Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Boxue He"'
Autor:
Guangxue Liu, Jimin Li, Boxue He, Jiaqi Yan, Jingyu Zhao, Xuejie Wang, Xiaocong Zhao, Jingyan Xu, Yeyao Wu, Simin Zhang, Xiaoli Gan, Chun Zhou, Xiangpan Li, Xinghua Zhang, Xuefeng Chen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Central to homologous recombination (HR) is the assembly of Rad51 recombinase on single-strand DNA (ssDNA), forming the Rad51-ssDNA filament. How the Rad51 filament is efficiently established and sustained remains partially understood. Here,
Externí odkaz:
https://doaj.org/article/04980784b62f49d0922059cc06095766
Autor:
Anne Olazabal-Herrero, Boxue He, Youngho Kwon, Abhishek K. Gupta, Arijit Dutta, Yuxin Huang, Prajwal Boddu, Zhuobin Liang, Fengshan Liang, Yaqun Teng, Li Lan, Xiaoyong Chen, Huadong Pei, Manoj M. Pillai, Patrick Sung, Gary M. Kupfer
Publikováno v:
Cell Reports, Vol 43, Iss 1, Pp 113610- (2024)
Summary: Fanconi anemia (FA) is characterized by congenital abnormalities, bone marrow failure, and cancer susceptibility. The central FA protein complex FANCI/FANCD2 (ID2) is activated by monoubiquitination and recruits DNA repair proteins for inter
Externí odkaz:
https://doaj.org/article/bc92b447e5014f469f04a528e03fd245
Autor:
Rui Yang, Weilin Peng, Shuai Shi, Xiong Peng, Qidong Cai, Zhenyu Zhao, Boxue He, Guangxu Tu, Wei Yin, Yichuan Chen, Yuqian Zhang, Fang Liu, Xiang Wang, Desheng Xiao, Yongguang Tao
Publikováno v:
Advanced Science, Vol 10, Iss 25, Pp n/a-n/a (2023)
Abstract Accumulation of vimentin is the core event in epithelial–mesenchymal transition (EMT). Post‐translational modifications have been widely reported to play crucial roles in imparting different properties and functions to vimentin. Here, a
Externí odkaz:
https://doaj.org/article/ebd0325fda0947178fc01287cda98d5c
Autor:
Jodie D. Cropper, Dauren S. Alimbetov, Kevin T. G. Brown, Rostislav I. Likhotvorik, Andrew J. Robles, James T. Guerra, Boxue He, Yidong Chen, Youngho Kwon, Raushan T. Kurmasheva
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-6 (2022)
Abstract DNA lesions induced by alkylating agents are repaired by two canonical mechanisms, base excision repair dependent on poly(ADP) ribose polymerase 1 (PARP1) and the other mediated by O6-methylguanine (O6meG)-DNA methyltransferase (MGMT) in a s
Externí odkaz:
https://doaj.org/article/5b3757c443a5481e8a6488e272f662ca
Autor:
Qidong Cai, Boxue He, Guangxu Tu, Weilin Peng, Shuai Shi, Banglun Qian, Qingchun Liang, Shaoliang Peng, Yongguang Tao, Xiang Wang
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107013- (2023)
Summary: Exploring early detection methods through comprehensive evaluation of DNA methylation for lung squamous cell carcinoma (LUSC) patients is of great significance. By using different machine learning algorithms for feature selection and model c
Externí odkaz:
https://doaj.org/article/ddccc37119014aa78afbdb28f3ace74e
Autor:
Boxue He, Cong Wei, Qidong Cai, Pengfei Zhang, Shuai Shi, Xiong Peng, Zhenyu Zhao, Wei Yin, Guangxu Tu, Weilin Peng, Yongguang Tao, Xiang Wang
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-16 (2022)
Abstract Background Alternative splicing (AS) plays important roles in transcriptome and proteome diversity. Its dysregulation has a close affiliation with oncogenic processes. This study aimed to evaluate AS-based biomarkers by machine learning algo
Externí odkaz:
https://doaj.org/article/fa352d6fd9a04138ab5ca2eef9b9218d
Autor:
Xiong Peng, Rui Yang, Weilin Peng, Zhenyu Zhao, Guangxu Tu, Boxue He, Qidong Cai, Shuai Shi, Wei Yin, Fenglei Yu, Yongguang Tao, Xiang Wang
Publikováno v:
PeerJ, Vol 10, p e14180 (2022)
According to mounting evidence, long noncoding RNAs (lncRNAs) play a vital role in regulated cell death (RCD). A potential strategy for cancer therapy involves triggering ferroptosis, a novel form of RCD. Although it is thought to be an autophagy-dep
Externí odkaz:
https://doaj.org/article/a6b93aafde6841b98c9c8ace246fc7d3
Autor:
Zhenyu Zhao, Wei Yin, Xiong Peng, Qidong Cai, Boxue He, Shuai Shi, Weilin Peng, Guangxu Tu, Yunping Li, Dateng Li, Yongguang Tao, Muyun Peng, Xiang Wang, Fenglei Yu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Screening for early-stage lung cancer with low-dose computed tomography is recommended for high-risk populations; consequently, the incidence of pure ground-glass opacity (pGGO) is increasing. Ground-glass opacity (GGO) is considered the appearance o
Externí odkaz:
https://doaj.org/article/2ccd6d10ec35421dac075298e3b6e39f
Autor:
Qidong Cai, Boxue He, Pengfei Zhang, Zhenyu Zhao, Xiong Peng, Yuqian Zhang, Hui Xie, Xiang Wang
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-15 (2020)
Abstract Background Alternative splicing (AS) plays critical roles in generating protein diversity and complexity. Dysregulation of AS underlies the initiation and progression of tumors. Machine learning approaches have emerged as efficient tools to
Externí odkaz:
https://doaj.org/article/29a314920dba4008a0a4865dc55a70a8
Autor:
Qidong Cai, Boxue He, Hui Xie, Pengfei Zhang, Xiong Peng, Yuqian Zhang, Zhenyu Zhao, Xiang Wang
Publikováno v:
Cancer Medicine, Vol 9, Iss 20, Pp 7488-7502 (2020)
Abstract Abnormal DNA methylation persists throughout carcinogenesis and cancer development. Hence, gene promoter methylation may act as a prognostic tool and provide new potential therapeutic targets for patients with lung adenocarcinoma (LUAD). In
Externí odkaz:
https://doaj.org/article/1e6c32f9ba3543fc96202d94a4f15d87