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Quelle que soit la voie de dépôt, l'acide aminé 31 dans le variant d'histone H3 est essentiel à la gastrulation chez Xenopus

Autor: Sitbon, David, Boyarchuk, Ekaterina, Almouzni, Geneviève

The closely related replicative H3 and non-replicative H3.3 variants show specific requirement during development in vertebrates. Whether it involves distinct mode of deposition or unique roles once incorporated into chromatin remains unclear. To dis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______212::5b29cfe6718538f806c937268aaa35fe
https://hal.archives-ouvertes.fr/hal-03041039

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Metabolic Deregulations Affecting Chromatin Architecture: One-Carbon Metabolism and Krebs Cycle Impact Histone Methylation

Autor: Saavedra, Francisco, Boyarchuk, Ekaterina, Alvarez, Francisca, Almouzni, Geneviève, Loyola, Alejandra

Publikováno v: The DNA,RNA, and Histone Methylomes. RNA Technologies.
The DNA,RNA, and Histone Methylomes. RNA Technologies., pp.573-606, 2019, 978-3-030-14791-4. ⟨10.1007/978-3-030-14792-1_23⟩
The DNA,RNA, and Histone Methylomes. RNA Technologies., RNATECHN, pp.573-606, 2019, 978-3-030-14791-4. ⟨10.1007/978-3-030-14792-1_23⟩

The methylation status of a particular amino acid results from the interplay of two enzymes: “Writers” (methyltransferases) and “Erasers” (demethylases). Methylation of histones in chromatin can be recognized by “Readers” which induce cha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6e8693e7221a85f710169a1595a9a61e
https://hal.archives-ouvertes.fr/hal-02371144

L'activité fonctionnelle du complexe d'histone chaperon H3.3 HIRA nécessite la trimérisation de la sous-unité HIRA

Autor: Ray-Gallet, Dominique, Ricketts, M. Daniel, Sato, Yukari, Gupta, Kushol, Boyarchuk, Ekaterina, Senda, Toshiya, Marmorstein, Ronen, Almouzni, Geneviève

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.3103 article number. ⟨10.1038/s41467-018-05581-y⟩

International audience; The HIRA histone chaperone complex deposits the histone variant H3.3 onto chromatin in a DNA synthesis-independent manner. It comprises three identified subunits, HIRA, UBN1 and CABIN1, however the functional oligomerization s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______212::44badad729f60ebc1a8c8383993e1300
https://hal.archives-ouvertes.fr/hal-02370978/document