Zobrazeno 1 - 10
of 1 068
pro vyhledávání: '"Bovine pancreatic ribonuclease"'
Autor:
Mostafa Akbarzadeh Khiavi, Azam Safary, Jaleh Barar, Hamed Farzi-Khajeh, Abolfazl Barzegari, Rahimeh Mousavi, Mohammad Hossein Somi, Yadollah Omidi
Publikováno v:
BioImpacts, Vol 10, Iss 1, Pp 27-36 (2020)
Introduction: Currently, drug-induced reactive oxygen species (ROS) mediating apoptosis pathway have extensively been investigated in designing effective strategies for colorectal cancer (CRC) chemotherapy. Bovine pancreatic ribonuclease A (RNase A)
Externí odkaz:
https://doaj.org/article/1d773cc4fb35482baa55337886a2c04e
Publikováno v:
ACS Omega, Vol 6, Iss 1, Pp 533-543 (2021)
ACS Omega
ACS Omega
Using bovine pancreatic ribonuclease A (RNase A) and cholesterol, we synthesized cholesteryl-conjugated ribonuclease A (CHRNase A) to evaluate the influence of a conjugated hydrophobic moiety on protein function. Nuclear magnetic resonance and matrix
Publikováno v:
Inorganic Chemistry Frontiers. 8:1795-1803
Herein, we present a detailed metalation process of the bovine pancreatic ribonuclease (RNase A) by a novel multitarget anti-cancer agent arsenoplatin-1, AP1, ([Pt(μ-NHC(CH3)O)2ClAs(OH)2]), on the basis of quantum chemical investigation, employing t
Autor:
Giarita Ferraro, Francesca Sacco, Antonello Merlino, Lara Massai, Giorgio Facchetti, Matteo Tarchi, Isabella Rimoldi, Luigi Messori
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 10551, p 10551 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 19
International Journal of Molecular Sciences
Volume 22
Issue 19
Three novel platinum(II) complexes bearing N-heterocyclic ligands, i.e., Pt2c, Pt-IV and Pt-VIII, were previously prepared and characterized. They manifested promising in vitro anticancer properties associated with non-conventional modes of action. T
Autor:
Mostafa Akbarzadeh Khiavi, Hamed Farzi-Khajeh, Jaleh Barar, Abolfazl Barzegari, Azam Safary, Yadollah Omidi, Mohammad Hossein Somi, Rahimeh Mousavi
Publikováno v:
BioImpacts : BI
BioImpacts, Vol 10, Iss 1, Pp 27-36 (2020)
BioImpacts, Vol 10, Iss 1, Pp 27-36 (2020)
Introduction: Currently, drug-induced reactive oxygen species (ROS) mediating apoptosis pathway have extensively been investigated in designing effective strategies for colorectal cancer (CRC) chemotherapy. Bovine pancreatic ribonuclease A (RNase A)
Autor:
Michelle Dechene, Kendra Marcus, Bradley M. Kearney, Michael Schwabe, Daniel M. Roberts, Paul Swartz, Carla Mattos
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 88:152-165
Water and ligand binding play critical roles in the structure and function of proteins, yet their binding sites and significance are difficult to predict a priori. Multiple solvent crystal structures (MSCS) is a method where several X-ray crystal str
Autor:
Shapiro, Robert, Vallee, Bert L.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1987 Apr . 84(8), 2238-2241.
Externí odkaz:
https://www.jstor.org/stable/29686
Akademický článek
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Autor:
Eugenio Garribba, Valeria Ugone, Nicola Demitri, Daniele Sanna, Luigi Vitale, Giuseppe Sciortino, Giarita Ferraro, Antonello Merlino
Publikováno v:
Inorganic Chemistry
Inorganic chemistry 60 (2021): 19098–19109. doi:10.1021/acs.inorgchem.1c02912
info:cnr-pdr/source/autori:Ferraro G.; Demitri N.; Vitale L.; Sciortino G.; Sanna D.; Ugone V.; Garribba E.; Merlino A./titolo:Spectroscopic%2FComputational Characterization and the X-ray Structure of the Adduct of the VIVO-Picolinato Complex with RNase A/doi:10.1021%2Facs.inorgchem.1c02912/rivista:Inorganic chemistry/anno:2021/pagina_da:19098/pagina_a:19109/intervallo_pagine:19098–19109/volume:60
Inorganic chemistry 60 (2021): 19098–19109. doi:10.1021/acs.inorgchem.1c02912
info:cnr-pdr/source/autori:Ferraro G.; Demitri N.; Vitale L.; Sciortino G.; Sanna D.; Ugone V.; Garribba E.; Merlino A./titolo:Spectroscopic%2FComputational Characterization and the X-ray Structure of the Adduct of the VIVO-Picolinato Complex with RNase A/doi:10.1021%2Facs.inorgchem.1c02912/rivista:Inorganic chemistry/anno:2021/pagina_da:19098/pagina_a:19109/intervallo_pagine:19098–19109/volume:60
The structure, stability, and enzymatic activity of the adduct formed upon the reaction of the V–picolinato (pic) complex [VIVO(pic)2(H2O)], with an octahedral geometry and the water ligand in cis to the V=O group, with the bovine pancreatic ribonu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25656f0858bd048a8e2ccd1c061cbed4
https://hdl.handle.net/11588/874639
https://hdl.handle.net/11588/874639
Publikováno v:
Bioconjug Chem
Since its conception, the ribonuclease S complex (RNase S) has led to historic discoveries in protein chemistry, enzymology, and related fields. Derived by the proteolytic cleavage of a single peptide bond in bovine pancreatic ribonuclease (RNase A),