Hydrophilic scaffolds of oxime as the potent catalytic inactivator of reactive organophosphate

Autor: Tang, Shengzhuang, Wong, Pamela T., Cannon, Jayme, Yang, Kelly, Bowden, Sierra, Bhattacharjee, Somnath, O'Konek, Jessica J., Choi, Seok Ki

Publikováno v: In Chemico-Biological Interactions 5 January 2019 297:67-79

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The epigenetic reader Brd4 is required for osteoblast differentiation.

Autor: Paradise, Christopher R., Galvan, M. Lizeth, Kubrova, Eva, Bowden, Sierra, Liu, Esther, Carstens, Mason F., Thaler, Roman, Stein, Gary S., Wijnen, Andre J., Dudakovic, Amel

Publikováno v: Journal of Cellular Physiology; Jun2020, Vol. 235 Issue 6, p5293-5304, 12p

Reactivity and mechanism of α-nucleophile scaffolds as catalytic organophosphate scavengers.

Autor: Wong, Pamela T., Bhattacharjee, Somnath, Cannon, Jayme, Tang, Shengzhuang, Yang, Kelly, Bowden, Sierra, Varnau, Victoria, O'Konek, Jessica J., Choi, Seok Ki

Publikováno v: Organic & Biomolecular Chemistry; 4/28/2019, Vol. 17 Issue 16, p3951-3963, 13p

Dual quorum-sensing control of purine biosynthesis drives pathogenic fitness of Enterococcus faecalis .

Autor: Zlitni S; Department of Genetics, Stanford University, Stanford, CA, USA.; Department of Medicine (Hematology, Blood and Marrow Transplantation), Stanford University, Stanford, CA, USA., Bowden S; Department of Genetics, Stanford University, Stanford, CA, USA., Sberro H; Department of Genetics, Stanford University, Stanford, CA, USA.; Department of Medicine (Hematology, Blood and Marrow Transplantation), Stanford University, Stanford, CA, USA., Torres MDT; Machine Biology Group, Departments of Psychiatry and Microbiology, Institute for Biomedical Informatics, Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania; Philadelphia, Pennsylvania 19104, USA.; Departments of Bioengineering and Chemical and Biomolecular Engineering, School of Engineering and Applied Science, University of Pennsylvania; Philadelphia, Pennsylvania 19104, USA.; Department of Chemistry, School of Arts and Sciences, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.; Penn Institute for Computational Science, University of Pennsylvania; Philadelphia, Pennsylvania 19104, USA., Vaughan JM; Clayton Foundation Laboratories for Peptide Biology, Salk Institute for Biological Studies, San Diego, CA, USA., Pinto AFM; Clayton Foundation Laboratories for Peptide Biology, Salk Institute for Biological Studies, San Diego, CA, USA., Pinto Y; Department of Genetics, Stanford University, Stanford, CA, USA.; Department of Medicine (Hematology, Blood and Marrow Transplantation), Stanford University, Stanford, CA, USA., Fernandez D; Program in Chemistry, Engineering, and Medicine for Human Health (ChEM-H), Stanford University, Stanford, CA 94305, USA.; Sarafan ChEM-H Macromolecular Structure Knowledge Center, Stanford University, Stanford, CA 94305, USA., Röst H; Department of Molecular Genetics, Donnelly Centre for Cellular and Biomolecular Research, The University of Toronto, Toronto, ON, Canada., Saghatelian A; Clayton Foundation Laboratories for Peptide Biology, Salk Institute for Biological Studies, San Diego, CA, USA., de la Fuente-Nunez C; Machine Biology Group, Departments of Psychiatry and Microbiology, Institute for Biomedical Informatics, Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania; Philadelphia, Pennsylvania 19104, USA.; Departments of Bioengineering and Chemical and Biomolecular Engineering, School of Engineering and Applied Science, University of Pennsylvania; Philadelphia, Pennsylvania 19104, USA.; Department of Chemistry, School of Arts and Sciences, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.; Penn Institute for Computational Science, University of Pennsylvania; Philadelphia, Pennsylvania 19104, USA., Bhatt AS; Department of Genetics, Stanford University, Stanford, CA, USA.; Department of Medicine (Hematology, Blood and Marrow Transplantation), Stanford University, Stanford, CA, USA.; Lead contact.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Aug 13. Date of Electronic Publication: 2024 Aug 13.