472.22386908
Autor:
Jaslin P. James, Boye Schnack Nielsen, Ebbe Langholz, Mikkel Malham, Estrid Høgdall, Lene Buhl Riis
Tumour necrosis factor-α (TNF) antagonists have improved the management of inflammatory bowel disease (IBD), however, their usage and administration persist to be suboptimal. Here, we examined the relationship between tissue-specific TNF mRNA expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2227275feb355ff5af59cbeb5ee6295
Autor:
Kirsten Nguyen Knudsen, Jan Lindebjerg, Boye Schnack Nielsen, Torben Frøstrup Hansen, Flemming Brandt Sørensen
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0178564 (2017)
The microRNA-200 (miR-200) family acts as a major suppressor of epithelial-mesenchymal transition (EMT). Impaired miR-200 expression may lead to EMT initiation and eventually cancer dissemination. The presence of tumor budding cells (TBC) is associat
Externí odkaz:
https://doaj.org/article/b7819da670174e4680ff05a72e2bca56