Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Boxuan Simen, Zhao"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/9febef2b58a5425e8994fea2f9b2015f
Autor:
Miaoge Xue, Boxuan Simen Zhao, Zijie Zhang, Mijia Lu, Olivia Harder, Phylip Chen, Zhike Lu, Anzhong Li, Yuanmei Ma, Yunsheng Xu, Xueya Liang, Jiyong Zhou, Stefan Niewiesk, Mark E. Peeples, Chuan He, Jianrong Li
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
Here, Xue et al. identify N 6-methyladenosine (m6A) modification sites in RNAs of respiratory syncytial virus (RSV) and show that these sites, particularly sites in the transcript encoding for the viral glycoprotein, affect virus replication in prima
Externí odkaz:
https://doaj.org/article/ae5353928f864471a17a92fe4c1248b7
Publikováno v:
Scientific Reports, Vol 6, Iss 1, Pp 1-6 (2016)
Abstract 5-hydroxymethylcytosine (5 hmC), the oxidized form of 5-methylcytosine (5 mC), is a base modification with emerging importance in biology and disease. However, like most epigenetic elements, it is transparent to many conventional genetic tec
Externí odkaz:
https://doaj.org/article/ea941c6ded3640d690aca9ec52d7c1d4
Publikováno v:
eLife, Vol 6 (2017)
Externí odkaz:
https://doaj.org/article/e356796a9c05468bb1e1f7a515ad2ea2
Publikováno v:
eLife, Vol 5 (2016)
The internal N6-methyladenosine (m6A) methylation of eukaryotic nuclear RNA controls post-transcriptional gene expression, which is regulated by methyltransferases (writers), demethylases (erasers), and m6A-binding proteins (readers) in cells. The YT
Externí odkaz:
https://doaj.org/article/38e9dc88f0df4d63b77090738ee2271b
Publikováno v:
Proc Natl Acad Sci U S A
RNA–protein interactions underlie a wide range of cellular processes. Improved methods are needed to systematically map RNA–protein interactions in living cells in an unbiased manner. We used two approaches to target the engineered peroxidase APE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2cd41f019174ed1c8072814e4302f9e
https://doi.org/10.1073/pnas.2006617117
https://doi.org/10.1073/pnas.2006617117
Autor:
Yunsheng Xu, Chuan He, Mark E. Peeples, Olivia Harder, Xueya Liang, Boxuan Simen Zhao, Jianrong Li, Zongdi Feng, Miaoge Xue, Jiyong Zhou, Mijia Lu, Thomas Z. Gao, Zijie Zhang, Stefan Niewiesk, Anzhong Li
Publikováno v:
Nature Microbiology. 5:584-598
Internal N6-methyladenosine (m6A) modification is one of the most common and abundant modifications of RNA. However, the biological roles of viral RNA m6A remain elusive. Here, using human metapneumovirus (HMPV) as a model, we demonstrate that m6A se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90a175d9a1d676a710a0aa97f28ece31
https://doi.org/10.1038/s41564-019-0653-9
https://doi.org/10.1038/s41564-019-0653-9
Autor:
Minjie Wei, Zhenhua Chen, Huilin Huang, Jun Liu, Ke-Ren Zhou, Markus Müschen, Juan Du, Xi Jiang, Shu Tao, Chenying Li, Mingli Sun, Hang Yin, Jianjun Chen, Xiwei Wu, Gang Xiao, Yueh-Chiang Hu, Xi Qin, Franziska Auer, Ying Qing, Jian-Hua Yang, Celvie L. Yuan, Jun-Lin Guan, Lei Dong, Chao Shen, Hanjun Qin, Chuan He, Gang Huang, Boxuan Simen Zhao, Huizhe Wu, Hengyou Weng, Wen-Ju Sun, Yunzhu Dong, Yile Zhou, Liang-Hu Qu, Zhike Lu, Rui Su, Lars Klemm, Zhixiang Zuo, Miao Sun, Xiaolan Deng, Tong Wu, Ana Mesquita
Publikováno v:
Nature. 567:414-419
DNA and histone modifications have notable effects on gene expression1. Being the most prevalent internal modification in mRNA, the N6-methyladenosine (m6A) mRNA modification is as an important post-transcriptional mechanism of gene regulation2–4 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec9971bb9405907554d87e9df7e2574c
https://doi.org/10.1038/s41586-019-1016-7
https://doi.org/10.1038/s41586-019-1016-7
RNA-protein interactions underlie a wide range of cellular processes. Improved methods are needed to systematically map RNA-protein interactions in living cells in an unbiased manner. Capitalizing on the ability of the engineered peroxidase APEX2 to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bcf956c5868c70d24d08fc5038e0202
Autor:
Ana Mesquita, Hailing Shi, Wen-Ju Sun, Stefan Hüttelmaier, Xi Jiang, Huilin Huang, Minjie Wei, Boxuan Simen Zhao, Jianjun Chen, Lei Dong, Yungui Wang, Xi Qin, Yueh-Chiang Hu, Sigrid Nachtergaele, Miao Sun, Kenneth D. Greis, Chang Liu, Kyle Ferchen, Rui Su, Jennifer R. Skibbe, Celvie L. Yuan, Huizhe Wu, Liang-Hu Qu, Xiaolan Deng, Chuan He, Chao Hu, Jian-Hua Yang, Jun-Lin Guan, Chenying Li, Hengyou Weng
Publikováno v:
Nature cell biology
N6-methyladenosine (m6A) is the most prevalent modification in eukaryotic messenger RNAs (mRNAs) and is interpreted by its readers, such as YTH domain-containing proteins, to regulate mRNA fate. Here, we report the insulin-like growth factor 2 mRNA-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca65e7e08bbb21521ab9f96800ebca04
http://europepmc.org/articles/PMC5826585
http://europepmc.org/articles/PMC5826585