Zobrazeno 1 - 10
of 219
pro vyhledávání: '"Bow Ho"'
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Abstract The biofilm-forming-capability of Helicobacter pylori has been suggested to be among factors influencing treatment outcome. However, H. pylori exhibit strain-to-strain differences in biofilm-forming-capability. Metabolomics enables the infer
Externí odkaz:
https://doaj.org/article/8dc8334fe4c94339a672209200d392de
Autor:
Eric Hong Jian Wong, Chow Goon Ng, Eng Guan Chua, Alfred Chin Yen Tay, Fanny Peters, Barry J Marshall, Bow Ho, Khean Lee Goh, Jamuna Vadivelu, Mun Fai Loke
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166835 (2016)
Biofilm formation by Helicobacter pylori may be one of the factors influencing eradication outcome. However, genetic differences between good and poor biofilm forming strains have not been studied.Biofilm yield of 32 Helicobacter pylori strains (stan
Externí odkaz:
https://doaj.org/article/af87389ae2bd4b8993322ed2d0314d8f
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131460 (2015)
Helicobacter pylori causes cellular vacuolation in host cells, a cytotoxic event attributed to vacuolating cytotoxin (VacA) and the presence of permeant weak bases such as ammonia. We report here the role of γ-glutamyl transpeptidase (GGT), a consti
Externí odkaz:
https://doaj.org/article/f1584a291dc34ebab116a9acf0328b5f
Autor:
Victoria Serelli-Lee, Khoon Lin Ling, Cassandra Ho, Lai Han Yeong, Gek Keow Lim, Bow Ho, Soon Boon Justin Wong
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39199 (2012)
BACKGROUND: Ongoing Helicobacter pylori (HP) infection triggers a chronic active gastritis. Eradicating HP reduces gastric inflammation, but does not eliminate it. We sought to characterize this persistent gastritis, and demonstrate the persistence o
Externí odkaz:
https://doaj.org/article/e04d08fedbd74d30b690b83f048d4b6c
Autor:
Rajesh T Shenoy, Saravanan Thangamani, Adrian Velazquez-Campoy, Bow Ho, Jeak Ling Ding, J Sivaraman
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18838 (2011)
Serine proteases play a crucial role in host-pathogen interactions. In the innate immune system of invertebrates, multi-domain protease inhibitors are important for the regulation of host-pathogen interactions and antimicrobial activities. Serine pro
Externí odkaz:
https://doaj.org/article/cfb91e87767446a7a4b03f176c952e1d
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19647 (2011)
BACKGROUND: M-ficolin, a pathogen recognition molecule in the innate immune system, binds sugar residues including N-acetyl-D-glucosamine (GlcNAc), which is displayed on invading microbes and on apoptotic cells. The cis and trans Asp282-Cys283 peptid
Externí odkaz:
https://doaj.org/article/65569fab4ac14304a9d57c8275fa57b3
Autor:
Bing Liu, Jing Zhang, Pei Yi Tan, David Hsu, Anna M Blom, Benjamin Leong, Sunil Sethi, Bow Ho, Jeak Ling Ding, P S Thiagarajan
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 1, p e1001059 (2011)
The complement system is key to innate immunity and its activation is necessary for the clearance of bacteria and apoptotic cells. However, insufficient or excessive complement activation will lead to immune-related diseases. It is so far unknown how
Externí odkaz:
https://doaj.org/article/9fae6add3ab946339cc6854f91aa963c
Autor:
Sook Yin Lui BSc (Hons), PhD, Sai Wei Chuah MBBS, MRCP(UK), Hui Lin Goh BSc (Hons), Kar Yee Lee BSc (Hons), Victoria Serelli Lee BSc (Hons), Bow Ho BSc (Hons), PhD, Khoon Lin Ling MBBS, PhD
Publikováno v:
Proceedings of Singapore Healthcare, Vol 19 (2010)
Aim: Helicobacter pylori causes peptic ulcer disease and gastric cancer. Western studies suggest that polymorphisms in the virulence factors cagA and vacA may determine the ability of bacteria to cause gastroduodenal diseases. Differences in the cagA
Externí odkaz:
https://doaj.org/article/f3da43cff63d4631b09e09d0eb4f573a
Autor:
Jing Zhang, Jingyun Koh, Jinhua Lu, Steffen Thiel, Benjamin S H Leong, Sunil Sethi, Cynthia Y X He, Bow Ho, Jeak L Ding
Publikováno v:
PLoS Pathogens, Vol 5, Iss 1, p e1000282 (2009)
By eliciting inflammatory responses, the human immunosurveillance system notably combats invading pathogens, during which acute phase proteins (CRP and cytokines) are elevated markedly. However, the Pseudomonas aeruginosa is a persistent opportunisti
Externí odkaz:
https://doaj.org/article/30320c553f0f4a61834d5254efc929e6
Autor:
Diana Hooi Ping Low, Zhiwei Ang, Quan Yuan, Vladimir Frecer, Bow Ho, Jianzhu Chen, Jeak Ling Ding
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6260 (2009)
BACKGROUND: Although the human genome database has been completed a decade ago, approximately 50% of the proteome remains hypothetical as their functions are unknown. The elucidation of the functions of these hypothetical proteins can lead to additio
Externí odkaz:
https://doaj.org/article/6350975e4d2c444788f2acdd5a42aab6