Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors.

Autor: Saldivia M; York Biomedical Research Institute and Department of Biology, University of York, York, UK.; Novartis Institute for Tropical Diseases, Emeryville, CA, USA., Fang E; Novartis Institutes for Biomedical Research, Emeryville, CA, USA., Ma X; Novartis Institutes for Biomedical Research, Emeryville, CA, USA., Myburgh E; York Biomedical Research Institute, Hull York Medical School, University of York, York, UK., Carnielli JBT; York Biomedical Research Institute and Department of Biology, University of York, York, UK., Bower-Lepts C; York Biomedical Research Institute and Department of Biology, University of York, York, UK., Brown E; York Biomedical Research Institute and Department of Biology, University of York, York, UK., Ritchie R; Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK., Lakshminarayana SB; Novartis Institute for Tropical Diseases, Emeryville, CA, USA., Chen YL; Novartis Institute for Tropical Diseases, Emeryville, CA, USA., Patra D; Novartis Institute for Tropical Diseases, Emeryville, CA, USA., Ornelas E; Novartis Institutes for Biomedical Research, Emeryville, CA, USA., Koh HXY; Novartis Institute for Tropical Diseases, Emeryville, CA, USA., Williams SL; Novartis Institutes for Biomedical Research, Emeryville, CA, USA., Supek F; Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA., Paape D; Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK., McCulloch R; Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK., Kaiser M; Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland., Barrett MP; Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK., Jiricek J; Novartis Institute for Tropical Diseases, Emeryville, CA, USA., Diagana TT; Novartis Institute for Tropical Diseases, Emeryville, CA, USA., Mottram JC; York Biomedical Research Institute and Department of Biology, University of York, York, UK. jeremy.mottram@york.ac.uk., Rao SPS; Novartis Institute for Tropical Diseases, Emeryville, CA, USA. srinivasa.rao@novartis.com.

Publikováno v: Nature microbiology [Nat Microbiol] 2020 Oct; Vol. 5 (10), pp. 1207-1216. Date of Electronic Publication: 2020 Jul 13.

Isoliensinine from Cissampelos pariera rhizomes exhibits potential gametocytocidal and anti-malarial activities against Plasmodium falciparum clinical isolates.

Autor: Muema, Jackson M.^1,2 (AUTHOR) Jackson_mbithi@yahoo.com, Mutunga, James M.^2,3,4 (AUTHOR), Obonyo, Meshack A.⁵ (AUTHOR), Getahun, Merid N.⁶ (AUTHOR), Mwakubambanya, Ramadhan S.⁵ (AUTHOR), Akala, Hoseah M.² (AUTHOR), Cheruiyot, Agnes C.² (AUTHOR), Yeda, Redemptah A.² (AUTHOR), Juma, Dennis W.² (AUTHOR), Andagalu, Ben² (AUTHOR), Johnson, Jaree L.² (AUTHOR), Roth, Amanda L.² (AUTHOR), Bargul, Joel L.^1,6 (AUTHOR) jbargul@jkuat.ac.ke

Publikováno v: Malaria Journal. 5/20/2023, p1-15. 15p.

A profile of research on the parasitic trypanosomatids and the diseases they cause.

Autor: Horn, David¹ (AUTHOR) d.horn@dundee.ac.uk

Publikováno v: PLoS Neglected Tropical Diseases. 1/13/2022, Vol. 15 Issue 1, p1-23. 23p.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Tag Thy Neighbour: Nanometre-Scale Insights Into Kinetoplastid Parasites With Proximity Dependent Biotinylation.

Autor: Geoghegan, Vincent, Mottram, Jeremy C., Jones, Nathaniel G.

Publikováno v: Frontiers in Cellular & Infection Microbiology; 5/6/2022, Vol. 12, p1-14, 14p