Characterisation of huntingtin localisation and transcriptional regulation in response to growth factor stimulation in an immortalised cell model of Huntington's Disease

Autor: Bowles, Kathryn R.

Disease (HD) is an autosomal dominant neurodegenerative disease caused by a CAG expansion on the HD gene on chromosome 4, which gives rise to an expanded polyglutamine (polyQ) tract in the huntingtin protein. HD is characterised primarily by motor ab

Externí odkaz: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.590321

17q21.31 sub-haplotypes underlying H1-associated risk for Parkinson's disease are associated with LRRC37A/2 expression in astrocytes.

Autor: Bowles, Kathryn R.^1,2 (AUTHOR), Pugh, Derian A.^1,2 (AUTHOR), Liu, Yiyuan^1,2 (AUTHOR), Patel, Tulsi^1,2 (AUTHOR), Renton, Alan E.^1,2 (AUTHOR), Bandres-Ciga, Sara³ (AUTHOR), Gan-Or, Ziv^4,5,6 (AUTHOR), Heutink, Peter^7,8 (AUTHOR), Siitonen, Ari^9,10 (AUTHOR), Bertelsen, Sarah^1,2 (AUTHOR), Cherry, Jonathan D.^11,12,13,14 (AUTHOR), Karch, Celeste M.¹⁵ (AUTHOR), Frucht, Steven J.¹⁶ (AUTHOR), Kopell, Brian H.^17,18 (AUTHOR), Peter, Inga^19,20 (AUTHOR), Park, Y. J.^17,21 (AUTHOR), Charney, Alexander^1,17,19,21 (AUTHOR), Raj, Towfique^1,2,19,22 (AUTHOR), Crary, John F.^1,2,23 (AUTHOR), Goate, A. M.^1,2,19,22 (AUTHOR) alison.goate@mssm.edu

Publikováno v: Molecular Neurodegeneration. 7/15/2022, Vol. 17 Issue 1, p1-21. 21p.

Additional file 5 of 17q21.31 sub-haplotypes underlying H1-associated risk for Parkinson’s disease are associated with LRRC37A/2 expression in astrocytes

Autor: Bowles, Kathryn R., Pugh, Derian A., Liu, Yiyuan, Patel, Tulsi, Renton, Alan E., Bandres-Ciga, Sara, Gan-Or, Ziv, Heutink, Peter, Siitonen, Ari, Bertelsen, Sarah, Cherry, Jonathan D., Karch, Celeste M., Frucht, Steven J., Kopell, Brian H., Peter, Inga, Park, Y. J., Charney, Alexander, Raj, Towfique, Crary, John F., Goate, A. M.

Additional file 5. Supplementary fig 5

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e2a7cacec84e4c92c8e22887bea0ad0

Additional file 10 of 17q21.31 sub-haplotypes underlying H1-associated risk for Parkinson’s disease are associated with LRRC37A/2 expression in astrocytes

Autor: Bowles, Kathryn R., Pugh, Derian A., Liu, Yiyuan, Patel, Tulsi, Renton, Alan E., Bandres-Ciga, Sara, Gan-Or, Ziv, Heutink, Peter, Siitonen, Ari, Bertelsen, Sarah, Cherry, Jonathan D., Karch, Celeste M., Frucht, Steven J., Kopell, Brian H., Peter, Inga, Park, Y. J., Charney, Alexander, Raj, Towfique, Crary, John F., Goate, A. M.

Additional file 10. Supplementary table 3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d02d13883a69a03b916df75571597f1

Additional file 7 of 17q21.31 sub-haplotypes underlying H1-associated risk for Parkinson’s disease are associated with LRRC37A/2 expression in astrocytes

Autor: Bowles, Kathryn R., Pugh, Derian A., Liu, Yiyuan, Patel, Tulsi, Renton, Alan E., Bandres-Ciga, Sara, Gan-Or, Ziv, Heutink, Peter, Siitonen, Ari, Bertelsen, Sarah, Cherry, Jonathan D., Karch, Celeste M., Frucht, Steven J., Kopell, Brian H., Peter, Inga, Park, Y. J., Charney, Alexander, Raj, Towfique, Crary, John F., Goate, A. M.

Additional file 7. Supplementary fig 7

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9900a4efd357d31b104a886918c0222a