Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Bowie Yik‐Ling Cheng"'
Autor:
Bai‐Liang He, Ning Yang, Cheuk Him Man, Nelson Ka‐Lam Ng, Chae‐Yin Cher, Ho‐Ching Leung, Leo Lai‐Hok Kan, Bowie Yik‐Ling Cheng, Stephen Sze‐Yuen Lam, Michelle Lu‐Lu Wang, Chun‐Xiao Zhang, Hin Kwok, Grace Cheng, Rakesh Sharma, Alvin Chun‐Hang Ma, Chi‐Wai Eric So, Yok‐Lam Kwong, Anskar Yu‐Hung Leung
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 4, Pp 1-19 (2020)
Abstract Internal tandem duplication of Fms‐like tyrosine kinase 3 (FLT3/ITD) occurs in about 30% of acute myeloid leukemia (AML) and is associated with poor response to conventional treatment and adverse outcome. Here, we reported that human FLT3/
Externí odkaz:
https://doaj.org/article/7425c255c2b944118072f12994ea5710
Autor:
Dandan Wang, Lichuan Zheng, Bowie Yik Ling Cheng, Chun-Fung Sin, Runsheng Li, Sze Pui Tsui, Xinyu Yi, Alvin Chun Hang Ma, Bai Liang He, Anskar Yu Hung Leung, Xuan Sun
Publikováno v:
Oncogene. 42:1272-1281
Isocitrate dehydrogenase 2 (IDH2) mutations occur in more than 15% of cytogenetically normal acute myeloid leukemia (CN-AML) but comparative studies of their roles in leukemogenesis have been scarce. We generated zebrafish models of IDH2R172K and IDH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3775e1979ee1fe4837d89eb5baea40f3
https://doi.org/10.1038/s41388-023-02611-y
https://doi.org/10.1038/s41388-023-02611-y
Autor:
Eunice Yuen Ting Lau, Jessica Lo, Bowie Yik Ling Cheng, Mark Kin Fai Ma, Joyce Man Fong Lee, Johnson Kai Yu Ng, Stella Chai, Chi Ho Lin, Suk Ying Tsang, Stephanie Ma, Irene Oi Lin Ng, Terence Kin Wah Lee
Publikováno v:
Cell Reports, Vol 15, Iss 6, Pp 1175-1189 (2016)
Like normal stem cells, tumor-initiating cells (T-ICs) are regulated extrinsically within the tumor microenvironment. Because HCC develops primarily in the context of cirrhosis, in which there is an enrichment of activated fibroblasts, we hypothesize
Externí odkaz:
https://doaj.org/article/3cdc6d5ccfb249248e8b45a87e42a838
Autor:
Bai-Liang He, Alvin C.H. Ma, May P.L. Cheung, Toni K. Man, Nelson K. L. Ng, Yuhan Guo, Dandan Wang, Xiangguo Shi, Anskar Y.H. Leung, Bowie Yik Ling Cheng
Publikováno v:
Stem Cell Reports
Summary ADP-ribosylation factor-like 4aa (Arl4aa) is a member of the ADP-ribosylation factor family. It is expressed in hematopoietic tissue during embryonic development, but its function was unknown. Zebrafish arl4aa is preferentially expressed in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::820c466feb1a828faaacceaba64edbdb
https://doi.org/10.1016/j.stemcr.2020.02.012
https://doi.org/10.1016/j.stemcr.2020.02.012
Autor:
Saborni Chakraborty, Joseph C. Gonzalez, Benjamin L. Sievers, Vamsee Mallajosyula, Srijoni Chakraborty, Megha Dubey, Usama Ashraf, Bowie Yik-Ling Cheng, Nimish Kathale, Kim Quyen Thi Tran, Courtney Scallan, Aanika Sinnott, Arianna Cassidy, Steven T. Chen, Terri Gelbart, Fei Gao, Yarden Golan, Xuhuai Ji, Seunghee Kim-Schulze, Mary Prahl, Stephanie L. Gaw, Sacha Gnjatic, Thomas U. Marron, Miriam Merad, Prabhu S. Arunachalam, Scott D. Boyd, Mark M. Davis, Marisa Holubar, Chaitan Khosla, Holden T. Maecker, Yvonne Maldonado, Elizabeth D. Mellins, Kari C. Nadeau, Bali Pulendran, Upinder Singh, Aruna Subramanian, Paul J. Utz, Robert Sherwood, Sheng Zhang, Prasanna Jagannathan, Gene S. Tan, Taia T. Wang
Publikováno v:
Science translational medicine, vol 14, iss 635
A damaging inflammatory response is implicated in the pathogenesis of severe coronavirus disease 2019 (COVID-19), but mechanisms contributing to this response are unclear. In two prospective cohorts, early non-neutralizing, afucosylated immunoglobuli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d71922fcd8a37cb20818c9a268fd390
https://escholarship.org/uc/item/9hs8r8gd
https://escholarship.org/uc/item/9hs8r8gd
Autor:
Dandan Wang, Lichuan Zheng, Bowie Yik Ling Cheng, Chun-Fung Sin, Runsheng Li, Sze Pui Tsui, Xinyu Yi, Alvin Chun Hang Ma, Bai Liang He, Anskar Yu Hung Leung, Xuan Sun
Publikováno v:
Oncogene. 42:1331-1331
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01a83892bd7e4e44988478a82c3b0163
https://doi.org/10.1038/s41388-023-02664-z
https://doi.org/10.1038/s41388-023-02664-z
Autor:
Saborni Chakraborty, Joseph C. Gonzalez, Benjamin L. Sievers, Vamsee Mallajosyula, Srijoni Chakraborty, Megha Dubey, Usama Ashraf, Bowie Yik-Ling Cheng, Nimish Kathale, Kim Quyen Thi Tran, Courtney Scallan, Aanika Sinnott, Arianna Cassidy, Steven T. Chen, Terri Gelbart, Fei Gao, Yarden Golan, Xuhuai Ji, Seunghee Kim-Schulze, Mary Prahl, Stephanie L. Gaw, Sacha Gnjatic, Thomas U. Marron, Miriam Merad, Prabhu S. Arunachalam, Scott D. Boyd, Mark M. Davis, Marisa Holubar, Chaitan Khosla, Holden T. Maecker, Yvonne Maldonado, Elizabeth D. Mellins, Kari C. Nadeau, Bali Pulendran, Upinder Singh, Aruna Subramanian, Paul J. Utz, Robert Sherwood, Sheng Zhang, Prasanna Jagannathan, Gene S. Tan, Taia T. Wang
Publikováno v:
bioRxiv
Serologic markers that predict severe COVID-19 disease trajectories could enable early medical interventions and reduce morbidity and mortality. We found that distinct features of IgG Fab and Fc domain structures were present within three days of a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b59bab957c4383db848c9114a2bf138d
https://doi.org/10.1101/2021.05.25.445649
https://doi.org/10.1101/2021.05.25.445649
Autor:
Chi Ho Lin, Regina Cheuk-Lam Lo, Carmen Oi Ning Leung, Nicole Pui Yu Ho, Eunice Y. Lau, Bowie Yik Ling Cheng, Terence K. Lee, Shilpa Gurung, Hoi-Wing Leung, Lily Kwan Wai Cheng, Stephanie Ma, Irene Oi-Lin Ng
Publikováno v:
Cancer Research. 78:2332-2342
Frequent relapse and drug resistance in patients with hepatocellular carcinoma (HCC) can be attributed to the existence of tumor-initiating cells (TIC) within the tumor bulk. Therefore, targeting liver TICs may improve the prognosis of these patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::550a422c0094ca4c50ff5007df3fbe9a
https://doi.org/10.1158/0008-5472.can-17-2445
https://doi.org/10.1158/0008-5472.can-17-2445
Autor:
Irene Oi-Lin Ng, Bowie Yik Ling Cheng, Eunice Yuen Ting Lau, Kin Wah Lee, Doris Hoi Wing Leung
Publikováno v:
Cancer Research. 78:1986-1986
Frequent relapse and drug resistance can be attributed to the existence of tumor-initiating cells (T-ICs) within the tumor bulk. From transcriptome sequencing of 16 pairs of clinical HCC samples, we found that Interleukin-1 receptor-associated kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::760629f86e0895dbffd02d1795b7f206
https://doi.org/10.1158/1538-7445.am2018-1986
https://doi.org/10.1158/1538-7445.am2018-1986
Publikováno v:
Journal of Liver: Disease & Transplantation.
Interleukin-1 receptor-associated kinase (IRAK) family consistsof four members: IRAK1, IRAK2, IRAK3/M and IRAK4. They are key downstream mediators of toll-like receptor (TLR) and interleukin-1 receptor (IL1R) pathways.In particular, TLR, a family of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de6acea0252d911098b39fce86660c37
https://doi.org/10.4172/2325-9612.1000e110
https://doi.org/10.4172/2325-9612.1000e110