Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Bowyer, G."'
Autor:
Sharpe, H. R.1 (AUTHOR) hannah.sharpe@msdtc.ox.ac.uk, Bowyer, G.1 (AUTHOR), Brackenridge, S.2 (AUTHOR), Lambe, T.1 (AUTHOR) teresa.lambe@ndm.ox.ac.uk
Publikováno v:
Clinical & Experimental Immunology. May2019, Vol. 196 Issue 2, p167-177. 11p. 1 Diagram, 3 Charts.
Autor:
Jones, N. K., Rivett, L., Sparkes, D., Forrest, S., Sridhar, S., Young, J., Pereira-Dias, J., Cormie, C., Gill, H., Reynolds, N., Wantoch, M., Routledge, M., Warne, B., Levy, J., Jimenez, W. D. C., Samad, F. N. B., Mcnicholas, C., Ferris, M., Gray, J., Gill, M., Curran, M. D., Fuller, S., Chaudhry, A., Shaw, A., Bradley, J. R., Hannon, G. J., Goodfellow, I. G., Dougan, G., Smith, K. G. C., Lehner, P. J., Wright, G., Matheson, N. J., Baker, S., Weekes, M. P., Bradley, J., Goodfellow, I., Gupta, R., Lyons, P. A., Torok, M. E., Toshner, M., Kean, I., Caddy, S., Caller, L., Feltwell, T., Hall, G., Hamilton, W., Hosmillo, M., Houldcroft, C., Jahun, A., Khokhar, F., Meredith, L., Yakovleva, A., Butcher, H., Caputo, D., Clapham-Riley, D., Dolling, H., Furlong, A., Graves, B., Gresley, E. L., Kingston, N., Papadia, S., Stark, H., Stirrups, K. E., Webster, J., Calder, J., Harris, J., Hewitt, S., Kennet, J., Meadows, A., Rastall, R., Brien, C. O., Price, J., Publico, C., Rowlands, J., Ruffolo, V., Tordesillas, H., Hannon, G., Brookes, K., Canna, L., Cruz, I., Dempsey, K., Elmer, A., Escoffery, N., Jones, H., Ribeiro, C., Saunders, C., Wright, A., Nyagumbo, R., Roberts, A., Bucke, A., Hargreaves, S., Johnson, D., Narcorda, A., Read, D., Sparke, C., Worboys, L., Lagadu, K., Mactavous, L., Gould, T., Raine, T., Mather, C., Ramenatte, N., Vallier, A. -L., Kasanicki, M., Eames, P. -J., Thake, L., Bartholomew, N., Brown, N., Curran, M., Parmar, S., Zhang, H., Bowring, A., Martell, G., Quinnell, N., Wright, J., Murphy, H., Dunmore, B. J., Legchenko, E., Graf, S., Huang, C., Hodgson, J., Hunter, K., Martin, J., Mescia, F., Odonnell, C., Pointon, L., Shih, J., Sutcliffe, R., Tilly, T., Tong, Z., Treacy, C., Wood, J., Bergamaschi, L., Betancourt, A., Bowyer, G., De Sa, A., Epping, M., Hinch, A., Huhn, O., Jarvis, I., Lewis, D., Marsden, J., Mccallum, S., Nice, F., Omarjee, O., Perera, M., Romashova, N., Strezlecki, M., Yarkoni, N. S., Turner, L., Bailey, B., Doughton, R., Workman, C., Trotter, C., David, W., Jimenez, C.
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Previously, we showed that 3% (31/1032)of asymptomatic healthcare workers (HCWs) from a large teaching hospital in Cambridge, UK, tested positive for SARS-CoV-2 in April 2020. About 15% (26/169) HCWs with symptoms of coronavirus disease 2019 (COVID-1
Cytomegalovirus (CMV) is associated with immunosenescence and reduced vaccine responses in the elderly (>70 years). However, the impact of CMV in young adults is less clear. In this study, healthy UK and Senegalese adults aged 18-50 years (average 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::e009ce28f983108f81e04889f4f1b579
https://doi.org/10.1084/jem.20200004
https://doi.org/10.1084/jem.20200004
Autor:
Rivett, L., Sridhar, S., Sparkes, D., Routledge, M., Jones, N. K., Forrest, S., Young, J., Pereira-Dias, J., Hamilton, W. L., Ferris, M., Torok, M. E., Meredith, L., Curran, M. D., Fuller, S., Chaudhry, A., Shaw, A., Samworth, R. J., Bradley, J. R., Dougan, G., Smith, K. G. C., Lehner, P. J., Matheson, N. J., Wright, G., Goodfellow, I. G., Baker, S., Weekes, M. P., Lyons, P. A., Toshner, M., Warne, B., Scott, J. B., Cormie, C., Gill, H., Kean, I., Maes, M., Reynolds, N., Wantoch, M., Caddy, S., Caller, L., Feltwell, T., Hall, G., Hosmillo, M., Houldcroft, C., Jahun, A., Khokhar, F., Yakovleva, A., Butcher, H., Caputo, D., Clapham-Riley, D., Dolling, H., Furlong, A., Graves, B., Gresley, E. L., Kingston, N., Papadia, S., Stark, H., Stirrups, K. E., Webster, J., Calder, J., Harris, J., Hewitt, S., Kennet, J., Meadows, A., Rastall, R., Brien, C. O., Price, J., Publico, C., Rowlands, J., Ruffolo, V., Tordesillas, H., Brookes, K., Canna, L., Cruz, I., Dempsey, K., Elmer, A., Escoffery, N., Jones, H., Ribeiro, C., Saunders, C., Wright, A., Nyagumbo, R., Roberts, A., Bucke, A., Hargreaves, S., Johnson, D., Narcorda, A., Read, D., Sparke, C., Warboys, L., Lagadu, K., Mactavous, L., Gould, T., Raine, T., Mather, C., Ramenatte, N., Vallier, A. -L., Kasanicki, M., Eames, P. -J., Mcnicholas, C., Thake, L., Bartholomew, N., Brown, N., Parmar, S., Zhang, H., Bowring, A., Martell, G., Quinnell, N., Wright, J., Murphy, H., Dunmore, B. J., Legchenko, E., Graf, S., Huang, C., Hodgson, J., Hunter, K., Martin, J., Mescia, F., O'Donnell, C., Pointon, L., Shih, J., Sutcliffe, R., Tilly, T., Tong, Z., Treacy, C., Wood, J., Bergamaschi, L., Betancourt, A., Bowyer, G., A. D., Sa, Epping, M., Hinch, A., Huhn, O., Jarvis, I., Lewis, D., Marsden, J., Mccallum, S., Nice, F.
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Significant differences exist in the availability of healthcare worker (HCW) SARS-CoV-2 testing between countries, and existing programmes focus on screening symptomatic rather than asymptomatic staff. Over a 3 week period (April 2020), 1032 asymptom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dae70c049f86e291261c3b58a190544
http://hdl.handle.net/11379/562821
http://hdl.handle.net/11379/562821
Autor:
Bliss, CM, Drammeh, A, Bowyer, G, Sanou, GS, Jagne, YJ, Ouedraogo, O, Edwards, NJ, Tarama, C, Ouedraogo, N, Ouedraogo, M, Njie-Jobe, J, Diarra, A, Afolabi, MO, Tiono, AB, Yaro, JB, Adetifa, UJ, Hodgson, SH, Anagnostou, NA, Roberts, R, Duncan, CJA, Cortese, R, Viebig, NK, Leroy, O, Lawrie, AM, Flanagan, KL, Kampmann, B, Imoukhuede, EB, Sirima, SB, Bojang, K, Hill, AVS, Nebie, I, Ewer, KJ
Publikováno v:
Molecular Therapy
Heterologous prime-boosting with viral vectors encoding the pre-erythrocytic antigen thrombospondin-related adhesion protein fused to a multiple epitope string (ME-TRAP) induces CD8+ T cell-mediated immunity to malaria sporozoite challenge in Europea
Autor:
Bowyer, G
An efficacious malaria vaccine will be a necessary tool for malaria eradication, however current vaccine candidates have only demonstrated a moderate level of short-term efficacy. Additionally, these vaccines often display reduced immunogenicity and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::3081614a9fb7efeda38c912d2e6b9cea
https://ora.ox.ac.uk/objects/uuid:91ee68f3-2a16-4241-8cfe-1654bcdb2b1b
https://ora.ox.ac.uk/objects/uuid:91ee68f3-2a16-4241-8cfe-1654bcdb2b1b
Autor:
Venkatraman, N, Bowyer, G, Edwards, NJ, Griffiths, O, Powlson, J, Silman, D, Morter, R, Folegatti, PM, Minassian, AM, Poulton, ID, Collins, K, Brod, F, Angell-Manning, P, Berrie, E, Brendish, N, Glenn, G, Fries, L, Baum, J, Blagborough, AM, Roberts, R, Lawrie, AM, Lewis, DJ, Faust, SN, Gilbert, S, Ewer, KJ, Hill, AV
It remains a global health priority to develop a durable and highly efficacious malaria vaccine. The most advanced malaria vaccine candidate, RTS,S/AS01 has completed Phase III testing in a multicentre study across several African sites and demonstra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::cdeff7a19e2b23f37f8e072d98cfab76
https://ora.ox.ac.uk/objects/uuid:e433efac-8e80-4278-b303-3537df06b9f7
https://ora.ox.ac.uk/objects/uuid:e433efac-8e80-4278-b303-3537df06b9f7
Autor:
Rampling, T, Ewer, KJ, Bowyer, G, Edwards, NJ, Wright, D, Sridhar, S, Payne, R, Powlson, J, Bliss, C, Venkatraman, N, Poulton, ID, De Graaf, H, Gbesemete, D, Grobbelaar, A, Davies, H, Roberts, R, Angus, B, Ivinson, K, Weltzin, R, Rajkumar, B-Y, Wille-Reece, U, Lee, C, Ockenhouse, C, Sinden, R, Gerry, SC, Lawrie, A, Vekemans, J, Morelle, D, Lievens, M, Ballou, RW, Lewis, DJM, Cooke, GS, Faust, SN, Hill, AV
We assessed a combination multi-stage malaria vaccine schedule in which RTS,S/AS01B was given concomitantly with viral vectors expressing multiple-epitope thrombospondin-related adhesion protein (ME-TRAP) in a 0-month, 1-month, and 2-month schedule.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1032::dc212b786e31c4ff489f1ace7a3a24bc
http://hdl.handle.net/10044/1/64182
http://hdl.handle.net/10044/1/64182
Autor:
Ewer (nee Russell), K, Bowyer, G, Grobbelaar, A, Rampling, T, Venkatraman, N, Morelle, D, Ballou, R, Hill, A
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology
Frontiers in Immunology
A malaria vaccine strategy targeting multiple lifecycle stages may be required to achieve a high level of efficacy. In two Phase IIa clinical trials, we tested immunogenicity and efficacy of RTS,S/AS01B administered alone, in a staggered regimen with
Autor:
Tiono, AB, Ouedraogo, A, Coulibaly, SA, Bougouma, EC, Ouedraogo, IN, Navin, V, Bowyer, G, Ewer, K, Viebig, N, Diarra, A, Glenn, G, Leroy, O, Hill, AV, Sirima, SB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::462698e4ae7b417879334550a48ea7b3
https://ora.ox.ac.uk/objects/uuid:d75749e3-63f5-4ada-9877-29f72e5a2280
https://ora.ox.ac.uk/objects/uuid:d75749e3-63f5-4ada-9877-29f72e5a2280